1,1-Cyclobutanedicarboxylic acid, 3-oxo-, 1,1-bis(1-methylethyl) ester
- Product Name
- 1,1-Cyclobutanedicarboxylic acid, 3-oxo-, 1,1-bis(1-methylethyl) ester
- CAS No.
- 893724-10-2
- Chemical Name
- 1,1-Cyclobutanedicarboxylic acid, 3-oxo-, 1,1-bis(1-methylethyl) ester
- Synonyms
- Diisopropyl 3-oxocyclobutane-1,1-dicarboxylate;3-Oxo-cyclobutane-1,1-dic...;Diisopropyl 3-oxocyclobutane-1,1-dicaboxylate;dipropan-2-yl 3-oxocyclobutane-1,1-dicarboxylate;1,1-bis(propan-2-yl) 3-oxocyclobutane-1,1-dicarboxylate;3-Oxo-cyclobutane-1,1-dicarboxylic acid diisopropyl ester;1,1-Cyclobutanedicarboxylic acid, 3-oxo-, 1,1-bis(1-methylethyl) ester
- CBNumber
- CB92631982
- Molecular Formula
- C12H18O5
- Formula Weight
- 242.27
- MOL File
- 893724-10-2.mol
1,1-Cyclobutanedicarboxylic acid, 3-oxo-, 1,1-bis(1-methylethyl) ester Property
- Boiling point:
- 293.2±40.0 °C(Predicted)
- Density
- 1.165±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
Safety
- HS Code
- 2918999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- O849803
- Product name
- 3-Oxo-cyclobutane-1,1-dicarboxylicAcidDiisopropylEster
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 1474AL
- Product name
- 1,1-Bis(propan-2-yl)3-oxocyclobutane-1,1-dicarboxylate
- Packaging
- 1g
- Price
- $21
- Updated
- 2021/12/16
- Product number
- 2229-1-33
- Product name
- 3-Oxocyclobutane-1,1-dicarboxylic acid, diisopropyl ester
- Packaging
- 250mg
- Price
- $28
- Updated
- 2021/12/16
- Product number
- 2229-1-33
- Product name
- 3-Oxocyclobutane-1,1-dicarboxylic acid, diisopropyl ester
- Packaging
- 1g
- Price
- $83
- Updated
- 2021/12/16
- Product number
- 112928
- Product name
- 3-Oxo-cyclobutane-1,1-dicarboxylic acid diisopropyl ester
- Packaging
- 1g
- Price
- $85
- Updated
- 2021/12/16
1,1-Cyclobutanedicarboxylic acid, 3-oxo-, 1,1-bis(1-methylethyl) ester Chemical Properties,Usage,Production
Synthesis
115118-68-8
893724-10-2
General procedure for the synthesis of diisopropyl 3-oxocyclobutane-1,1-dicarboxylate from diisopropyl 3,3-dimethoxycyclobutane-1,1-dicarboxylate: in a round-bottomed flask containing a solution of 3,3-dimethoxycyclobutane-1,1-dicarboxylic acid diisopropyl 3,3-dimethoxycyclobutane-1,1-dicarboxylate (1.5 g, 5.20 mmol) in dichloromethane (20 mL), trifluoroacetic acid (2 mL, 26.0 mmol). The reaction mixture was stirred at room temperature for 2.5 hours. After the reaction was completed, the reaction mixture was diluted with ethyl acetate. The organic phase was washed sequentially with water, saturated sodium bicarbonate solution and brine. The organic phase was dried with anhydrous sodium sulfate, filtered and concentrated to give diisopropyl 3-oxocyclobutane-1,1-dicarboxylate (1.2 g). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 5.13 (dt, J = 12.5, 6.3 Hz, 2H), 3.64-3.53 (m, 4H), 1.32-1.24 (m, 12H).
References
[1] Synlett, 2009, # 11, p. 1827 - 1829
[2] Synlett, 2014, vol. 25, # 3, p. 355 - 358
[3] RSC Advances, 2016, vol. 6, # 27, p. 22737 - 22748
[4] Patent: US2009/233903, 2009, A1. Location in patent: Page/Page column 52
[5] Patent: WO2015/5901, 2015, A1. Location in patent: Page/Page column 702
1,1-Cyclobutanedicarboxylic acid, 3-oxo-, 1,1-bis(1-methylethyl) ester Preparation Products And Raw materials
Raw materials
Preparation Products
1,1-Cyclobutanedicarboxylic acid, 3-oxo-, 1,1-bis(1-methylethyl) ester Suppliers
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11035
- Advantage
- 64
- Tel
- 150-2103-5486 18017383231
- Fax
- qq：2817624287
- 983544897@qq.com
- Country
- China
- ProdList
- 9342
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- Fax
- -
- eric_feng1954@126.com
- Country
- China
- ProdList
- 9248
- Advantage
- 55
- Tel
- 515-88280676 18921872653
- sales@ximanbio.com
- Country
- China
- ProdList
- 1524
- Advantage
- 56
- Tel
- 0371-53765687 18937137882
- Fax
- QQ:2885373884
- 2853979813@qq.com
- Country
- China
- ProdList
- 7991
- Advantage
- 55
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 025-58859352 18068836627
- Fax
- 02557626880
- sales01@aikonchem.com
- Country
- China
- ProdList
- 16027
- Advantage
- 58
View Lastest Price from 1,1-Cyclobutanedicarboxylic acid, 3-oxo-, 1,1-bis(1-methylethyl) ester manufacturers
- Product
- 3-Oxo-cyclobutane-1,1-dic... 893724-10-2
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 85.0-99.8%
- Supply Ability
- 20 tons
- Release date
- 2020-11-12