ChemicalBook > CAS DataBase List > (R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanoic acid

(R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanoic acid

Product Name
(R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanoic acid
CAS No.
1608986-16-8
Chemical Name
(R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanoic acid
Synonyms
Bortezomib (2R)-Acid;Bortezomib Acid R-Isomer;(pyrazine-2-carbonyl)-D-phenylalanine;D-Phenylalanine, N-(2-pyrazinylcarbonyl)-;(R)-3-Phenyl-2-(pyrazine-2-carboxamido)propanoic acid;(2R)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoic acid;(R)-3-Phenyl-2-(pyrazine-2-carboxamido)propanoic acid? (Bortezomib Impurity)
CBNumber
CB92705304
Molecular Formula
C14H13N3O3
Formula Weight
271.27
MOL File
1608986-16-8.mol
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(R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanoic acid Property

Boiling point:
573.8±50.0 °C(Predicted)
Density 
1.323±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
Powder
pka
13.93±0.46(Predicted)
color 
Yellowish
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
P841505
Product name
N-(2-Pyrazinylcarbonyl)-D-phenylalanine
Packaging
250mg
Price
$670
Updated
2021/12/16
SynQuest Laboratories
Product number
4H58-1-9E
Product name
(R)-3-Phenyl-2-(pyrazine-2-carboxamido)propanoic acid
Packaging
1g
Price
$791
Updated
2021/12/16
AK Scientific
Product number
4956DD
Product name
(R)-3-Phenyl-2-(pyrazine-2-carboxamido)propanoicacid
Packaging
1g
Price
$810
Updated
2021/12/16
AK Scientific
Product number
4956DD
Product name
(R)-3-Phenyl-2-(pyrazine-2-carboxamido)propanoicacid
Packaging
100mg
Price
$258
Updated
2021/12/16
AK Scientific
Product number
4956DD
Product name
(R)-3-Phenyl-2-(pyrazine-2-carboxamido)propanoicacid
Packaging
250mg
Price
$342
Updated
2021/12/16
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(R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanoic acid Chemical Properties,Usage,Production

Uses

N-(2-Pyrazinylcarbonyl)-D-phenylalanine is an starting intermediate in the synthesis of Bortezomib (B675700) from L-phenylalanine via dipeptidyl boronic acid ester intermediates.

(R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanoic acid Suppliers

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1608986-16-8, (R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanoic acidRelated Search:

Isovaleraldehyde Bortezomib Impurity 8 4,6-Methano-1,3,2-benzodioxaborole,2-[(1S)-1-chloro-3-Methylbutyl]hexahydro-3a,5,5-triMethyl-,(3aS,4S,6S,7aR)- Bortezomib Impurity 57 (1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate BORTEZOMIB-PINANEDIOL Bortezomib intermediates II 3,6-Dibenzylhexahydropyrazine-2,5-dione Bortezomib Impurity 52 Bortezomib Impurity 9 Desisobutyl-n-butyl BortezoMib (IS,2S,3R,5S)-Pinanediol-L-phenylalanine-L-leucine boronate, HCl salt (S,E)-N-(1-((3-methylbut-1-en-1-yl)amino)-1-oxo-3-phenylpropan-2-yl) pyrazine-2-carboxamide Bortezomib Impurity 32 (S)-(+)-PINANEDIOL (DICHLORMETHYL)BORONATE Bortezomib Impurity 47 HCl Bortezomib Impurity 60 4,6-Methano-1,3,2-benzodioxaborole-2-methanamine

  • Bortezomib (2R)-Acid
  • Bortezomib Acid R-Isomer
  • D-Phenylalanine, N-(2-pyrazinylcarbonyl)-
  • (R)-3-Phenyl-2-(pyrazine-2-carboxamido)propanoic acid? (Bortezomib Impurity)
  • (pyrazine-2-carbonyl)-D-phenylalanine
  • (R)-3-Phenyl-2-(pyrazine-2-carboxamido)propanoic acid
  • (2R)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoic acid
  • 1608986-16-8