3,4-DIMETHOXYPHENYLBORONIC ACID, PINACOL ESTER
- Product Name
- 3,4-DIMETHOXYPHENYLBORONIC ACID, PINACOL ESTER
- CAS No.
- 365564-10-9
- Chemical Name
- 3,4-DIMETHOXYPHENYLBORONIC ACID, PINACOL ESTER
- Synonyms
- 4-DiMethoxyloxyphenyl)-4;2-(3,4-Dimethoxyphenyl)-4,4,5,5-tetramethyl-;3,4-DIMETHOXYPHENYLBORONIC ACID, PINACOL ESTER;3,4-Dimethoxybenzeneboronic acid, pinacol ester;3,4-Dimethoxybenzeneboronic acid, pinacol ester 97%;3,4-DIMETHOXYPHENYLBORONIC ACID, PINACOL ESTER-YL) METHANAMINE;2-(3,4-DIMETHOXYPHENYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE;1,3,2-Dioxaborolane, 2-(3,4-dimethoxyphenyl)-4,4,5,5-tetramethyl-;2-(3,4-DIMETHOXYLOXYPHENYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE;1,2-Dimethoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene
- CBNumber
- CB9279186
- Molecular Formula
- C14H21BO4
- Formula Weight
- 264.13
- MOL File
- 365564-10-9.mol
3,4-DIMETHOXYPHENYLBORONIC ACID, PINACOL ESTER Property
- Melting point:
- 86-87°C
- Boiling point:
- 352.5±32.0 °C(Predicted)
- Density
- 1.05±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- powder to crystal
- color
- White to Almost white
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-36/37/38-36
- Safety Statements
- 36/37/39-26
- WGK Germany
- 3
- HS Code
- 2931900090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BML00086
- Product name
- 3,4-Dimethoxyphenylboronic acid, pinacol ester
- Purity
- AldrichCPR
- Packaging
- 1g
- Price
- $73.1
- Updated
- 2025/07/31
- Product number
- D5533
- Product name
- 2-(3,4-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $35
- Updated
- 2025/07/31
- Product number
- D5533
- Product name
- 2-(3,4-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $102
- Updated
- 2025/07/31
- Product number
- D479228
- Product name
- 3,4-Dimethoxyphenylboronic acid, pinacol ester
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 39917
- Product name
- 2-(3,4-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane,≥98%(GC)
- Purity
- ≥98%(GC)
- Packaging
- 1G
- Price
- $40.77
- Updated
- 2021/12/16
3,4-DIMETHOXYPHENYLBORONIC ACID, PINACOL ESTER Chemical Properties,Usage,Production
Synthesis
91-16-7
73183-34-3
365564-10-9
The reaction of 1,2-dimethoxybenzene (69.9 mg, 0.506 mmol, 1.0 eq.) and bis(pinacolato)diboron (124 mg, 0.486 mmol, 0.96 eq.) was catalyzed by 2,2'-bipyridine (1.7 mg, 11 μmol, 2.2 mol%) and [IrCl(cod)]2 (2.3 mg, 3.4 μmol , 0.68 mol%) were catalyzed by a stirring reaction in heptane (2.5 mL) at 95 °C for 24 hours. After completion of the reaction, the reaction was cooled to room temperature and the reaction mixture was concentrated under reduced pressure and used directly in the next step of the reaction. Subsequently, S-(4-tolyl)-4-toluene thiosulfonate (2a) (69.1 mg, 0.248 mmol, 1.0 equiv), copper sulfate (2.0 mg, 13 μmol, 5.0 mol%), cesium fluoride (80.6 mg, 0.530 mmol, 2.1 equiv), and TMEDA (1.9 mg, 0.16 μmol, 6.6 mol%) were added to the above crude product, dissolved in methanol (2.5 mL) and stirred at 50 °C for 24 hours. After completion of the reaction, it was cooled to room temperature, filtered through a diatomaceous earth pad and the filtrate was concentrated under reduced pressure. The residue was dissolved with ethyl acetate (20 mL), washed sequentially with saturated aqueous sodium bicarbonate (20 mL x 2) and brine (20 mL), and dried over anhydrous sodium sulfate. After filtration, the filtrate was concentrated under reduced pressure and purified by preparative TLC (n-hexane/ethyl acetate=10/1) to afford 3,4-dimethoxyphenyl 4-methylphenyl sulfide (3t) (39.7 mg, 61.4%) as a light yellow oil.
References
[1] Patent: WO2013/175415, 2013, A1. Location in patent: Page/Page column 46
[2] Journal of the American Chemical Society, 2015, vol. 137, # 7, p. 2665 - 2673
[3] Journal of the American Chemical Society, 2014, vol. 136, # 18, p. 6566 - 6569
[4] Journal of the American Chemical Society, 2002, vol. 124, # 3, p. 390 - 391
[5] Journal of the American Chemical Society, 2015, vol. 137, # 15, p. 5193 - 5198
3,4-DIMETHOXYPHENYLBORONIC ACID, PINACOL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
3,4-DIMETHOXYPHENYLBORONIC ACID, PINACOL ESTER Suppliers
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- Fax
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- Country
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View Lastest Price from 3,4-DIMETHOXYPHENYLBORONIC ACID, PINACOL ESTER manufacturers
- Product
- 3,4-DIMETHOXYPHENYLBORONIC ACID, PINACOL ESTER-YL) METHANAMINE 365564-10-9
- Price
- US $0.01/KG
- Min. Order
- 1KG
- Purity
- 98%; 99%
- Supply Ability
- 1kg; 5kg
- Release date
- 2020-02-03