Letermovir (AIC246)

Product Name: Letermovir (AIC246)
CAS No.: 917389-32-3
Chemical Name: Letermovir (AIC246)
Synonyms: Lettmove;AIC246;MK-8828;CS-2799;Letemovir;LeterMovir;Letermovlr;Lertemovir;D3-Letermovir;LeterMovir-005
CBNumber: CB92627305
Molecular Formula: C29H28F4N4O4
Formula Weight: 572.55
MOL File: 917389-32-3.mol

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Letermovir (AIC246) Property

Boiling point:: 706.5±70.0 °C(Predicted)
Density: 1.37±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: ≥57.3 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form: solid
pka: 4.00±0.10(Predicted)
color: Off-white to yellow
InChIKey: FWYSMLBETOMXAG-QHCPKHFHSA-N
SMILES: N1C2=C(C=CC=C2F)[C@H](CC(O)=O)N(C2=CC(C(F)(F)F)=CC=C2OC)C=1N1CCN(C2=CC=CC(OC)=C2)CC1

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Safety

WGK Germany: WGK 3
Storage Class: 11 - Combustible Solids
Hazard Classifications: Repr. 2
STOT RE 2 Oral

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P314Get medical advice/attention if you feel unwell.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML3891
Product name: Letermovir
Purity: ≥98% (HPLC)
Packaging: 5 mg
Price: $197
Updated: 2026/04/30

Sigma-Aldrich

Product number: SML3891
Product name: Letermovir
Purity: ≥98% (HPLC)
Packaging: 25 mg
Price: $793
Updated: 2026/04/30

Cayman Chemical

Product number: 17556
Product name: Letermovir
Purity: ≥98%
Packaging: 1mg
Price: $81
Updated: 2026/04/30

Cayman Chemical

Product number: 17556
Product name: Letermovir
Purity: ≥98%
Packaging: 5mg
Price: $357
Updated: 2026/04/30

Cayman Chemical

Product number: 17556
Product name: Letermovir
Purity: ≥98%
Packaging: 10mg
Price: $553
Updated: 2026/04/30

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Letermovir (AIC246) Chemical Properties,Usage,Production

Uses

Letermovir acts as an orally or i.v administered cytomegalovirus terminus complex inhibitor, antiviral agent, used in the treatment of CMV infection which is prevalent in those with immunocompromised systems.

Biological Activity

Letermovir (AIC246) is an orally active, potent and selective human cytomegalovirus (HCMV) DNA terminase complex inhibitor th at blocks HCMV replication (EC50 = 0.9-3.1 nM among 17 clinial HCMV isolates; EC50 = 1.6-3.9 nM against 6 AD169-derived drug-resistant variants) by interfering with viral DNA cleavage/packaging. Letermovir exhibits little potency toward MCMV (Smith), RCMV (Maastricht), VZV (Oka), HSV-1 (166v VP22-GFP), HSV-2 (01-6332), HHV-6 (typeA-GS) or EBV (B95-8) (MCMV EC50 = 4.5 μM, all other EC50 >10 μM).

in vivo

Letermovir (10-100 mg/kg/day, p.o.) leads to a dose-dependent reduction of the HCMV titer in transplanted cells compared to that of the placebo-treated control group using the mouse xenograft model^[3].

Letermovir (AIC246) Preparation Products And Raw materials

Raw materials

Preparation Products

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Letermovir (AIC246) Suppliers

China 252 India 5 United Kingdom 1 United States 11 Global 269

CHENGHUI PHARMACEUTICAL GROUP LTD

Tel: 053158897070 15550412551
Fax: 0531-58897046
Email: market@jnchsd.com
Country: China
ProdList: 230
Advantage: 58

Hangzhou Runyan Medical Technology Co., LTD

Tel: 571-13989459766 18112526015
Email: sales@runyanpharma.com
Country: China
ProdList: 497
Advantage: 58

Jinan Guoding Pharmaceutical Technology Co., Ltd.

