10-[(4-Methylphenyl)sulfonyl]-10H-phenoxazine

Product Name: 10-[(4-Methylphenyl)sulfonyl]-10H-phenoxazine
CAS No.: 55476-47-6
Chemical Name: 10-[(4-Methylphenyl)sulfonyl]-10H-phenoxazine
Synonyms: PSB-12062;PSB-12062 >=98% (HPLC);10-Tosyl-10H-phenoxazine;N-(p-Methylphenylsulfonyl)phenoxazine;10-[(4-Methylphenyl)sulfonyl]-10H-phenoxazine;10H-Phenoxazine, 10-[(4-methylphenyl)sulfonyl]-;P2X Receptor,Inhibitor,PSB12062,PSB 12062,PSB-12062,P2XRs,inhibit
CBNumber: CB92751073
Molecular Formula: C19H15NO3S
Formula Weight: 337.39
MOL File: 55476-47-6.mol

More

Less

10-[(4-Methylphenyl)sulfonyl]-10H-phenoxazine Property

storage temp.: 2-8°C
solubility: DMSO: soluble2mg/mL, clear (warmed)
form: powder
color: white to beige

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P273Avoid release to the environment.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0753
Product name: PSB-12062
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $119
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0753
Product name: PSB-12062
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $375
Updated: 2024/03/01

ChemScene

Product number: CS-6918
Product name: PSB-12062
Purity: 99.06%
Packaging: 5mg
Price: $60
Updated: 2021/12/16

ChemScene

Product number: CS-6918
Product name: PSB-12062
Purity: 99.06%
Packaging: 10mg
Price: $90
Updated: 2021/12/16

ChemScene

Product number: CS-6918
Product name: PSB-12062
Purity: 99.06%
Packaging: 25mg
Price: $198
Updated: 2021/12/16

More

Less

10-[(4-Methylphenyl)sulfonyl]-10H-phenoxazine Chemical Properties,Usage,Production

Biological Activity

PSB-12062 is a potent and selective P2X4 antagonist with IC50 value of 1.38 μM for human P2X4.

in vitro

10-Tosyl-10H-phenoxazine shows similar potency in human, rat, and mouse species.It shows to be allosteric in nature with a 35-fold selectivity toward P2X4 versus P2X1, P2X2, P2X3, and P2X7. However,it is unable to completely block ATP-induced P2X4-mediated calcium influx even when used at high concentrations (>30 μM).

target

IC50: 1.38 μM (human P2X4), 92.8 nM (rat P2X4), 1.76 μM (mouse P2X4)

10-[(4-Methylphenyl)sulfonyl]-10H-phenoxazine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

10-[(4-Methylphenyl)sulfonyl]-10H-phenoxazine Suppliers

China 32 United States 5 Global 37

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4512
Advantage: 55

Zhengzhou Guancheng Laboratory equipment Sales

Tel: 0371-88888888 272369594
Fax: QQ:272369594
Email: 2723695949@qq.com
Country: China
ProdList: 4891
Advantage: 50

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Shanghai Rechem science Co., Ltd.

Tel: 21-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2991
Advantage: 58

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 7269
Advantage: 58

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400-6387771-6038 18902104717
Email: sales@heowns.com
Country: China
ProdList: 21090
Advantage: 60

Shanghai Yu Ben Biotechnology Co., Ltd.

Tel: 15502154572
Fax: -
Email: yuben012@sina.com
Country: China
ProdList: 508
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

Amel Pharmatech Corporation

Tel: 888-4366503
Fax: 888-502-1736
Email: sales@amelpharmatech.com
Country: China
ProdList: 4266
Advantage: 58

55476-47-6, 10-[(4-Methylphenyl)sulfonyl]-10H-phenoxazineRelated Search:

3-Phenylpyruvic acid Sarcosine (Methoxymethyl)triphenylphosphonium chloride Chlorophenyl

10-[(4-Methylphenyl)sulfonyl]-10H-phenoxazine

PSB-12062

10-Tosyl-10H-phenoxazine

N-(p-Methylphenylsulfonyl)phenoxazine

10H-Phenoxazine, 10-[(4-methylphenyl)sulfonyl]-

PSB-12062 >=98% (HPLC)

P2X Receptor,Inhibitor,PSB12062,PSB 12062,PSB-12062,P2XRs,inhibit

55476-47-6