LeterMovir
- Product Name
- LeterMovir
- CAS No.
- 917389-32-3
- Chemical Name
- LeterMovir
- Synonyms
- Lettmove;AIC246;MK-8828;CS-2799;LeterMovir;Letermovlr;LeterMovir-005;Letermovir (AIC246);AIC246;AIC 246;AIC-246;LeterMovir Impurity 27
- CBNumber
- CB92627305
- Molecular Formula
- C29H28F4N4O4
- Formula Weight
- 572.55
- MOL File
- 917389-32-3.mol
LeterMovir Property
- Boiling point:
- 706.5±70.0 °C(Predicted)
- Density
- 1.37±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- ≥57.3 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
- form
- solid
- pka
- 4.00±0.10(Predicted)
- color
- Off-white to yellow
- InChI
- InChI=1S/C29H28F4N4O4/c1-40-20-6-3-5-19(16-20)35-11-13-36(14-12-35)28-34-27-21(7-4-8-22(27)30)23(17-26(38)39)37(28)24-15-18(29(31,32)33)9-10-25(24)41-2/h3-10,15-16,23H,11-14,17H2,1-2H3,(H,38,39)/t23-/m0/s1
- InChIKey
- FWYSMLBETOMXAG-QHCPKHFHSA-N
- SMILES
- N1C2=C(C=CC=C2F)[C@H](CC(O)=O)N(C2=CC(C(F)(F)F)=CC=C2OC)C=1N1CCN(C2=CC=CC(OC)=C2)CC1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H361Suspected of damaging fertility or the unborn child
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P281Use personal protective equipment as required.
P308+P313IF exposed or concerned: Get medical advice/attention.
P314Get medical advice/attention if you feel unwell.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 17556
- Product name
- Letermovir
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $73
- Updated
- 2024/03/01
- Product number
- 17556
- Product name
- Letermovir
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $324
- Updated
- 2024/03/01
- Product number
- 17556
- Product name
- Letermovir
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $502
- Updated
- 2024/03/01
- Product number
- L321005
- Product name
- Letermovir
- Packaging
- 25mg
- Price
- $940
- Updated
- 2021/12/16
- Product number
- 453640
- Product name
- Letermovir
- Packaging
- 2.5mg
- Price
- $496
- Updated
- 2021/12/16
LeterMovir Chemical Properties,Usage,Production
Uses
Letermovir acts as an orally or i.v administered cytomegalovirus terminus complex inhibitor, antiviral agent, used in the treatment of CMV infection which is prevalent in those with immunocompromised systems.
Biological Activity
Letermovir (AIC246) is an orally active, potent and selective human cytomegalovirus (HCMV) DNA terminase complex inhibitor th at blocks HCMV replication (EC50 = 0.9-3.1 nM among 17 clinial HCMV isolates; EC50 = 1.6-3.9 nM against 6 AD169-derived drug-resistant variants) by interfering with viral DNA cleavage/packaging. Letermovir exhibits little potency toward MCMV (Smith), RCMV (Maastricht), VZV (Oka), HSV-1 (166v VP22-GFP), HSV-2 (01-6332), HHV-6 (typeA-GS) or EBV (B95-8) (MCMV EC50 = 4.5 μM, all other EC50 >10 μM).
LeterMovir Preparation Products And Raw materials
Raw materials
Preparation Products
LeterMovir Suppliers
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- 0531-58897070 15254140813
- Fax
- 0531-58897046
- market@jnchsd.com
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- China
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- 13989459766 17767198890
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- China
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- 053167801621 13153106106
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- 053167801621
- sales@guodingpharma.com
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- China
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- +86-0576--88902229 +86-13968687450
- yuxin@yuxchem.com
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- China
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- 020-39119399 18927568969
- Fax
- 020-39119999
- isunpharm@qq.com
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- China
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- 4674
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- Tel
- 025-58231105-8151 15190133791;
- marketing@zenjipharma.com
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- China
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- 0531-58897003 15550412551
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- 0531-58897003
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- China
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- 18671799682
- caiweiguo@renfu.com.cn
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- China
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- 18679828511
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- China
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- Tel
- Fax
- 86-21-57758967
- sales@boylechem.com
- Country
- China
- ProdList
- 2922
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- 55
View Lastest Price from LeterMovir manufacturers
- Product
- LeterMovir 917389-32-3
- Price
- US $40.00-35.00/box
- Min. Order
- 1box
- Purity
- 99.9+
- Supply Ability
- 2000box
- Release date
- 2024-06-07
- Product
- LeterMovir 917389-32-3
- Price
- US $40.00-35.00/box
- Min. Order
- 1box
- Purity
- 99.9+
- Supply Ability
- 2000box
- Release date
- 2024-06-07
- Product
- LeterMovir 917389-32-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98
- Supply Ability
- 1000
- Release date
- 2025-01-03