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10-[(4-Methylphenyl)sulfonyl]-10H-phenoxazine

Product Name
10-[(4-Methylphenyl)sulfonyl]-10H-phenoxazine
CAS No.
55476-47-6
Chemical Name
10-[(4-Methylphenyl)sulfonyl]-10H-phenoxazine
Synonyms
PSB-12062;PSB-12062 >=98% (HPLC);10-Tosyl-10H-phenoxazine;N-(p-Methylphenylsulfonyl)phenoxazine;10-[(4-Methylphenyl)sulfonyl]-10H-phenoxazine;10H-Phenoxazine, 10-[(4-methylphenyl)sulfonyl]-;P2X Receptor,Inhibitor,PSB12062,PSB 12062,PSB-12062,P2XRs,inhibit
CBNumber
CB92751073
Molecular Formula
C19H15NO3S
Formula Weight
337.39
MOL File
55476-47-6.mol
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10-[(4-Methylphenyl)sulfonyl]-10H-phenoxazine Property

storage temp. 
2-8°C
solubility 
DMSO: soluble2mg/mL, clear (warmed)
form 
powder
color 
white to beige
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Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0753
Product name
PSB-12062
Purity
≥98% (HPLC)
Packaging
5mg
Price
$119
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0753
Product name
PSB-12062
Purity
≥98% (HPLC)
Packaging
25mg
Price
$375
Updated
2024/03/01
AK Scientific
Product number
SYN5424
Product name
PSB-12062
Packaging
50mg
Price
$406
Updated
2021/12/16
ChemScene
Product number
CS-6918
Product name
PSB-12062
Purity
99.06%
Packaging
25mg
Price
$198
Updated
2021/12/16
ChemScene
Product number
CS-6918
Product name
PSB-12062
Purity
99.06%
Packaging
5mg
Price
$60
Updated
2021/12/16
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10-[(4-Methylphenyl)sulfonyl]-10H-phenoxazine Chemical Properties,Usage,Production

Biological Activity

PSB-12062 is a potent and selective P2X4 antagonist with IC50 value of 1.38 μM for human P2X4.

in vitro

10-Tosyl-10H-phenoxazine shows similar potency in human, rat, and mouse species.It shows to be allosteric in nature with a 35-fold selectivity toward P2X4 versus P2X1, P2X2, P2X3, and P2X7. However,it is unable to completely block ATP-induced P2X4-mediated calcium influx even when used at high concentrations (>30 μM).

target

IC50: 1.38 μM (human P2X4), 92.8 nM (rat P2X4), 1.76 μM (mouse P2X4)

10-[(4-Methylphenyl)sulfonyl]-10H-phenoxazine Preparation Products And Raw materials

Raw materials

Preparation Products

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10-[(4-Methylphenyl)sulfonyl]-10H-phenoxazine Suppliers

China 28 United States 4 Global 32
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58

55476-47-6, 10-[(4-Methylphenyl)sulfonyl]-10H-phenoxazineRelated Search:

3-Phenylpyruvic acid Sarcosine (Methoxymethyl)triphenylphosphonium chloride Chlorophenyl

  • 10-[(4-Methylphenyl)sulfonyl]-10H-phenoxazine
  • PSB-12062
  • 10-Tosyl-10H-phenoxazine
  • N-(p-Methylphenylsulfonyl)phenoxazine
  • 10H-Phenoxazine, 10-[(4-methylphenyl)sulfonyl]-
  • PSB-12062 >=98% (HPLC)
  • P2X Receptor,Inhibitor,PSB12062,PSB 12062,PSB-12062,P2XRs,inhibit
  • 55476-47-6