ChemicalBook > CAS DataBase List > (2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone, 3',5,7-Trihydroxy-4-methoxyflavanone

(2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone, 3',5,7-Trihydroxy-4-methoxyflavanone

Product Name
(2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone, 3',5,7-Trihydroxy-4-methoxyflavanone
CAS No.
69097-99-0
Chemical Name
(2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone, 3',5,7-Trihydroxy-4-methoxyflavanone
Synonyms
rac-Hesperetin;(±)-Hesperetin;Hesperetin, 97%+;(R,S)-hesperetin;(+/-)-Hesperetin;13C-rac-Hesperetin;Amiloride Impurity 8;rac-Hesperetin-13C-d3;rac- Diossmin EP Impurity G;Rac-Hesperetin (Diosmin Impurity G)
CBNumber
CB92699300
Molecular Formula
C16H14O6
Formula Weight
302.28
MOL File
69097-99-0.mol
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(2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone, 3',5,7-Trihydroxy-4-methoxyflavanone Property

Melting point:
227-232°C
Boiling point:
586.2±50.0 °C(Predicted)
Density 
1.458±0.06 g/cm3(Predicted)
FEMA 
4313 | 5,7-DIHYDROXY-2-(3-HYDROXY-4-METHOXYPHENYL)CHROMAN-4-ONE
storage temp. 
2-8°C
solubility 
ethanol: soluble50mg/mL, clear to almost clear, colorless to slightly yellow
form 
powder (with a light tan cast)
pka
7.49±0.40(Predicted)
color 
Pale Yellow to Light Brown
biological source
synthetic
JECFA Number
2024
LogP
1.938 (est)
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Safety

WGK Germany 
2
HS Code 
2932990090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H4125
Product name
Hesperetin
Purity
analytical standard
Packaging
1g
Price
$37.1
Updated
2025/07/31
Sigma-Aldrich
Product number
W431300
Product name
Hesperetin
Purity
≥95%
Packaging
5g
Price
$86.4
Updated
2025/07/31
Sigma-Aldrich
Product number
W431300
Product name
Hesperetin
Purity
≥95%
Packaging
50g
Price
$377
Updated
2025/07/31
Sigma-Aldrich
Product number
H4125
Product name
Hesperetin
Purity
analytical standard
Packaging
10g
Price
$173.85
Updated
2025/07/31
TRC
Product number
H289501
Product name
rac-Hesperetin
Packaging
1g
Price
$120
Updated
2021/12/16
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(2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone, 3',5,7-Trihydroxy-4-methoxyflavanone Chemical Properties,Usage,Production

Uses

Hesperetin has been used as a standard in studies involving the cytotoxic effect of hesperetin on doxorubicin-resistant MCF-7 cells using enzyme-linked immunosorbent assay (ELISA) technique.

Definition

ChEBI: 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one is an ether and a member of flavonoids.

General Description

Hesperetin is an aglycon form of flavonoid, which can be found in peels of citrus fruits.

Biochem/physiol Actions

Dietary flavanone with chemopreventive effect.

(2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone, 3',5,7-Trihydroxy-4-methoxyflavanone Preparation Products And Raw materials

Raw materials

Preparation Products

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(2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone, 3',5,7-Trihydroxy-4-methoxyflavanone Suppliers

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69097-99-0, (2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone, 3',5,7-Trihydroxy-4-methoxyflavanoneRelated Search:

3-HYDROXYFLAVONE 5-HYDROXYFLAVONE 3,3',4',5,6,7,8-heptamethoxyflavone 7-HYDROXYFLAVONE

  • (2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone, 3',5,7-Trihydroxy-4-methoxyflavanone
  • 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone
  • rac-Hesperetin
  • 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one
  • Diosmin Impurity 7 (Diosmin EP Impurity G) (rac-Hesperetin)
  • Rac-Hesperetin (Diosmin Impurity G)
  • rac-Hesperetin (rac-Diosmin EP Impurity G)
  • 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-
  • (+/-)-Hesperetin
  • (R,S)-hesperetin
  • Hesperetin, 97%+
  • rac-Hesperetin-13C-d3
  • Amiloride Impurity 8
  • rac-Hesperetin-13C-d3 (rac-Diosmin EP Impurity G-13C-d3)
  • rac- Diossmin EP Impurity G
  • (±)-Hesperetin
  • 13C-rac-Hesperetin
  • 69097-99-0