Tel: 053167801621 15628878003
Fax: 053167801621
Email: sales@guodingpharma.com
Country: China
ProdList: 467
Advantage: 58

Taizhou Yuxin Biotechnology Co., Ltd.,

Tel: +86-0576--88902229 +86-13968687450
Email: yuxin@yuxchem.com
Country: China
ProdList: 262
Advantage: 58

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4769
Advantage: 55

NANJING ZENJI PHARMACEUTICALS

Tel: 0512-62750571
Email: marketing@zenjipharma.com
Country: China
ProdList: 421
Advantage: 58

Jinan Chenghui Shuangda biological Co., LTD

Tel: 053158897070 15550412551
Fax: 0531-58897003
Email: market@jnchsd.com
Country: China
ProdList: 218
Advantage: 62

YICHANG TIANRUI BIOPHARM CO., LTD

Tel: 13469840438
Email: caiweiguo@renfu.com.cn
Country: China
ProdList: 48
Advantage: 58

Shandong Mingfeng Pharmaceutical and Technology Co. Ltd

Tel: 053155551677 15315114555
Fax: QQ:1345456643
Email: 1345456643@qq.com
Country: China
ProdList: 275
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

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View Lastest Price from Letermovir (AIC246) manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd

Product: LeterMovir 917389-32-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: Customise
Release date: 2025-11-26

Wuhan Biocar Pharmacy CO.,Ltd.

Product: LeterMovir 917389-32-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 580kg
Release date: 2025-02-24

Strong peptide cross-border e-commerce Co. LTD

Product: LeterMovir 917389-32-3
Price: US $40.00-35.00/box
Min. Order: 1box
Purity: 99.9+
Supply Ability: 2000box
Release date: 2024-06-07

917389-32-3, Letermovir (AIC246)Related Search:

2-Propenoic acid, 3-[3-fluoro-2-[[[[2-methoxy-5-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenyl]-, methyl ester, (2E)- 2-Propenoic acid, 3-[3-fluoro-2-[[[4-(3-methoxyphenyl)-1-piperazinyl][[2-methoxy-5-(trifluoromethyl)phenyl]imino]methyl]amino]phenyl]-, methyl ester, (2E)- Bortezomib

AIC246

LeterMovir

(4S)-8-Fluoro-3,4-dihydro-2-[4-(3-methoxyphenyl)-1-piperazinyl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4-quinazolineacetic acid

AIC246;AIC 246;AIC-246

CS-2799

4-Quinazolineacetic acid, 8-fluoro-3,4-dihydro-2-[4-(3-methoxyphenyl)-1-piperazinyl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-, (4S)-

Letermovir (AIC246)

MK-8828

LeterMovir-005

Lettmove

methyl(S)-2-(8-fluoro-3-(2-methoxy-5-(trifluoromethyl)phenyl)-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3,4-dihydroquinazolin-4-yl)acetate

Letermovir-d6Q: What is Letermovir-d6 Q: What is the CAS Number of Letermovir-d6

LetermovirQ: What is Letermovir Q: What is the CAS Number of Letermovir

(S)-2-(8-Fluoro-3-(2-methoxy-5-(trifluoromethyl)phenyl)-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3,4-dihydroquinazolin-4-yl)acetic acid

Letermovlr

LeterMovir Impurity 27

Cilnidipine Impurity 29

Letermovir, 10 mM in DMSO

Letemovir

(S)-{8-fluoro-2-[4-(3-methoxyphenyl)piperazine-1-yl]-3-(2-methoxy-5-trifluoromethylphenyl)-3,4-dihydroquinazoline-4-yl}acetic acid

D3-Letermovir

2-[(4S)-8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4H-quinazolin-4-yl]acetic acid

Lertemovir

917389-32-3

1616761-00-3

C29H28F4N4O4

API

917389-32-3