7-Quinazolinecarboxylic acid, 2-chloro-, methyl ester
- Product Name
- 7-Quinazolinecarboxylic acid, 2-chloro-, methyl ester
- CAS No.
- 953039-79-7
- Chemical Name
- 7-Quinazolinecarboxylic acid, 2-chloro-, methyl ester
- Synonyms
- methyl 2-chloroquinazolin...;Methyl 2-chloro-7-quinazolinecarboxylate;Methyl 2-chloroquinazoline-7-carboxylate;Methyl 2-chloro-quinazolin-7-carboxylate;2-Chloro-7-quinazolinecarboxylic acid methyl ester;7-Quinazolinecarboxylic acid, 2-chloro-, Methyl ester
- CBNumber
- CB92525175
- Molecular Formula
- C10H7ClN2O2
- Formula Weight
- 222.63
- MOL File
- 953039-79-7.mol
7-Quinazolinecarboxylic acid, 2-chloro-, methyl ester Property
- Boiling point:
- 328.6±24.0 °C(Predicted)
- Density
- 1.392±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. -20°C
- pka
- -0.73±0.30(Predicted)
- Appearance
- Light yellow to light green Solid
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B499460
- Product name
- methyl2-chloroquinazoline-7-carboxylate
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CS-0046212
- Product name
- Methyl2-chloroquinazoline-7-carboxylate
- Purity
- >97.0%
- Packaging
- 100mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- CS-0046212
- Product name
- Methyl2-chloroquinazoline-7-carboxylate
- Purity
- >97.0%
- Packaging
- 250mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- CS-0046212
- Product name
- Methyl2-chloroquinazoline-7-carboxylate
- Purity
- >97.0%
- Packaging
- 1g
- Price
- $395
- Updated
- 2021/12/16
- Product number
- 4H23-5-24
- Product name
- Methyl 2-chloroquinazoline-7-carboxylate
- Packaging
- 1g
- Price
- $500
- Updated
- 2021/12/16
7-Quinazolinecarboxylic acid, 2-chloro-, methyl ester Chemical Properties,Usage,Production
Synthesis
953039-78-6
953039-79-7
Step 3. Preparation of methyl 2-chloroquinazoline-7-carboxylate To methyl 2-oxo-1,2-dihydroquinazoline-7-carboxylate (1.0 eq.) was added phosphorous trichloride (POCl3, 3.0 eq.), the reaction mixture was heated to 100 °C and the reaction was stirred at this temperature for 20 minutes. Upon completion of the reaction, the mixture was cooled to room temperature and the reaction was quenched by slowly pouring into ice water. The precipitated solid product was collected by filtration and washed with cold water. The resulting solid was dried overnight under high vacuum to afford methyl 2-chloroquinazoline-7-carboxylate in 60% yield. The product was confirmed by electrospray mass spectrometry (ES/MS), m/z 223 (MH+).
References
[1] Patent: WO2007/117607, 2007, A2. Location in patent: Page/Page column 341
7-Quinazolinecarboxylic acid, 2-chloro-, methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 7-Quinazolinecarboxylic acid, 2-chloro-, methyl ester manufacturers
- Product
- Methyl 2-chloroquinazolin... 953039-79-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-13
- Product
- Methyl 2-chloroquinazolin 953039-79-7
- Price
- US $5.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2020-01-12