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MIRA-1

Product Name
MIRA-1
CAS No.
72835-26-8
Chemical Name
MIRA-1
Synonyms
MIRA-1;NSC 19630;MIRA-1(NSC 19630);p53 Activator VIII;WRN Helicase Inhibitor;1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2;(2,5-dioxopyrrol-1-yl)methyl propanoate;5-dihydro-1H-pyrrol-1-yl)methyl propionate;Ethyl 2,5-Dioxo-2,5-dihydropyrrole-1-acetate;1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2,5-dione
CBNumber
CB92514665
Molecular Formula
C8H9NO4
Formula Weight
183.16
MOL File
72835-26-8.mol
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MIRA-1 Property

Melting point:
44 °C
Boiling point:
298.2±23.0 °C(Predicted)
Density 
1.307±0.06 g/cm3(Predicted)
storage temp. 
Store at +4°C
solubility 
Soluble to 100 mM in DMSO and to 100 mM in ethanol
form 
Powder
pka
-2.79±0.20(Predicted)
color 
White to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
681647
Product name
WRN Helicase Inhibitor, NSC 19630 - CAS 72835-26-8 - Calbiochem
Packaging
5MG
Price
$144
Updated
2024/03/01
Cayman Chemical
Product number
14858
Product name
MIRA-1
Purity
≥98%
Packaging
10mg
Price
$106
Updated
2024/03/01
Cayman Chemical
Product number
14858
Product name
MIRA-1
Purity
≥98%
Packaging
50mg
Price
$440
Updated
2024/03/01
Tocris
Product number
3362
Product name
MIRA-1
Packaging
10
Price
$119
Updated
2021/12/16
TRC
Product number
N900430
Product name
MIRA-1
Packaging
10mg
Price
$60
Updated
2021/12/16
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MIRA-1 Chemical Properties,Usage,Production

Uses

The tumor suppressor gene, p53, is often mutated in most human cancers. MIRA-1 is a maleimide-derived molecule that can reactivate the mutant p53 leading to apoptosis in human tumor cells. In addition, the MIRA scaffold is an attractive lead for developing anticancer drugs that target mutant p53.

storage

Store at +4°C

MIRA-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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MIRA-1 Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
VDM Biochemicals
Tel
0330-2528181
Fax
0330-2528171
Email
sales@vdmbio.com
Country
United States
ProdList
510
Advantage
64
Shanghai Raise Chemical Technology Co.,Ltd
Tel
15026594951
Fax
0556-5030632
Email
rs@raise-chem.com
Country
China
ProdList
3576
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
SHANGHAI FDC-CHEMICAL CO.,LTD
Tel
021-61469567 13482353728
Fax
021-61161605
Email
sales@fdc-chemical.com
Country
China
ProdList
16474
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
Henan Weituxi Chemical Technology Co., Ltd.
Tel
0371-63284658 18135795563
Fax
QQ:2885349392
Email
2885349392@qq.com
Country
China
ProdList
10058
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58

72835-26-8, MIRA-1Related Search:


  • MIRA-1
  • 1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2,5-dione
  • NSC 19630
  • 1H-Pyrrole-2,5-dione, 1-[(1-oxopropoxy)methyl]-
  • Ethyl 2,5-Dioxo-2,5-dihydropyrrole-1-acetate
  • 1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2
  • 5-dihydro-1H-pyrrol-1-yl)methyl propionate
  • p53 Activator VIII
  • WRN Helicase Inhibitor
  • inhibit,MDM-2/p53,MIRA1,Apoptosis,NSC-19630,Inhibitor,H1299,MIRA-1,SKOV,NSC19630,Anticancer,MIRA 1,Saos-2
  • (2,5-dioxopyrrol-1-yl)methyl propanoate
  • MIRA-1(NSC 19630)
  • 72835-26-8
  • Apoptosis Inducers