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Mesaconine

Product Name
Mesaconine
CAS No.
6792-09-2
Chemical Name
Mesaconine
Synonyms
Mesaconine;product/155130;Inhibitor,inhibit,Mesaconine;(1alpha,3alpha,6alpha,14alpha,15alpha,16beta)-1,6,16-Trimethoxy-4-(methoxymethyl)-20-methyl-aconitane;Aconitane-3,8,13,14,15-pentol, 1,6,16-trimethoxy-4-(methoxymethyl)-20-methyl-, (1α,3α,6α,14α,15α,16β)-;(1alpha,3alpha,6alpha,14alpha,15alpha,16beta)-1,6,16-Trimethoxy-4-(methoxymethyl)-20-methyl-aconitane-3,8,13,14,15-pentol
CBNumber
CB92535794
Molecular Formula
C24H39NO9
Formula Weight
485.57
MOL File
6792-09-2.mol
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Mesaconine Property

Boiling point:
617.1±55.0 °C(Predicted)
Density 
1.44±0.1 g/cm3(Predicted)
solubility 
Aqueous Acid (Slightly), Chloroform (Slightly), Methanol (Slightly)
pka
12.22±0.70(Predicted)
form 
Solid
color 
White
Stability:
Moisture Sensitive
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0018233
Product name
Mesaconine
Packaging
1mg
Price
$286
Updated
2021/12/16
ApexBio Technology
Product number
N2248
Product name
mesaconine
Packaging
20mg
Price
$400
Updated
2021/12/16
ChemScene
Product number
CS-0018233
Product name
Mesaconine
Packaging
5mg
Price
$857
Updated
2021/12/16
Arctom
Product number
SY232661
Product name
Mesaconine
Purity
≥98%
Packaging
10mg
Price
$927.27
Updated
2021/12/16
AvaChem
Product number
3556
Product name
Mesaconine
Packaging
10mg
Price
$690
Updated
2021/12/16
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Mesaconine Chemical Properties,Usage,Production

Uses

New use of neoaconitrile in the preparation of medicaments for preventing and/or treating myocardial fibrosis and chronic heart failure caused by myocardial fibrosis

Biological Activity

Mesaconinean, the active ingredient extracted from Aconitum carmichaelii Debx., has cardiovascular effects.

Pharmacology

1) Inhibit or reverse myocardial tissue fibrosis; 2) Improve abnormal cardiac remodeling; 3) Improve cardiac dysfunction; 4) Improve the survival rate of mice with chronic heart failure caused by myocardial fibrosis; 5) Fight against myocardial tissue inflammation; 6 ) Inhibition of cardiomyocyte apoptosis; 7) Myocardial enzyme activity in dead mice, and its mechanism of action is related to inhibiting myocardial tissue inflammation and fibrosis caused by adriamycin and resisting cardiomyocyte apoptosis.

Mesaconine Preparation Products And Raw materials

Raw materials

Preparation Products

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6792-09-2, MesaconineRelated Search:


  • Mesaconine
  • (1alpha,3alpha,6alpha,14alpha,15alpha,16beta)-1,6,16-Trimethoxy-4-(methoxymethyl)-20-methyl-aconitane-3,8,13,14,15-pentol
  • product/155130
  • Aconitane-3,8,13,14,15-pentol, 1,6,16-trimethoxy-4-(methoxymethyl)-20-methyl-, (1α,3α,6α,14α,15α,16β)-
  • (1alpha,3alpha,6alpha,14alpha,15alpha,16beta)-1,6,16-Trimethoxy-4-(methoxymethyl)-20-methyl-aconitane
  • Inhibitor,inhibit,Mesaconine
  • 6792-09-2
  • 1787-01-3
  • C24H39NO9
  • Alkaloids
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract