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AM1172

Product Name
AM1172
CAS No.
251908-92-6
Chemical Name
AM1172
Synonyms
AM1172;N-5Z,8Z,11Z,14Z-EICOSATETRAENYL-4-HYDROXY-BENZAMIDE;4-hydroxy-N-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenyl]benzamide;N-(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraen-1-yl-4-hydroxybenzamide;Benzamide, N-(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraen-1-yl-4-hydroxy-
CBNumber
CB9251038
Molecular Formula
C27H39NO2
Formula Weight
409.6
MOL File
251908-92-6.mol
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AM1172 Property

Boiling point:
590.8±50.0 °C(Predicted)
Density 
0.983±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in ethanol
form 
solution in ethanol
pka
8.53±0.26(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10005223
Product name
AM1172
Purity
≥98%
Packaging
5mg
Price
$87
Updated
2024/03/01
Cayman Chemical
Product number
10005223
Product name
AM1172
Purity
≥98%
Packaging
10mg
Price
$163
Updated
2024/03/01
Cayman Chemical
Product number
10005223
Product name
AM1172
Purity
≥98%
Packaging
50mg
Price
$680
Updated
2024/03/01
Cayman Chemical
Product number
10005223
Product name
AM1172
Purity
≥98%
Packaging
100mg
Price
$1189
Updated
2024/03/01
Tocris
Product number
3381
Product name
AM1172
Purity
≥98%(HPLC)
Packaging
10
Price
$193
Updated
2021/12/16
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AM1172 Chemical Properties,Usage,Production

Uses

AM 1172 is a potent and selective inhibitor of anandamide uptake and FAAH.

Biological Activity

Metabolically stable anandamide uptake inhibitor (IC 50 = 2.1 - 2.5 μ M) and fatty acid amide hydrolase (FAAH) inhibitor (K i = 3.18 μ M). Inhibits N -arachidonylethanolamine (AEA) accumulation (IC 50 = 24 μ M) and hydrolysis (K i = 3 μ M), and inhibits N -palmitoylethanolamine (PEA) hydrolysis (IC 50 = 36 μ M) in cerebellar granule neurons. Also acts as a non-selective cannabinoid receptor partial agonist (EC 50 values are 189 and 271 nM at CB 2 and CB 1 receptors respectively).

References

1. fegley d, kathuria s, mercier r, et al. anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor am1172. proceedings of the national academy of sciences of the united states of america. 2004;101(23):8756-8761.

AM1172 Preparation Products And Raw materials

Raw materials

Preparation Products

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AM1172 Suppliers

CHINA 22 Switzerland 1 United Kingdom 1 United States 6 Global 30
3B Pharmachem (Wuhan) International Co.,Ltd.
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marketing@energy-chemical.com
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251908-92-6, AM1172Related Search:

AM1172

  • N-5Z,8Z,11Z,14Z-EICOSATETRAENYL-4-HYDROXY-BENZAMIDE
  • 4-hydroxy-N-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenyl]benzamide
  • AM1172
  • N-(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraen-1-yl-4-hydroxybenzamide
  • Benzamide, N-(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraen-1-yl-4-hydroxy-
  • 251908-92-6