ChemicalBook > CAS DataBase List > 1,1-Dibromoformaldoxime
1,1-Dibromoformaldoxime
- Product Name
- 1,1-Dibromoformaldoxime
- CAS No.
- 74213-24-4
- Chemical Name
- 1,1-Dibromoformaldoxime
- Synonyms
- hydroxycarbonimidic dibromide;DIBROMOFORMALDOXIME;dibromomethanone oxime;broMonitrile oxide;74213-24-4;1,1-DibromoformaL;1-Dibromoformaldoxime;1,1-DIBROMOFORMALDOXIME;Pyroxasulfone Impurity 2;1,1-Dibromoformaldoxime,95%
- CBNumber
- CB9261253
- Molecular Formula
- CHBr2NO
- Formula Weight
- 202.83
- MOL File
- 74213-24-4.mol
More
Less
1,1-Dibromoformaldoxime Property
- Melting point:
- 65-68 °C
- Boiling point:
- 230.0±23.0 °C(Predicted)
- Density
- 2.70±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- Chloroform (Very Slightly, Heated), Methanol
- form
- Solid
- pka
- 7.52±0.11(Predicted)
- color
- White to Dark Orange
- InChI
- InChI=1S/CHBr2NO/c2-1(3)4-5/h5H
- InChIKey
- AWBKQZSYNWLCMW-UHFFFAOYSA-N
- SMILES
- C(/Br)(\Br)=N/O
More
Less
Safety
- HS Code
- 2928009090
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P310Immediately call a POISON CENTER or doctor/physician.
More
Less
N-Bromosuccinimide Price
TRC
- Product number
- D425300
- Product name
- Dibromoformaldoxime
- Packaging
- 1g
- Price
- $45
- Updated
- 2021/12/16
TRC
- Product number
- D425300
- Product name
- Dibromoformaldoxime
- Packaging
- 10g
- Price
- $120
- Updated
- 2021/12/16
SynQuest Laboratories
- Product number
- 4147-9-00
- Product name
- 1,1-Dibromoformaldoxime
- Purity
- 95%
- Packaging
- 5G
- Price
- $101
- Updated
- 2021/12/16
Matrix Scientific
- Product number
- 069458
- Product name
- Dibromoformaldoxime
- Purity
- 96+%
- Packaging
- 25g
- Price
- $130
- Updated
- 2021/12/16
AK Scientific
- Product number
- J99808
- Product name
- 1,1-Dibromoformaldoxime
- Packaging
- 25g
- Price
- $130
- Updated
- 2021/12/16
More
Less
1,1-Dibromoformaldoxime Chemical Properties,Usage,Production
Uses
Dibromoformaldoxime is a reagent that undergoes cycloaddition with alkynes to prepare substituted 3-bromo-isoxazoles in high yield.
Synthesis Reference(s)
Tetrahedron Letters, 25, p. 387, 1984 DOI: 10.1016/S0040-4039(00)99890-3
Synthesis
298-12-4
74213-24-4
General procedure for the synthesis of 1,1-dibromoformaldehyde oxime from 2-oxoacetic acid: hydroxylamine hydrochloride (10 mmol) was added to a stirred aqueous (50 mL) solution of glyoxalic acid (10 mmol), and the reaction mixture was stirred for 24 hours at room temperature. Subsequently, sodium bicarbonate (20 mmol) was slowly added, followed by dichloromethane (60 mL). Bromine (1 mL) was added dropwise to the well-stirred two-phase mixture at 6 °C for 20 min. After the addition of bromine, stirring of the reaction mixture was continued for 3 hours. Upon completion of the reaction, the organic layer was separated and the aqueous layer was extracted with dichloromethane (50 mL). The organic extracts were combined, dried with magnesium sulfate, filtered and concentrated under reduced pressure. The residue was recrystallized with hexane (50 mL) to give 1.60 g (81% yield) of a white crystal product with a melting point of 65-66 °C (literature value 19: 63-65 °C).
