1H-Indole-3-ethanaMine, 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]Methyl]-

Product Name: 1H-Indole-3-ethanaMine, 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]Methyl]-
CAS No.: 467459-31-0
Chemical Name: 1H-Indole-3-ethanaMine, 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]Methyl]-
Synonyms: LU AE58054;LU AE58084;idalopirdine;LU AE58054(Idalopirdine);Idalopirdine(Lu-AE-58054);idalopirdine, 10 mM in DMSO;IDALOPIRDINE;LU AE 58054;LUAE58054;LU AE58054 HYDROCHLORIDE; LU AE 58054 HYDROCHLORIDE;N-[2-(6-Fluoro-1H-indol-3-yl)ethyl]-3-(2,2,3,3-tetrafluoropropoxy)benzylamine;6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]methyl]-1H-Indole-3-ethanamine
CBNumber: CB92625336
Molecular Formula: C20H19F5N2O
Formula Weight: 398.37
MOL File: 467459-31-0.mol

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1H-Indole-3-ethanaMine, 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]Methyl]- Property

Boiling point:: 500.9±50.0 °C(Predicted)
Density: 1.309±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: 25℃: DMSO
form: Powder
pka: 16.63±0.30(Predicted)
color: white to beige

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 27335
Product name: LU AE58054
Packaging: 100mg
Price: $547
Updated: 2024/03/01

Cayman Chemical

Product number: 27335
Product name: LU AE58054
Packaging: 250mg
Price: $1139
Updated: 2024/03/01

Cayman Chemical

Product number: 27335
Product name: LU AE58054
Packaging: 25mg
Price: $153
Updated: 2024/03/01

Cayman Chemical

Product number: 27335
Product name: LU AE58054
Packaging: 50mg
Price: $290
Updated: 2024/03/01

Usbiological

Product number: 453947
Product name: Lu AE58054
Packaging: 5mg
Price: $355
Updated: 2021/12/16

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1H-Indole-3-ethanaMine, 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]Methyl]- Chemical Properties,Usage,Production

Uses

The selective and high affinity 5-?HT6 receptor antagonist Lu AE58054 as promising treatment for cognitive disorders, in particular for Alzheimer’s disease (AD).

Biological Activity

Idalopirdine (Lu AE58054) is an orally available, and potent antagonist of the serotonin 6 (5-HT6) receptor. Idalopirdine has been reported to be highly selective over other G-protein coupled receptors. It has K(d) of 0.2nM for the 5-HT6 receptor with 16-fold selectivity over the 5-HT2A receptor (K(i) 3.2nM) and >100-fold selectivity to all other evaluated targets.

1H-Indole-3-ethanaMine, 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]Methyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-Indole-3-ethanaMine, 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]Methyl]- Suppliers

China 67 France 1 United Kingdom 1 United States 10 Global 79

Shanghai Boyle Chemical Co., Ltd.

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View Lastest Price from 1H-Indole-3-ethanaMine, 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]Methyl]- manufacturers

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.

Product: Lu Ae58054 467459-31-0
Price: US $0.00/g
Min. Order: 1g
Purity: More Than 99%
Supply Ability: 100kg/Month
Release date: 2024-11-13

Career Henan Chemical Co

Product: 2-(6-fluoro-1H-indol-3-yl)-N-[[3-(2,2,3,3-tetrafluoropropoxy)phen yl]methyl]ethanamine 467459-31-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98% HPLC
Supply Ability: g/kg/ton
Release date: 2019-12-23

Career Henan Chemical Co

Product: Lu AE58054 467459-31-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98% HPLC
Supply Ability: g/kg/ton
Release date: 2019-12-20

467459-31-0, 1H-Indole-3-ethanaMine, 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]Methyl]-Related Search:

LUTETIUM

LU AE58054

N-[2-(6-Fluoro-1H-indol-3-yl)ethyl]-3-(2,2,3,3-tetrafluoropropoxy)benzylamine

6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]methyl]-1H-Indole-3-ethanamine

idalopirdine

LU AE58084

LU AE58054(Idalopirdine)

1H-Indole-3-ethanaMine, 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]Methyl]-

Idalopirdine(Lu-AE-58054)

LU AE58054 HYDROCHLORIDE; LU AE 58054 HYDROCHLORIDE

2-(6-fluoro-1H-indol-3-yl)-N-[[3-(2,2,3,3-tetrafluoropropoxy)phen yl]methyl]ethanamine

IDALOPIRDINE;LU AE 58054;LUAE58054

5-HT Receptor,Serotonin Receptor,Lu AE-58054,idalopirdine,Inhibitor,inhibit,5-hydroxytryptamine Receptor,Lu AE 58054

idalopirdine, 10 mM in DMSO

467459-31-0

C20H19F5N2O