ChemicalBook > CAS DataBase List > 4,13-Diaza-18-crown 6-ether

4,13-Diaza-18-crown 6-ether

Product Name
4,13-Diaza-18-crown 6-ether
CAS No.
23978-55-4
Chemical Name
4,13-Diaza-18-crown 6-ether
Synonyms
DIAZA-18-CROWN-6;cryptand22;cryptand2.2;KRYPTOFIX 22;CAS_23978-55-4;KRYPTOFIX(R) 22;KRYPTOFIX 22 99+%;Diaza-18-crown-6,98%;KRYPTOFIX 22 POLYMER;7,16-DIAZA-18-CROWN-6
CBNumber
CB9259458
Molecular Formula
C12H26N2O4
Formula Weight
262.35
MOL File
23978-55-4.mol
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4,13-Diaza-18-crown 6-ether Property

Melting point:
111-114 °C(lit.)
Boiling point:
405.6°C (rough estimate)
Density 
1.0807 (rough estimate)
refractive index 
1.4560 (estimate)
storage temp. 
Store below +30°C.
form 
Shiny Crystalline Powder
pka
9.00±0.20(Predicted)
color 
Off-white
Water Solubility 
Soluble in water.
BRN 
609764
InChI
InChI=1S/C12H26N2O4/c1-5-15-9-10-17-7-3-14-4-8-18-12-11-16-6-2-13-1/h13-14H,1-12H2
InChIKey
NLMDJJTUQPXZFG-UHFFFAOYSA-N
SMILES
O1CCNCCOCCOCCNCCOCC1
CAS DataBase Reference
23978-55-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-37
WGK Germany 
2
RTECS 
HM1650000
F 
10
HS Code 
2934 99 90
Toxicity
LD50 orally in Rabbit: 3400 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.10953
Product name
Kryptofix® 22
Purity
for synthesis
Packaging
1g
Price
$93.6
Updated
2025/07/31
Sigma-Aldrich
Product number
8.10953
Product name
Kryptofix® 22
Purity
for synthesis
Packaging
5G
Price
$299
Updated
2025/07/31
Sigma-Aldrich
Product number
295809
Product name
1,4,10,13-Tetraoxa-7,16-diazacyclooctadecane
Purity
≥96%
Packaging
1g
Price
$282
Updated
2025/07/31
TCI Chemical
Product number
D2323
Product name
4,13-Diaza-18-crown 6-Ether
Purity
>98.0%(T)
Packaging
1g
Price
$158
Updated
2025/07/31
TCI Chemical
Product number
D2323
Product name
4,13-Diaza-18-crown 6-Ether
Purity
>98.0%(T)
Packaging
5g
Price
$597
Updated
2025/07/31
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4,13-Diaza-18-crown 6-ether Chemical Properties,Usage,Production

Chemical Properties

off-white shiny crystalline powder

Uses

1,4,10,13-Tetraoxa-7,16-diazacyclooctadecane is a crown ether, which can be used:

  • In the spectroscopic studies of its complex-forming reaction with iodine.
  • To prepare the ligand 7,16-bis(5-t-butyl-2-hydroxybenzyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane.
  • As a ligand in the study of zirconium facilitated hydrolysis of a dipeptide at neutral pH.

Purification Methods

Twice recrystallise it from *benzene/n-heptane, and dry it for 24hours under high vacuum [Weber & V.gtle Top Curr Chem (Springer Verlag, Berlin) 98 1 1981, D'Aprano & Sesta J Phys Chem 91 2415 1987].

4,13-Diaza-18-crown 6-ether Preparation Products And Raw materials

Raw materials

Preparation Products

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4,13-Diaza-18-crown 6-ether Suppliers

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View Lastest Price from 4,13-Diaza-18-crown 6-ether manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
1,7,10,16-Tetraoxa-4,13-diazacyclooctadecane 23978-55-4
Price
US $0.00/g
Min. Order
5g
Purity
>95.00%
Supply Ability
5g
Release date
2024-04-01
Zhuozhou Wenxi import and Export Co., Ltd
Product
1,7,10,16-Tetraoxa-4,13-diazacyclooctadecane 23978-55-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
1,7,10,16-Tetraoxa-4,13-diazacyclooctadecane 23978-55-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

