ChemicalBook > CAS DataBase List > 2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide

2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide

Product Name
2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide
CAS No.
1256493-34-1
Chemical Name
2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide
Synonyms
o-4a;Dyng;Dyngo-49;Dyngo-4a;Hydroxy-Dynasore;3-Hydroxy-N'-(2,4,5-trihydroxybenzylidene)-2-naphthohydrazide;3-Hydroxy-N'-(2,4,5-trihydroxybenzylidene)-2-naphthohydrazide;3-Hydroxy-N′-[(2,4,5-trihydroxyphenyl)methylidene]naphthalene-2-carbohydrazide;3-Hydroxy-2-naphthalenecarboxylic acid 2-[(2,4,5-trihydroxyphenyl)methylene]hydrazide;3-Hydroxynaphthalene-2-carboxylic acid 2-[(2,4,5)-trihydroxyphenyl)methylene]hydrazide
CBNumber
CB92668283
Molecular Formula
C18H14N2O5
Formula Weight
338.31
MOL File
1256493-34-1.mol
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2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide Property

Density 
1.45±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: >10mg/mL
pka
8.28±0.40(Predicted)
form 
powder
color 
faint yellow to dark yellow
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Safety

Hazard Codes 
N
Risk Statements 
50
Safety Statements 
61
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H361Suspected of damaging fertility or the unborn child

H372Causes damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0340
Product name
Hydroxy-Dynasore
Purity
≥98% (HPLC)
Packaging
5mg
Price
$127
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0340
Product name
Hydroxy-Dynasore
Purity
≥98% (HPLC)
Packaging
25mg
Price
$505
Updated
2024/03/01
Cayman Chemical
Product number
29479
Product name
Dyngo-4a
Packaging
10mg
Price
$109
Updated
2024/03/01
Cayman Chemical
Product number
29479
Product name
Dyngo-4a
Packaging
100mg
Price
$714
Updated
2024/03/01
Cayman Chemical
Product number
29479
Product name
Dyngo-4a
Packaging
5mg
Price
$62
Updated
2024/03/01
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2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide Chemical Properties,Usage,Production

Uses

Hydroxy-Dynasore is an inhibitor of dynamin I and dynamin II.

Definition

ChEBI: Dyngo-4a is dynamin inhibitor. It has a role as an EC 3.6.5.5 (dynamin GTPase) inhibitor.

Biochem/physiol Actions

Hydroxy-Dynasore is a cell permeable and potent dynamin inhibitor that prevents uptake of recombinant botulinum neurotoxin A heavy chain binding domain (BoNT/A-Hc). Apparently, Hydroxy-Dynasore prevents dynamin-mediated fission of endocytic vesicles from the plasma membrane.

storage

Store at -20°C

2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide Suppliers

ShangHai Caerulum Pharma Discovery Co., Ltd.
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China
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Finetech Industry Limited
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Sigma-Aldrich
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SPIRO PHARMA
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Shanghai Chaolan Chemical Technology Center
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View Lastest Price from 2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide manufacturers

Career Henan Chemical Co
Product
2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide 1256493-34-1
Price
US $1.00/g
Min. Order
1g
Purity
99.99%
Supply Ability
200kg
Release date
2019-12-24

1256493-34-1, 2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazideRelated Search:


  • 2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide
  • Dyngo-49
  • 3-Hydroxy-2-naphthalenecarboxylic acid 2-[(2,4,5-trihydroxyphenyl)methylene]hydrazide
  • 3-Hydroxy-N′-[(2,4,5-trihydroxyphenyl)methylidene]naphthalene-2-carbohydrazide
  • Hydroxy-Dynasore
  • Dyngo-4a
  • 3-Hydroxynaphthalene-2-carboxylic acid 2-[(2,4,5)-trihydroxyphenyl)methylene]hydrazide
  • Dyng
  • o-4a
  • 3-Hydroxy-N'-(2,4,5-trihydroxybenzylidene)-2-naphthohydrazide
  • inhibit,Hydroxy-Dynasore,vesicle,Dynamin,Hydroxy Dynasore,Neuron,clathrin‐coated,Inhibitor,Endocytosis,Dynamin,GTPase,HydroxyDynasore
  • 3-Hydroxy-N'-(2,4,5-trihydroxybenzylidene)-2-naphthohydrazide
  • 1256493-34-1