ChemicalBook > CAS DataBase List > Necrostatin-7 (Nec-7)
Necrostatin-7 (Nec-7)
- Product Name
- Necrostatin-7 (Nec-7)
- CAS No.
- 351062-08-3
- Chemical Name
- Necrostatin-7 (Nec-7)
- Synonyms
- Nec-7;Necrostatin-7;Necrostatin-7 (Nec-7);Necrostatin-7 >=98% (HPLC), powder;Necrostatin-7, Necroptosis inhibitor;5-[[3-(4-Fluorophenyl)-1H-pyrazol-4-yl]methylene]-2-imino-3-(2-thiazolyl)-4-thiazolidinone;5-((3-(4-Fluorophenyl)-1H-pyrazol-4-yl)methylene)-2-imino-3-(thiazol-2-yl)thiazolidin-4-one;4-Thiazolidinone, 5-[[3-(4-fluorophenyl)-1H-pyrazol-4-yl]methylene]-2-imino-3-(2-thiazolyl)-;(5Z)-5-[[5-(4-fluorophenyl)-1H-pyrazol-4-yl]methylidene]-2-imino-3-(1,3-thiazol-2-yl)-1,3-thiazolidin-4-one
- CBNumber
- CB92677870
- Molecular Formula
- C16H10FN5OS2
- Formula Weight
- 371.41
- MOL File
- 351062-08-3.mol
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Necrostatin-7 (Nec-7) Property
- Boiling point:
- 613.4±65.0 °C(Predicted)
- Density
- 1.63±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: >10mg/mL (with warming)
- pka
- 11.56±0.50(Predicted)
- form
- powder
- color
- yellow to tan
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 10528
- Product name
- Necrostatin-7
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $106
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 10528
- Product name
- Necrostatin-7
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $363
- Updated
- 2024/03/01
Usbiological
- Product number
- 045075
- Product name
- Necrostatin-7
- Packaging
- 5mg
- Price
- $316
- Updated
- 2021/12/16
Usbiological
- Product number
- N2059-27
- Product name
- Necrostatin-7
- Packaging
- 5mg
- Price
- $356
- Updated
- 2021/12/16
AK Scientific
- Product number
- 6241CE
- Product name
- Necrostatin-7
- Packaging
- 5mg
- Price
- $214
- Updated
- 2021/12/16
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Necrostatin-7 (Nec-7) Chemical Properties,Usage,Production
Biological Activity
Necrostatin-7 (Nec-7) is a potent inhibitor of necroptosis, a regulated caspase-independent necrotic cell death pathway, distinct from apoptosis. Nec-7 has a different profile from the other necrostatins as it does not inhibit RIP1 kinase, suggesting the possibility th at it may target an additional as yet unknown regulatory molecule in the pathway.
storage
+4°C
Necrostatin-7 (Nec-7) Preparation Products And Raw materials
Raw materials
Preparation Products
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Necrostatin-7 (Nec-7) Suppliers
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