ChemicalBook > CAS DataBase List > Paquinimod

Paquinimod

Product Name
Paquinimod
CAS No.
248282-01-1
Chemical Name
Paquinimod
Synonyms
ABR25757;ABR 25757;ABR-25757;ABR?215757;Paquinimod;ABR?215757; ABR 215757; ABR215757; PAQUINIMOD.;ABR-25757,Inhibitor,ABR25757,inhibit,Paquinimod;ABR 25757;ABR-25757;ABR25757;PAQUINIMOD;248282-01-1;N,5-diethyl-4-hydroxy-1-methyl-2-oxo-N-phenylquinoline-3-carboxamide;N,5-diethyl-4-hydroxy-1-methyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide
CBNumber
CB92498835
Molecular Formula
C21H22N2O3
Formula Weight
350.41
MOL File
248282-01-1.mol
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Paquinimod Property

Boiling point:
487.3±45.0 °C(Predicted)
Density 
1.267±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO:15.0(Max Conc. mg/mL);42.8(Max Conc. mM)
form 
A solid
pka
4.50±1.00(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
28443
Product name
Paquinimod
Packaging
1mg
Price
$55
Updated
2024/03/01
Cayman Chemical
Product number
28443
Product name
Paquinimod
Packaging
25mg
Price
$914
Updated
2024/03/01
Cayman Chemical
Product number
28443
Product name
Paquinimod
Packaging
5mg
Price
$224
Updated
2024/03/01
Cayman Chemical
Product number
28443
Product name
Paquinimod
Packaging
10mg
Price
$420
Updated
2024/03/01
AK Scientific
Product number
1997DM
Product name
Paquinimod
Packaging
5mg
Price
$146
Updated
2021/12/16
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Paquinimod Chemical Properties,Usage,Production

Uses

Paquinimod is a S100A9 inhibitor preventing S100A9 binding to TLR-4. Paquinimod reduces pathology in experimental collagenase-induced osteoarthritis. Paquinimod treatment of collagenase-induced OA (CIOA) resulted in significantly reduced synovial thickening (57%), osteophyte size at the medial femur (66%) and cruciate ligaments (67%) and cartilage damage at the medial tibia (47%) and femur (75%; n=7, untreated n=6). Paquinimod reduces leukocyte recruitment during sterile inflammation. Paquinimod also reduced priming of proinflammatory effector CD4(+) T cells.

Paquinimod Preparation Products And Raw materials

Raw materials

Preparation Products

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Paquinimod Suppliers

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248282-01-1, PaquinimodRelated Search:

N,N'-Ethylenebis(stearamide) Deionized water (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride

  • ABR?215757
  • N,5-diethyl-4-hydroxy-1-methyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide
  • ABR 25757
  • ABR 25757;ABR-25757;ABR25757;PAQUINIMOD;248282-01-1
  • ABR25757
  • ABR-25757
  • ABR?215757; ABR 215757; ABR215757; PAQUINIMOD.
  • Paquinimod
  • N,5-diethyl-4-hydroxy-1-methyl-2-oxo-N-phenylquinoline-3-carboxamide
  • 3-Quinolinecarboxamide, N,5-diethyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-N-phenyl-
  • ABR-25757,Inhibitor,ABR25757,inhibit,Paquinimod
  • 248282-01-1