ChemicalBook > CAS DataBase List > Brevilin A

Brevilin A

Product Name
Brevilin A
CAS No.
16503-32-5
Chemical Name
Brevilin A
Synonyms
6-OAP;Brevilin A;Brevelin A;brevillin A;6-O-Angeloylplenolin;(3S,3aR,4S,4aR,7aR,8R,9aR)-3,4a,8-Trimethyl-2,5-dioxo-2,3,3a,4,4a,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl (Z)-2-methylbut-2-enoate;(3S,3aR,4S,4aR,7aR,8R,9aR)-3,4a,8-Trimethyl-2,5-dioxo-2,3,3a,4,4a ,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl (2Z)-2-methyl-2-bu tenoate;2-Butenoic acid,2-methyl-,(3S,3aR,4S,4aR,7aR,8R,9aR)-2,3,3a,4,4a,5,7a,8,9,9a-decahydro-3,4a,8-trimethyl-2,5-dioxoazuleno[6,5-b]furan-4-ylester, (2Z)-
CBNumber
CB92519594
Molecular Formula
C20H26O5
Formula Weight
346.42
MOL File
16503-32-5.mol
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Brevilin A Property

Boiling point:
494.0±45.0 °C(Predicted)
Density 
1.17±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO:100.0(Max Conc. mg/mL);288.67(Max Conc. mM)
form 
A solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL84204
Product name
Brevilin A
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$629
Updated
2024/03/01
ChemScene
Product number
CS-0023593
Product name
Brevilin A
Purity
99.77%
Packaging
5mg
Price
$250
Updated
2021/12/16
ChemScene
Product number
CS-0023593
Product name
Brevilin A
Purity
99.77%
Packaging
10mg
Price
$430
Updated
2021/12/16
Crysdot
Product number
CD32002260
Product name
Brevilin A
Purity
95+%
Packaging
5mg
Price
$450
Updated
2021/12/16
AvaChem
Product number
4099
Product name
Brevilin A
Packaging
10mg
Price
$490
Updated
2021/12/16
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Brevilin A Chemical Properties,Usage,Production

Uses

Brevilin A can be used using a selective extraction method to obtain natural substances, and can also be applied to prepare derivatives to use for anti-cancer activity.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Enzyme inhibitor

This naturally occurring sesquiterpenoid (FW = 346.40 g/mol; CAS 16503- 32-5) from the volatile oils of the plant Centipeda minima inhibits (IC50 = 10 μg/mL) STAT3 phosphorylation in the Jak/STAT signal transduction pathway of A549R cells. Brevilin A showed high specificity on Janus Kinase activity and following STAT3 signaling without directly affecting some other signals, including p65, AKT and GSK-3β phosphorylation, as well as Src kinase activity. Brevilin A is also an antibiotic with activity against Giardia (IC50 = 16 μM) and Entamoeba histolitica (IC50 = 4–9 μM).

Brevilin A Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Brevilin A manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Product
Brevilin A 16503-32-5
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000ton
Release date
2023-08-21
Career Henan Chemical Co
Product
Brevilin A 16503-32-5
Price
US $9.80/KG
Min. Order
1g
Purity
>98%
Supply Ability
20 tons
Release date
2020-02-10

16503-32-5, Brevilin ARelated Search:


  • Brevilin A
  • 6-O-Angeloylplenolin
  • 2-Butenoic acid,2-methyl-,(3S,3aR,4S,4aR,7aR,8R,9aR)-2,3,3a,4,4a,5,7a,8,9,9a-decahydro-3,4a,8-trimethyl-2,5-dioxoazuleno[6,5-b]furan-4-ylester, (2Z)-
  • (3S,3aR,4S,4aR,7aR,8R,9aR)-3,4a,8-Trimethyl-2,5-dioxo-2,3,3a,4,4a ,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl (2Z)-2-methyl-2-bu tenoate
  • brevillin A
  • Brevelin A
  • 6-OAP
  • (3S,3aR,4S,4aR,7aR,8R,9aR)-3,4a,8-Trimethyl-2,5-dioxo-2,3,3a,4,4a,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl (Z)-2-methylbut-2-enoate
  • 16503-32-5