References
[1] Tetrahedron Letters, 2015, vol. 56, # 13, p. 1635 - 1637
[2] EJNMMI Research, 2018, vol. 8,
[3] Angewandte Chemie - International Edition, 2017, vol. 56, # 13, p. 3703 - 3707
[4] Angew. Chem., 2017, vol. 129, # 13, p. 3757 - 3761,5
[5] Patent: WO2010/127978, 2010, A1. Location in patent: Page/Page column 51
1,1-Dibromoformaldoxime Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
1,1-Dibromoformaldoxime Suppliers
- Tel
- 181-3307-5798 18017383231
- 983544897@qq.com
- Country
- China
- ProdList
- 921
- Advantage
- 58
- Tel
- 13816002113
- Fax
- -
- 68249111@qq.com
- Country
- China
- ProdList
- 70
- Advantage
- 58
- Tel
- 18270980682
- Fax
- 021 51613951
- mlcheng@sunwaypharm.cn
- Country
- China
- ProdList
- 8669
- Advantage
- 57
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- +86-21-54098501
- Fax
- +86-21-54096319
- sales@sinch.com.cn
- Country
- China
- ProdList
- 11598
- Advantage
- 64
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9310
- Advantage
- 66
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11035
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- Fax
- E-Mail Inquiry
- info@syntechem.com
- Country
- China
- ProdList
- 12984
- Advantage
- 57
- Tel
- 18049974220
- Fax
- +86 (21) 51062076
- 3060526242@qq.com
- Country
- China
- ProdList
- 995
- Advantage
- 60
- Tel
- 021-54824098, 021-37212705 021-37212706, 13391256916
- Fax
- 021-54824069
- sales@chemzq.com
- Country
- China
- ProdList
- 570
- Advantage
- 55
- Tel
- 86-21-34053660
- Fax
- 86-21-34053661
- sale@labgogo.com
- Country
- China
- ProdList
- 9865
- Advantage
- 52
- Tel
- +86 943-8535351 13389336721
- Fax
- +86-943-8535351
- sales@chengzechem.com
- Country
- China
- ProdList
- 289
- Advantage
- 58
- Tel
- 025-66113011 17798518460
- Fax
- (1)02557626880
- cfzhang@aikonchem.com
- Country
- China
- ProdList
- 19913
- Advantage
- 55
- Tel
- 150-2103-5486 18017383231
- Fax
- qq：2817624287
- 983544897@qq.com
- Country
- China
- ProdList
- 9342
- Advantage
- 55
- Tel
- 021-54849683 13601642561
- Fax
- +86-21-54375689
- sales@keepontech.com
- Country
- China
- ProdList
- 998
- Advantage
- 59
- Tel
- +86 (21) 13764690794 657056093
- Fax
- +86 (21) 33321990
- sales@shfcchem.com
- Country
- China
- ProdList
- 95
- Advantage
- 58
- Tel
- 021-62960152
- Fax
- 021-52212593
- 934678158@qq.com
- Country
- China
- ProdList
- 9899
- Advantage
- 55
- Tel
- +86-021-50935922
- Fax
- +86-021-33847795
- Country
- China
- ProdList
- 7865
- Advantage
- 55
- Tel
- 023-89130144 18523560356
- Fax
- 023-67534737
- zhyong1011@163.com
- Country
- China
- ProdList
- 290
- Advantage
- 58
- Tel
- 021-67220633 021-54824098
- Fax
- +86-21-54824069
- chemfun@chemfun.net
- Country
- China
- ProdList
- 491
- Advantage
- 58
- Tel
- 021-24206007 13764915196
- Fax
- 86-021-23027023
- sales@balmxy.com
- Country
- China
- ProdList
- 6874
- Advantage
- 55
- Tel
- 0571-87396432
- Fax
- 0571-87396431
- sales@jhechem.com
- Country
- China
- ProdList
- 14912
- Advantage
- 59
- Tel
- 021-61478794
- Fax
- 021-61478794
- sales@hcshhai.com
- Country
- China
- ProdList
- 9793
- Advantage
- 50
