LeterMovir

Product Name: LeterMovir
CAS No.: 917389-32-3
Chemical Name: LeterMovir
Synonyms: Lettmove;AIC246;MK-8828;CS-2799;Letemovir;LeterMovir;Letermovlr;D3-Letermovir;LeterMovir-005;Letermovir (AIC246)
CBNumber: CB92627305
Molecular Formula: C29H28F4N4O4
Formula Weight: 572.55
MOL File: 917389-32-3.mol

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LeterMovir Property

Boiling point:: 706.5±70.0 °C(Predicted)
Density: 1.37±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: ≥57.3 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form: solid
pka: 4.00±0.10(Predicted)
color: Off-white to yellow
InChI: InChI=1S/C29H28F4N4O4/c1-40-20-6-3-5-19(16-20)35-11-13-36(14-12-35)28-34-27-21(7-4-8-22(27)30)23(17-26(38)39)37(28)24-15-18(29(31,32)33)9-10-25(24)41-2/h3-10,15-16,23H,11-14,17H2,1-2H3,(H,38,39)/t23-/m0/s1
InChIKey: FWYSMLBETOMXAG-QHCPKHFHSA-N
SMILES: N1C2=C(C=CC=C2F)[C@H](CC(O)=O)N(C2=CC(C(F)(F)F)=CC=C2OC)C=1N1CCN(C2=CC=CC(OC)=C2)CC1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P314Get medical advice/attention if you feel unwell.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML3891
Product name: Letermovir
Purity: ≥98% (HPLC)
Packaging: 5 mg
Price: $174.8
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML3891
Product name: Letermovir
Purity: ≥98% (HPLC)
Packaging: 25 mg
Price: $739
Updated: 2025/07/31

Cayman Chemical

Product number: 17556
Product name: Letermovir
Purity: ≥98%
Packaging: 1mg
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 17556
Product name: Letermovir
Purity: ≥98%
Packaging: 5mg
Price: $324
Updated: 2024/03/01

Cayman Chemical

Product number: 17556
Product name: Letermovir
Purity: ≥98%
Packaging: 10mg
Price: $502
Updated: 2024/03/01

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LeterMovir Chemical Properties,Usage,Production

Uses

Letermovir acts as an orally or i.v administered cytomegalovirus terminus complex inhibitor, antiviral agent, used in the treatment of CMV infection which is prevalent in those with immunocompromised systems.

Biological Activity

Letermovir (AIC246) is an orally active, potent and selective human cytomegalovirus (HCMV) DNA terminase complex inhibitor th at blocks HCMV replication (EC50 = 0.9-3.1 nM among 17 clinial HCMV isolates; EC50 = 1.6-3.9 nM against 6 AD169-derived drug-resistant variants) by interfering with viral DNA cleavage/packaging. Letermovir exhibits little potency toward MCMV (Smith), RCMV (Maastricht), VZV (Oka), HSV-1 (166v VP22-GFP), HSV-2 (01-6332), HHV-6 (typeA-GS) or EBV (B95-8) (MCMV EC50 = 4.5 μM, all other EC50 >10 μM).

in vivo

Letermovir (10-100 mg/kg/day, p.o.) leads to a dose-dependent reduction of the HCMV titer in transplanted cells compared to that of the placebo-treated control group using the mouse xenograft model^[3].

LeterMovir Preparation Products And Raw materials

Raw materials

Preparation Products

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LeterMovir Suppliers

China 242 India 5 United Kingdom 1 United States 11 Global 259

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19552
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

Protheragen-ING

Tel: +16313385890
Email: info@protheragen-ing.com
Country: United States
ProdList: 3868
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354;
Email: support@targetmol.com
Country: United States
ProdList: 39035
Advantage: 58

ApexBio Technology

Tel: --
Fax: --
Email: sales@apexbt.com
Country: United States
ProdList: 6251
Advantage: 58

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

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View Lastest Price from LeterMovir manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd

Product: LeterMovir 917389-32-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: Customise
Release date: 2025-11-26

Wuhan Biocar Pharmacy CO.,Ltd.

Product: LeterMovir 917389-32-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 580kg
Release date: 2025-02-24

Strong peptide cross-border e-commerce Co. LTD

Product: LeterMovir 917389-32-3
Price: US $40.00-35.00/box
Min. Order: 1box
Purity: 99.9+
Supply Ability: 2000box
Release date: 2024-06-07

917389-32-3, LeterMovirRelated Search:

2-Propenoic acid, 3-[3-fluoro-2-[[[[2-methoxy-5-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenyl]-, methyl ester, (2E)- 2-Propenoic acid, 3-[3-fluoro-2-[[[4-(3-methoxyphenyl)-1-piperazinyl][[2-methoxy-5-(trifluoromethyl)phenyl]imino]methyl]amino]phenyl]-, methyl ester, (2E)- Bortezomib

AIC246

LeterMovir

(4S)-8-Fluoro-3,4-dihydro-2-[4-(3-methoxyphenyl)-1-piperazinyl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4-quinazolineacetic acid

AIC246;AIC 246;AIC-246

CS-2799

4-Quinazolineacetic acid, 8-fluoro-3,4-dihydro-2-[4-(3-methoxyphenyl)-1-piperazinyl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-, (4S)-

Letermovir (AIC246)

MK-8828

LeterMovir-005

Lettmove

methyl(S)-2-(8-fluoro-3-(2-methoxy-5-(trifluoromethyl)phenyl)-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3,4-dihydroquinazolin-4-yl)acetate

Letermovir-d6Q: What is Letermovir-d6 Q: What is the CAS Number of Letermovir-d6

LetermovirQ: What is Letermovir Q: What is the CAS Number of Letermovir

(S)-2-(8-Fluoro-3-(2-methoxy-5-(trifluoromethyl)phenyl)-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3,4-dihydroquinazolin-4-yl)acetic acid

Letermovlr

LeterMovir Impurity 27

Cilnidipine Impurity 29

Letermovir, 10 mM in DMSO

Letemovir

(S)-{8-fluoro-2-[4-(3-methoxyphenyl)piperazine-1-yl]-3-(2-methoxy-5-trifluoromethylphenyl)-3,4-dihydroquinazoline-4-yl}acetic acid

D3-Letermovir

917389-32-3

1616761-00-3

C29H28F4N4O4

API

917389-32-3