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E 1210 (pharMaceutical)

Product Name
E 1210 (pharMaceutical)
CAS No.
936339-60-5
Chemical Name
E 1210 (pharMaceutical)
Synonyms
E 1210;APX 001A;Manogepix;APX001A Tosylate;E1210 ( APX001A);APX001A (E 1210);APX001 (APX 001A;Manogepix (E1210);APX001A (Manogepix;E1210, 10 mM in DMSO
CBNumber
CB92668117
Molecular Formula
C21H18N4O2
Formula Weight
358.39
MOL File
936339-60-5.mol
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E 1210 (pharMaceutical) Property

Boiling point:
569.4±45.0 °C(Predicted)
Density 
1.263±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 100 mg/mL (279.03 mM)
pka
5.13±0.36(Predicted)
form 
Solid
color 
White to light yellow
InChI
InChI=1S/C21H18N4O2/c22-21-18(4-3-11-24-21)19-13-17(25-27-19)12-15-6-8-16(9-7-15)14-26-20-5-1-2-10-23-20/h1-11,13H,12,14H2,(H2,22,24)
InChIKey
WSEKTEUGRLFBSE-UHFFFAOYSA-N
SMILES
C1(N)=NC=CC=C1C1ON=C(CC2=CC=C(COC3=NC=CC=C3)C=C2)C=1
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Hazard and Precautionary Statements (GHS)

Signal word
Warning
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N-Bromosuccinimide Price

TRC
Product number
P999733
Product name
3-[3-[[4-[(2-Pyridinyloxy)methyl]phenyl]methyl]-5-isoxazolyl]-2-pyridinamine
Packaging
5mg
Price
$165
Updated
2021/12/16
ChemScene
Product number
CS-0007309
Product name
E1210
Purity
99.30%
Packaging
5mg
Price
$165
Updated
2021/12/16
ChemScene
Product number
CS-0007309
Product name
E1210
Purity
99.30%
Packaging
10mg
Price
$300
Updated
2021/12/16
ChemScene
Product number
CS-0007309
Product name
E1210
Purity
99.30%
Packaging
50mg
Price
$1320
Updated
2021/12/16
ChemScene
Product number
CS-0007309
Product name
E1210
Purity
99.30%
Packaging
100mg
Price
$2250
Updated
2021/12/16
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E 1210 (pharMaceutical) Chemical Properties,Usage,Production

Uses

3-[3-[[4-[(2-Pyridinyloxy)methyl]phenyl]methyl]-5-isoxazolyl]-2-pyridinamine is a new broad-spectrum antifungal.

in vivo

Manogepix (2.5 mg/kg, 5 mg/kg and 10 mg/kg; oral administration; twice daily; for 3 days; specific-pathogen-free female ICR mice) treatment reduces the number of viable C. albicans cells in the oral cavity in a dose-dependent manner[2].

Animal Model:Specific-pathogen-free female ICR mice (5 weeks; ~25 g) with C. albicans[2]
Dosage:2.5 mg/kg, 5 mg/kg and 10 mg/kg
Administration:Oral administration; twice daily; for 3 days
Result:Reduced the number of viable C. albicans cells in the oral cavity in a dose-dependent manner.

E 1210 (pharMaceutical) Preparation Products And Raw materials

Raw materials

Preparation Products

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E 1210 (pharMaceutical) Suppliers

China 57 United States 5 Global 62
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
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12952
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TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
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58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
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58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
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58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58

936339-60-5, E 1210 (pharMaceutical)Related Search:

CHOLESTEROL ESTERASE

  • E 1210
  • E 1210 (pharMaceutical)
  • 3-[3-[[4-(pyridin-2-yloxymethyl)phenyl]methyl]-1,2-oxazol-5-yl]pyridin-2-amine
  • APX 001A
  • APX001 (APX 001A
  • 2-Pyridinamine, 3-[3-[[4-[(2-pyridinyloxy)methyl]phenyl]methyl]-5-isoxazolyl]-
  • E1210 ( APX001A)
  • APX001A Tosylate
  • 3-[3-[[4-[(2-Pyridinyloxy)methyl]phenyl]methyl]-5-isoxazolyl]-2-pyridinamine
  • APX001A (E 1210)
  • APX001A (Manogepix
  • E-1210,Gwt1p,broad-spectrum,E1210,Glycosylphosphatidylinositol,inhibit,Fungal,disseminated,Inhibitor
  • Manogepix
  • Manogepix (E1210)
  • 3-(3-(4-((Pyridin-2-yloxy)methyl)benzyl)isoxazol-5-yl)pyridin-2-amine
  • E1210, 10 mM in DMSO
  • Manogepix (E1210) ，S0491
  • 936339-60-5