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Diphenylvinylsulfonium Triflate

Product Name
Diphenylvinylsulfonium Triflate
CAS No.
247129-88-0
Chemical Name
Diphenylvinylsulfonium Triflate
Synonyms
Diphenyl(vinyl)sulfonium trifluoromethanesulfonate;Diphenylvinylsulfonium triflate;ethenyl(diphenyl)sulfanium;Sulfonium hanesulfonate (1:1);ethenyldiphenylsulfanium trifluoromethanesulfonate;SulfoniuM, ethenyldiphenyl-, 1,1,1-trifluoroMethanesulfonate;SulfoniuM, ethenyldiphenyl-, 1,1,1-trifluoroMethanesulfonate (1:1)
CBNumber
CB92704802
Molecular Formula
C15H13F3O3S2
Formula Weight
362.38
MOL File
247129-88-0.mol
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Diphenylvinylsulfonium Triflate Property

storage temp. 
Sealed in dry,Room Temperature
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FD146166
Product name
Diphenylvinylsulfonium triflate
Packaging
25mg
Price
$50
Updated
2021/12/16
Synthonix
Product number
D6369
Product name
DiphenylvinylsulfoniumTriflate
Purity
97.0%
Packaging
1g
Price
$80
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD146166
Product name
Diphenylvinylsulfonium triflate
Packaging
50mg
Price
$80
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD146166
Product name
Diphenylvinylsulfonium triflate
Packaging
100mg
Price
$125
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD146166
Product name
Diphenylvinylsulfonium triflate
Packaging
500mg
Price
$300
Updated
2021/12/16
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Diphenylvinylsulfonium Triflate Chemical Properties,Usage,Production

Description

Diphenylvinylsulfonium Triflate is a pale yellow, oily organic compound. It has a vinylsulfonium salt structure, and nucleophiles readily undergo conjugate addition reactions with vinylsulfonium salts to form thionimide intermediates, which can undergo a series of further transformations. Applications in epoxidation, azide and other cyclisation reactions have demonstrated the broad applicability of vinyl sulfonium salts as two-carbon bridges.

Uses

Diphenylvinylsulfonium Triflate can be used as GLP-??1r modulating compounds to treat GLP-??1R mediated diseases such as metabolic and related diseases, including but not limited to NASH, obesity, and type 2 diabetes.

Synthesis

Diphenylvinylsulfonium Triflate is synthesised using (2-bromoethyl)diphenylsulfonium trifluoromethanesulfonate as a raw material by chemical reaction. The specific synthesis steps are as follows:
INTERMEDIATE 75(DiphenylXvmyDsulfonium trifluoromethanesulfonateIntermediate 74 (11.4 g, 25.7 mmol) was dissolved in THF/H2O (2:1) (42 mL). KHCO3 (3.1 g, 30.9 mmol) was added and the reaction mixture was stirred for 20 minutes at r.t. The solvent was evaporated immediately under reduced pressure (using a rotary evaporator connected to a high vacuum pump and keeping the water-bath temperature below 2O0C). The reaction mixture was then redissolved in DCM (40 mL), dried over MgSO4, filtered and evaporated. The residue was redissolved in DCM (10 mL) and loaded onto a silica bed (4 cm depth and 2.5 cm diameter). The resulting band was covered with 1 cm sand and eluted with DCM (400 mL), followed by 10% MeOH in DCM (200 mL). The product was isolated as a light brown oil (9.53 g, quantitative). 6H (CDCl3) 7.90-7.87 (4H, m), 7.79-7.66 (6H, m), 7.53 (IH, dd, J 8.8, 8.8 Hz), 6.69 (IH, dd, J 9.5, 2.5 Hz), 6.55 (IH, dd, J 16.5, 2.5 Hz).

Diphenylvinylsulfonium Triflate Preparation Products And Raw materials

Raw materials

Preparation Products

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Diphenylvinylsulfonium Triflate Suppliers

Shanghai Champ Biopharmaceuticals Co., Ltd.
Tel
021-61537865 13585780846
Email
sales@champchem.com
Country
China
ProdList
360
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58
Nanjing Zhiyan Pharmaceutical Technology Co. Ltd.
Tel
18602559219
Email
sales@zhiyanchem.com
Country
China
ProdList
109
Advantage
58
Nanjing dekerui pharmaceutical chemical co., LTD
Tel
025-025-57059602 13913847787
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025-57059601
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26639969@qq.com
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China
ProdList
291
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Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
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sales8178@energy-chemical.com
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China
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Tetranov Biopharm
Tel
13526569071
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sales@leadmedpharm.com
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China
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Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
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China
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Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
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info@topbiochem.com
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China
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Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
18017383231 18017383231
Fax
qq:2817624287
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lyh_antaeus@163.com
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China
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Struchem Co., Ltd.
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0512-0512-63009836 15365350169
Fax
0512-63006936
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helen@struchem.com
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China
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SPIRO PHARMA
Tel
Fax
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Email
eric_feng1954@126.com
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247129-88-0, Diphenylvinylsulfonium TriflateRelated Search:


  • SulfoniuM, ethenyldiphenyl-, 1,1,1-trifluoroMethanesulfonate (1:1)
  • ethenyldiphenylsulfanium trifluoromethanesulfonate
  • Diphenyl(vinyl)sulfonium trifluoromethanesulfonate
  • Diphenylvinylsulfonium triflate
  • SulfoniuM, ethenyldiphenyl-, 1,1,1-trifluoroMethanesulfonate
  • ethenyl(diphenyl)sulfanium
  • Sulfonium hanesulfonate (1:1)
  • 247129-88-0
  • 247125-88-0
  • C15H13F3O3S2
  • C14H13SCF3O3S