23978-55-4, 4,13-Diaza-18-crown 6-etherRelated Search:

4,13-Diaza-18-crown 6-ether 7,16-Bis(carboxymethyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane 7,16-(Ethyleneoxyethylene)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane,7,16-(Oxybisethylene)(1,4,10,13-tetraoxa-7,16-diazacyclooctadecane) 7,16-(3,6-Dioxaoctane-1,8-diyl)(1,4,10,13-tetraoxa-7,16-diazacyclooctadecane),7,16-[Ethylenebis(oxyethylene)](1,4,10,13-tetraoxa-7,16-diazacyclooctadecane) 4-(Chloromethyl)styrene homopolymer Isobutyl iodide 18-Crown-6 1,4,7,10,13-PENTAOXA-16-AZACYCLOOCTADECANE Octadecane 7,16-DIBENZYL-1,4,10,13-TETRAOXA-7,16-DIAZACYCLOOCTADECANE,N,N'-DIBENZYL-1,4,10,13-TETRAOXA-7,16-DIAZACYCLOOCTADECANE PBFI-AM 1,4,10,13-Tetraoxa-7,16-diazacyclooctadecane, 7,16-didecyl- 5,6-BENZO-4,7,13,16,21,24-HEXAOXA-1,10-DIAZABICYCLO[8.8.8]HEXACOS-5-ENE N,N'-BIS(METHOXYMETHYL)DIAZA-18-CROWN-6 2-Decyl[7,16-(oxybisethylene)(1,4,10,13-tetraoxa-7,16-diazacyclooctadecane)] 4,4μ-[1,4,10,13-Tetraoxa-7,16-diazacyclooctadecane-7,16-diylbis(5-methoxy-6,2-benzofurandiyl)]bis-1,3-benzenedicarboxylic acid 1,10-Bis(methoxymethyl)-1,10-diaza-4,7,13,16-tetraoxacyclooctadecane 7,16-bis(4-methoxybenzyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane

  • 1,4,10,13-TETRAOXA-7,16-DIAZACYCLOOCTADECANE
  • KRYPTOFIX 22 POLYMER (SILICA GEL) FOR SYNTHESIS
  • Diaza-18-crown-6,98%
  • Diaza-18-crown-6, 98% 500MG
  • KRYPTOFIX 22 FOR SYNTHESIS
  • 4,13-DIAZA-18-CROWN-6
  • 7,16-DIAZA-18-CROWN-6
  • CAS_23978-55-4
  • DIAZA-18-CROWN-6
  • 1,4,10,13-TETRAOXA-7,16-DIAZACYCLOOCTADECANE, >=96%
  • KRYPTOFIX 22 POLYMER FOR SYNTHESIS
  • KRYPTOFIX 22 99+%
  • 1,10-diaza-4,7,13,16-tetraoxacyclooctadecane
  • 1,4,10,13-Tetraoza-7,16-diazacyclooctadecane
  • 4,7,13,16-Tetraoxa-1,10-diazacyclo octadecane
  • 7,16-diaza-1,4,10,13-tetraoxcyclooctadecane
  • cryptand2.2
  • cryptand22
  • KRYPTOFIX(R) 22
  • KRYPTOFIX(R) 22 POLYMER
  • KRYPTOFIX 22
  • KRYPTOFIX 22 POLYMER
  • 4,13-Diaza-18-crown6-Ether&gt
  • KRYPTOFIX 22 FOR SYNTHESIS 1 G
  • KRYPTOFIX 22 FOR SYNTHESIS 5 G
  • 4,13-DIAZA-18-CROWN 6-ETHER
  • 1,10-DIAZA-18-CROWN-6
  • 1,7,10,16-TETRAOXA-4,13-DIAZACYCLOOCTADECANE
  • Kryptofix<sup>?</sup> 22
  • 1,4,10,13-Tetraoxa-7,16-diazacyclooctadecane - [T94488]
  • 23978-55-4
  • C12H26N2O4
  • Crown Ethers
  • Azacrown Ethers
  • Macrocycles for Host-Guest Chemistry
  • Chelation/Complexation Compounds
  • Synthetic Reagents
  • Azacrown Ethers
  • Crown Ethers
  • Functional Materials
  • Macrocycles for Host-Guest Chemistry