RAS-2410 hydrochloride

Product Name: RAS-2410 hydrochloride
CAS No.: 1187075-34-8
Chemical Name: RAS-2410 hydrochloride
Synonyms: Resminostat HCl;RAS2410 hydrochloride;4SC-201 hydrochloride;RAS-2410 hydrochloride;RAS 2410 hydrochloride;ResMinostat (hydrochloride);Resminostat hydrochloride (4SC-201);RAS2410; 4SC-201; RAS 2410; RAS-2410;4SC201;4SC 201;RAS2410 HYDROCHLORIDE; 4SC-201 HYDROCHLORIDE; RAS 2410 HYDROCHLORIDE; RAS-2410 HYDROCHLORIDE;(2E)-3-[1-[[4-[(Dimethylamino)methyl]phenyl]sulfonyl]-1H-pyrrol-3-yl]-N-hydroxy-2-propenamide hydrochloride (1:1)
CBNumber: CB92666678
Molecular Formula: C16H20ClN3O4S
Formula Weight: 385.8657
MOL File: 1187075-34-8.mol

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RAS-2410 hydrochloride Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: crystalline solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 17553
Product name: Resminostat (hydrochloride)
Purity: ≥95%
Packaging: 1mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 17553
Product name: Resminostat (hydrochloride)
Purity: ≥95%
Packaging: 5mg
Price: $190
Updated: 2024/03/01

Cayman Chemical

Product number: 17553
Product name: Resminostat (hydrochloride)
Purity: ≥95%
Packaging: 10mg
Price: $310
Updated: 2024/03/01

Cayman Chemical

Product number: 17553
Product name: Resminostat (hydrochloride)
Purity: ≥95%
Packaging: 50mg
Price: $947
Updated: 2024/03/01

ApexBio Technology

Product number: A3755
Product name: Resminostathydrochloride
Packaging: 50mg
Price: $1010
Updated: 2021/12/16

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RAS-2410 hydrochloride Chemical Properties,Usage,Production

Description

Resminostat is an orally bioavailable inhibitor of histone deacetylase 1 (HDAC1), HDAC3, and HDAC6 (IC₅₀s = 43-72 nM), resulting in hyperacetylation of histone H4 in multiple myeloma cells. It abrogates cell growth and strongly induces apoptosis in multiple myeloma cells (IC₅₀s = 2.5-3 μM). Resminostat displays synergistic effects when combined with melphalan and the proteasome inhibitors bortezomib and S-2209. It dose-dependently inhibits HDAC activity in vivo.

References

[1] mandl-weber s, meinel fg, jankowsky r, oduncu f, schmidmaier r, baumann p. the novel inhibitor of histone deacetylase resminostat (ras2410) inhibits proliferation and induces apoptosis in multiple myeloma (mm) cells. br j haematol. 2010 may;149(4):518-28.
[2] brunetto at, ang je, lal r, olmos d, molife lr, kristeleit r, parker a, casamayor i, olaleye m, mais a, hauns b, strobel v, hentsch b, de bono js. first-in-human, pharmacokinetic and pharmacodynamic phase i study of resminostat, an oral histone deacetylase inhibitor, in patients with advanced solid tumors. clin cancer res. 2013 oct 1;19(19):5494-504.

RAS-2410 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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RAS-2410 hydrochloride Suppliers

China 47 United States 8 Global 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
Advantage: 61

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4863
Advantage: 58

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4121
Advantage: 55

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9254
Advantage: 55

ShangHai Angti Biotechnology Co., Ltd.

Tel: 13764913901
Fax: -
Email: info@angtibio.com
Country: China
ProdList: 4493
Advantage: 55

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3868
Advantage: 58

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8003
Advantage: 62

Shanghai Rechem science Co., Ltd.

Tel: 21-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2982
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131981
Advantage: 58

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View Lastest Price from RAS-2410 hydrochloride manufacturers

Zhejiang J&C Biological Technology Co.,Limited

Product: RAS-2410 hydrochloride 1187075-34-8
Price: US $0.00/gram
Min. Order: 1gram
Purity: 99%
Supply Ability: 10kg
Release date: 2022-02-18

1187075-34-8, RAS-2410 hydrochlorideRelated Search:

4SC-201 hydrochloride

RAS 2410 hydrochloride

RAS2410 hydrochloride

RAS-2410 hydrochloride

ResMinostat (hydrochloride)

(2E)-3-[1-[[4-[(Dimethylamino)methyl]phenyl]sulfonyl]-1H-pyrrol-3-yl]-N-hydroxy-2-propenamide hydrochloride (1:1)

Resminostat HCl

RAS2410; 4SC-201; RAS 2410; RAS-2410;4SC201;4SC 201

Resminostat hydrochloride (4SC-201)

RAS2410 HYDROCHLORIDE; 4SC-201 HYDROCHLORIDE; RAS 2410 HYDROCHLORIDE; RAS-2410 HYDROCHLORIDE

RAS-2410,Resminostat hydrochloride,Resminostat,4SC-201,Histone deacetylases,Inhibitor,RAS 2410,inhibit,RAS2410,HDAC

1187075-34-8

C16H19N3O4SHCl

APIs