α-Conotoxin MII
- Product Name
- α-Conotoxin MII
- CAS No.
- 175735-93-0
- Chemical Name
- α-Conotoxin MII
- Synonyms
- α-Conotoxin MII;α-Conotoxin MII;L-Cysteinamide, glycyl-L-cysteinyl-L-cysteinyl-L-seryl-L-asparaginyl-L-prolyl-L-valyl-L-cysteinyl-L-histidyl-L-leucyl-L-α-glutamyl-L-histidyl-L-seryl-L-asparaginyl-L-leucyl-, cyclic (2→8),(3→16)-bis(disulfide)
- CBNumber
- CB92518764
- Molecular Formula
- C67H103N23O22S4
- Formula Weight
- 1710.94
- MOL File
- 175735-93-0.mol
α-Conotoxin MII Property
- Boiling point:
- 2239.4±65.0 °C(Predicted)
- Density
- 1.51±0.1 g/cm3(Predicted)
- pka
- 4.46±0.10(Predicted)
- form
- Powder
- color
- White to off-white
- Water Solubility
- Soluble to 1 mg/ml in water
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H300Fatal if swallowed
H310Fatal in contact with skin
H330Fatal if inhaled
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P262Do not get in eyes, on skin, or on clothing.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284Wear respiratory protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P350IF ON SKIN: Gently wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P310Immediately call a POISON CENTER or doctor/physician.
P320Specific treatment is urgent (see … on this label).
P321Specific treatment (see … on this label).
P322Specific measures (see …on this label).
P330Rinse mouth.
P361Remove/Take off immediately all contaminated clothing.
P363Wash contaminated clothing before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
α-Conotoxin MII Chemical Properties,Usage,Production
Biological Activity
α-Conotoxin MII (α-CTxMII) can be isolated from the sea snail Conus magus and potently inhibits the α3β2 subunit of the nAChR receptor with an IC50 value of 0.5 nM. α-Conotoxin MII (α-CTxMII) potently inhibits β3-containing neuronicotine receptors.
in vitro
α-Conotoxin MII (0.5-3.5 nM) blocks ACh responses in oocytes expressing α3β2 nicotinic acetylcholine receptors.
target
IC50: 0.5 nM (α3β2).
storage
Store at -20°C
α-Conotoxin MII Preparation Products And Raw materials
Raw materials
Preparation Products
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