GSK-LSD1
- Product Name
- GSK-LSD1
- CAS No.
- 1431368-48-7
- Chemical Name
- GSK-LSD1
- Synonyms
- GSK-LSD1 2HCl;CS-1628;GSK-LSD;GSK-LSD1;GSK-LSD1 HC'k;GSKLSD1 GSK LSD1;GSK-LSD1(LSD1inhibitor);GSK-LSD1 2hydrochloride;GSK-LSD1 2HCl USP/EP/BP;GSK-LSD1 (trans-racemic)
- CBNumber
- CB92738768
- Molecular Formula
- C14H20N2
- Formula Weight
- 216.32
- MOL File
- 1431368-48-7.mol
GSK-LSD1 Property
- Boiling point:
- 347.4±42.0 °C(Predicted)
- Density
- 1.07±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- H2O: soluble20mg/mL, clear
- form
- powder
- pka
- 10.14±0.10(Predicted)
- color
- white to beige
- Water Solubility
- H2O: 20mg/mL, clear
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- SML1072
- Product name
- GSK-LSD1
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $118
- Updated
- 2025/07/31
- Product number
- SML1072
- Product name
- GSK-LSD1
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $475
- Updated
- 2025/07/31
- Product number
- 5361
- Product name
- GSKLSD1dihydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $181
- Updated
- 2021/12/16
- Product number
- G797570
- Product name
- GSKLSD1Dihydrochloride
- Packaging
- 5mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- G797570
- Product name
- GSKLSD1Dihydrochloride
- Packaging
- 10mg
- Price
- $125
- Updated
- 2021/12/16
GSK-LSD1 Chemical Properties,Usage,Production
Uses
GSK LSD1 Dihydrochloride is an irreversible mechanism-based inhibitor of LSD1. Lysine-specific demthylase 1 (LSD1) belonges to the flavin adenine dinucleotide (FAD) family-dependant amine oxidases that include MAOs and PAOs. Inhibits cell proliferation in cancer cell lines.
Uses
GSK-LSD1 has been used as a lysine specific demethylase 1 (LSD1) inhibitor in mice to study sepsis-induced mortality. It has also been used as an inhibitor to study if the effect of phenelzine activation of human immunodeficiency virus (HIV) latency is caused due to LSD1.
Biochem/physiol Actions
GSK-LSD1 is a potent and selective inhibitor of lysine specific demethylase 1 (LSD1). GSK-LSD1 potently inhibits proliferation of varies cancer cell lines by changing gene expression patterns. For full characterization details, please visit the GSK-LSD1 probe summary on the Structural Genomics Consortium (SGC) website.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
References
[1]. structural genomics consortium.http://www. thesgc.org/chemical-probes/lsd1.
GSK-LSD1 Preparation Products And Raw materials
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