ChemicalBook > CAS DataBase List > MIRA-1

MIRA-1

Product Name
MIRA-1
CAS No.
72835-26-8
Chemical Name
MIRA-1
Synonyms
MIRA-1;NSC 19630;p53 Activator VIII;WRN Helicase Inhibitor;1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2;(2,5-dioxopyrrol-1-yl)methyl propanoate;5-dihydro-1H-pyrrol-1-yl)methyl propionate;Ethyl 2,5-Dioxo-2,5-dihydropyrrole-1-acetate;1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 1-[(1-oxopropoxy)methyl]-
CBNumber
CB92514665
Molecular Formula
C8H9NO4
Formula Weight
183.16
MOL File
72835-26-8.mol
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MIRA-1 Property

Melting point:
44 °C
Boiling point:
298.2±23.0 °C(Predicted)
Density 
1.307±0.06 g/cm3(Predicted)
storage temp. 
Store at +4°C
solubility 
Soluble to 100 mM in DMSO and to 100 mM in ethanol
form 
Powder
pka
-2.79±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
681647
Product name
WRN Helicase Inhibitor, NSC 19630 - CAS 72835-26-8 - Calbiochem
Packaging
5MG
Price
$144
Updated
2024/03/01
Cayman Chemical
Product number
14858
Product name
MIRA-1
Purity
≥98%
Packaging
10mg
Price
$106
Updated
2024/03/01
Cayman Chemical
Product number
14858
Product name
MIRA-1
Purity
≥98%
Packaging
50mg
Price
$440
Updated
2024/03/01
Tocris
Product number
3362
Product name
MIRA-1
Packaging
10
Price
$119
Updated
2021/12/16
TRC
Product number
N900430
Product name
MIRA-1
Packaging
10mg
Price
$60
Updated
2021/12/16
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MIRA-1 Chemical Properties,Usage,Production

Uses

The tumor suppressor gene, p53, is often mutated in most human cancers. MIRA-1 is a maleimide-derived molecule that can reactivate the mutant p53 leading to apoptosis in human tumor cells. In addition, the MIRA scaffold is an attractive lead for developing anticancer drugs that target mutant p53.

storage

Store at +4°C

MIRA-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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MIRA-1 Suppliers

China 38 United Kingdom 1 United States 7 Global 46
3B Pharmachem (Wuhan) International Co.,Ltd.
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Shanghai Raise Chemical Technology Co.,Ltd
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Bide Pharmatech Ltd.
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400-1647117 15221909166
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+86-21-61629029
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product02@bidepharm.com
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Shanghai SuperLan Chemcial Technique Centre
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021-2022843681 15618226720
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+86-21-51601218
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Henan Weituxi Chemical Technology Co., Ltd.
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0371-63284658 18135795563
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18818260767
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order@med-bio.cn
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PharmaBlock Sciences (Nanjing), Inc.
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72835-26-8, MIRA-1Related Search:


  • MIRA-1
  • 1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2,5-dione
  • NSC 19630
  • 1H-Pyrrole-2,5-dione, 1-[(1-oxopropoxy)methyl]-
  • Ethyl 2,5-Dioxo-2,5-dihydropyrrole-1-acetate
  • 1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2
  • 5-dihydro-1H-pyrrol-1-yl)methyl propionate
  • p53 Activator VIII
  • WRN Helicase Inhibitor
  • inhibit,MDM-2/p53,MIRA1,Apoptosis,NSC-19630,Inhibitor,H1299,MIRA-1,SKOV,NSC19630,Anticancer,MIRA 1,Saos-2
  • (2,5-dioxopyrrol-1-yl)methyl propanoate
  • 72835-26-8
  • Apoptosis Inducers