1-(4-thio-beta-D-ribofuranosyl)uracil

Product Name: 1-(4-thio-beta-D-ribofuranosyl)uracil
CAS No.: 6741-73-7
Chemical Name: 1-(4-thio-beta-D-ribofuranosyl)uracil
Synonyms: 4’-Thiouridine;1-(4-thio-β-D-ribofuranosyl)uracil;1-(4-thio-beta-D-ribofuranosyl)uracil;4’-Thiouridine, 1-(4-Thio-beta-D-ribofuranosyl)uracil;1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl)pyrimidine-2,4(1H,3H)-dione
CBNumber: CB92630824
Molecular Formula: C9H12N2O5S
Formula Weight: 260.27
MOL File: 6741-73-7.mol

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1-(4-thio-beta-D-ribofuranosyl)uracil Property

Melting point:: 195-196 °C(Solv: chloroform (67-66-3); ethanol (64-17-5))
Density: 1.687±0.06 g/cm3(Predicted)
pka: 9.39±0.10(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Chemenu

Product number: CM167832
Product name: 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl)pyrimidine-2,4(1H,3H)-dione
Purity: 97%
Packaging: 100mg
Price: $526
Updated: 2021/12/16

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1-(4-thio-beta-D-ribofuranosyl)uracil Chemical Properties,Usage,Production

Uses

4′-Thiouridine (1-(4-thio-beta-D-ribofuranosyl)uracil) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

1-(4-thio-beta-D-ribofuranosyl)uracil Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(4-thio-beta-D-ribofuranosyl)uracil Suppliers

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6741-73-7, 1-(4-thio-beta-D-ribofuranosyl)uracilRelated Search:

1-(4-thio-beta-D-ribofuranosyl)uracil

1-(4-thio-β-D-ribofuranosyl)uracil

1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl)pyrimidine-2,4(1H,3H)-dione

4’-Thiouridine, 1-(4-Thio-beta-D-ribofuranosyl)uracil

4’-Thiouridine

6741-73-7