RAS-2410 hydrochloride

Product Name: RAS-2410 hydrochloride
CAS No.: 1187075-34-8
Chemical Name: RAS-2410 hydrochloride
Synonyms: RAS-2410 HCl;Resminostat HCl;RAS2410 hydrochloride;4SC-201 hydrochloride;RAS-2410 hydrochloride;RAS 2410 hydrochloride;ResMinostat (hydrochloride);Resminostat hydrochloride (4SC-201);RAS2410; 4SC-201; RAS 2410; RAS-2410;4SC201;4SC 201;RAS2410 HYDROCHLORIDE; 4SC-201 HYDROCHLORIDE; RAS 2410 HYDROCHLORIDE; RAS-2410 HYDROCHLORIDE
CBNumber: CB92666678
Molecular Formula: C16H20ClN3O4S
Formula Weight: 385.8657
MOL File: 1187075-34-8.mol

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RAS-2410 hydrochloride Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: crystalline solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 17553
Product name: Resminostat (hydrochloride)
Purity: ≥95%
Packaging: 1mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 17553
Product name: Resminostat (hydrochloride)
Purity: ≥95%
Packaging: 5mg
Price: $190
Updated: 2024/03/01

Cayman Chemical

Product number: 17553
Product name: Resminostat (hydrochloride)
Purity: ≥95%
Packaging: 10mg
Price: $310
Updated: 2024/03/01

Cayman Chemical

Product number: 17553
Product name: Resminostat (hydrochloride)
Purity: ≥95%
Packaging: 50mg
Price: $947
Updated: 2024/03/01

ApexBio Technology

Product number: A3755
Product name: Resminostathydrochloride
Packaging: 5mg
Price: $173
Updated: 2021/12/16

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RAS-2410 hydrochloride Chemical Properties,Usage,Production

Description

Resminostat is an orally bioavailable inhibitor of histone deacetylase 1 (HDAC1), HDAC3, and HDAC6 (IC₅₀s = 43-72 nM), resulting in hyperacetylation of histone H4 in multiple myeloma cells. It abrogates cell growth and strongly induces apoptosis in multiple myeloma cells (IC₅₀s = 2.5-3 μM). Resminostat displays synergistic effects when combined with melphalan and the proteasome inhibitors bortezomib and S-2209. It dose-dependently inhibits HDAC activity in vivo.

References

[1] mandl-weber s, meinel fg, jankowsky r, oduncu f, schmidmaier r, baumann p. the novel inhibitor of histone deacetylase resminostat (ras2410) inhibits proliferation and induces apoptosis in multiple myeloma (mm) cells. br j haematol. 2010 may;149(4):518-28.
[2] brunetto at, ang je, lal r, olmos d, molife lr, kristeleit r, parker a, casamayor i, olaleye m, mais a, hauns b, strobel v, hentsch b, de bono js. first-in-human, pharmacokinetic and pharmacodynamic phase i study of resminostat, an oral histone deacetylase inhibitor, in patients with advanced solid tumors. clin cancer res. 2013 oct 1;19(19):5494-504.

RAS-2410 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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RAS-2410 hydrochloride Suppliers

China 47 United States 8 Global 55

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38631
Advantage: 58

ApexBio Technology

Tel: --
Fax: --
Email: sales@apexbt.com
Country: United States
ProdList: 6251
Advantage: 58

Cayman Chemical Company

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Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

Creative Enzymes

Tel: --
Fax: --
Email: info@creative-enzymes.com
Country: United States
ProdList: 6057
Advantage: 58

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View Lastest Price from RAS-2410 hydrochloride manufacturers

Zhejiang J&C Biological Technology Co.,Limited

Product: RAS-2410 hydrochloride 1187075-34-8
Price: US $0.00/gram
Min. Order: 1gram
Purity: 99%
Supply Ability: 10kg
Release date: 2022-02-18

1187075-34-8, RAS-2410 hydrochlorideRelated Search:

4SC-201 hydrochloride

RAS 2410 hydrochloride

RAS2410 hydrochloride

RAS-2410 hydrochloride

ResMinostat (hydrochloride)

(2E)-3-[1-[[4-[(Dimethylamino)methyl]phenyl]sulfonyl]-1H-pyrrol-3-yl]-N-hydroxy-2-propenamide hydrochloride (1:1)

Resminostat HCl

RAS2410; 4SC-201; RAS 2410; RAS-2410;4SC201;4SC 201

Resminostat hydrochloride (4SC-201)

RAS2410 HYDROCHLORIDE; 4SC-201 HYDROCHLORIDE; RAS 2410 HYDROCHLORIDE; RAS-2410 HYDROCHLORIDE

RAS-2410,Resminostat hydrochloride,Resminostat,4SC-201,Histone deacetylases,Inhibitor,RAS 2410,inhibit,RAS2410,HDAC

RAS-2410 HCl

1187075-34-8

C16H19N3O4SHCl

APIs