ChemicalBook > CAS DataBase List > GSK-LSD1

GSK-LSD1

Product Name
GSK-LSD1
CAS No.
1431368-48-7
Chemical Name
GSK-LSD1
Synonyms
GSK-LSD1 2HCl;CS-1628;GSK-LSD;GSK-LSD1;GSK-LSD1 HC'k;GSKLSD1 GSK LSD1;GSK-LSD1(LSD1inhibitor);GSK-LSD1 2hydrochloride;GSK-LSD1 2HCl USP/EP/BP;GSK-LSD1 (trans-racemic)
CBNumber
CB92738768
Molecular Formula
C14H20N2
Formula Weight
216.32
MOL File
1431368-48-7.mol
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GSK-LSD1 Property

Boiling point:
347.4±42.0 °C(Predicted)
Density 
1.07±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
H2O: soluble20mg/mL, clear
form 
powder
pka
10.14±0.10(Predicted)
color 
white to beige
Water Solubility 
H2O: 20mg/mL, clear
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1072
Product name
GSK-LSD1
Purity
≥98% (HPLC)
Packaging
5mg
Price
$118
Updated
2025/07/31
Sigma-Aldrich
Product number
SML1072
Product name
GSK-LSD1
Purity
≥98% (HPLC)
Packaging
25mg
Price
$475
Updated
2025/07/31
Tocris
Product number
5361
Product name
GSKLSD1dihydrochloride
Purity
≥98%(HPLC)
Packaging
10
Price
$181
Updated
2021/12/16
TRC
Product number
G797570
Product name
GSKLSD1Dihydrochloride
Packaging
5mg
Price
$70
Updated
2021/12/16
TRC
Product number
G797570
Product name
GSKLSD1Dihydrochloride
Packaging
10mg
Price
$125
Updated
2021/12/16
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GSK-LSD1 Chemical Properties,Usage,Production

Uses

GSK LSD1 Dihydrochloride is an irreversible mechanism-based inhibitor of LSD1. Lysine-specific demthylase 1 (LSD1) belonges to the flavin adenine dinucleotide (FAD) family-dependant amine oxidases that include MAOs and PAOs. Inhibits cell proliferation in cancer cell lines.

Uses

GSK-LSD1 has been used as a lysine specific demethylase 1 (LSD1) inhibitor in mice to study sepsis-induced mortality. It has also been used as an inhibitor to study if the effect of phenelzine activation of human immunodeficiency virus (HIV) latency is caused due to LSD1.

Biochem/physiol Actions

GSK-LSD1 is a potent and selective inhibitor of lysine specific demethylase 1 (LSD1). GSK-LSD1 potently inhibits proliferation of varies cancer cell lines by changing gene expression patterns. For full characterization details, please visit the GSK-LSD1 probe summary on the Structural Genomics Consortium (SGC) website.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc

References

[1]. structural genomics consortium.http://www. thesgc.org/chemical-probes/lsd1.

GSK-LSD1 Preparation Products And Raw materials

Raw materials

Preparation Products

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1431368-48-7, GSK-LSD1Related Search:


  • GSK-LSD1 2HCl
  • GSKLSD1 GSK LSD1
  • GSK-LSD1 (trans-racemic)
  • N-[(1R,2S)-2-phenylcyclopropyl]piperidin-4-amine
  • CS-1628
  • GSK-LSD1 HC'k
  • rel-N-[(1R,2S)-2-Phenylcyclopropyl]-4-piperidinamine
  • GSK-LSD1 2hydrochloride
  • GSK-LSD1 dihydrochloride
  • GSK-LSD1 dihydrochloride(GSK-LSD1 2HCl)
  • GSK-LSD1(LSD1inhibitor)
  • N-((1R,2S)-2-phenylcyclopropyl)piperidin-4-amine dihydrochloride
  • GSK-LSD1 (trans-racemic) dihydrochloride
  • rel- N-[(1R,2S)-2-Phenylcyclopropyl]-4-Piperidinamine hydrochloride (1:2)
  • GSK-LSD
  • 4-Piperidinamine, N-[(1R,2S)-2-phenylcyclopropyl]-, rel-
  • GSK-LSD1 2HCl USP/EP/BP
  • GSK-LSD1
  • 1431368-48-7
  • Inhibitors