- Tel
- 010-1234567 18521000990
- Fax
- 86-021-33275113
- sonyuanchemical@163.com
- Country
- China
- ProdList
- 6479
- Advantage
- 50
- Tel
- 021-60455363 18019463053
- Fax
- 50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12346
- Advantage
- 58
- Tel
- 21-65679720
- Fax
- 0086-21-5186 1128
- service@speedchemical.com
- Country
- China
- ProdList
- 604
- Advantage
- 55
- Tel
- 86-(0)21-31261262 373522135
- Fax
- 86-(0)21-33250524
- sales@novochemy.com
- Country
- China
- ProdList
- 6498
- Advantage
- 58
- Tel
- 021-64340559 13651849907;
- Fax
- 021- 64345308
- xinyu_shi@jwypharmlab.com.cn
- Country
- China
- ProdList
- 12000
- Advantage
- 58
- Tel
- 526763801 13301653310
- Fax
- +86-21-51619052
- 526763801@qq.com
- Country
- China
- ProdList
- 9274
- Advantage
- 55
- Tel
- 0371-86658258
- Fax
- 0371-60996044
- info@coreychem.com
- Country
- China
- ProdList
- 10453
- Advantage
- 58
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 0519-85528066 13775048983
- Fax
- 0519-85528066
- sales@hopschem.com
- Country
- China
- ProdList
- 31553
- Advantage
- 55
- Tel
- 025-83453382-8005
- Fax
- 025-83453382
- sale@parabiochem.com
- Country
- China
- ProdList
- 9595
- Advantage
- 55
- Tel
- 0371-55289822 18737195735
- Fax
- QQ：2370407954
- 2370407954@qq.com
- Country
- China
- ProdList
- 1981
- Advantage
- 55
- Tel
- 0-2022843681 15618226720
- Fax
- +86-21-51601218
- chaolaichem@foxmail.com
- Country
- China
- ProdList
- 12475
- Advantage
- 58
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 0371-55900031 18137872243
- Fax
- QQ：2853979815
- 2853979815@qq.com
- Country
- China
- ProdList
- 9975
- Advantage
- 55
- Tel
- 400-711-5280 86-571-81025280
- Fax
- 86-571-85806285
- sales@molcore.com
- Country
- China
- ProdList
- 9967
- Advantage
- 58
- Tel
- 0371-0371-86259281 15981966935
- Fax
- 0371-86259281
- jacschem@163.com
- Country
- China
- ProdList
- 2005
- Advantage
- 58
- Tel
- 86-0573-85866609 13325730825
- Fax
- 0573-85866609
- 945717149@qq.com
- Country
- China
- ProdList
- 8593
- Advantage
- 58
- Tel
- +86-（0）57185586718; +8613336195806
- Fax
- +86-571-85864795
- sales@capot.com
- Country
- China
- ProdList
- 29735
- Advantage
- 60
- Tel
- 13918479294
- Fax
- -
- xiebenfa@163.com
- Country
- China
- ProdList
- 4087
- Advantage
- 58
- Tel
- 13331045123
- Fax
- 86-10-80339217
- 2559355526@qq.com
- Country
- China
- ProdList
- 14193
- Advantage
- 58
- Tel
- 15981811963
- Fax
- QQ：1410472904
- 1410472904@qq.com
- Country
- China
- ProdList
- 5825
- Advantage
- 58
- Tel
- 13651987816
- Fax
- -
- hongminpharm@163.com
- Country
- China
- ProdList
- 2326
- Advantage
- 58
- Tel
- 021-000000 13917643586;
- admin@jingshipharmatech.com
- Country
- China
- ProdList
- 9856
- Advantage
- 58
More
Less
View Lastest Price from 1,1-Dibromoformaldoxime manufacturers
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- 1,1-Dibromoformaldoxime 74213-24-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
Career Henan Chemical Co
- Product
- 1,1-Dibromoformaldoxime 74213-24-4
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- JD 657
- Release date
- 2019-09-01