3-PHENYL-2-(PHENYLSULFONYL)-1,2-OXAZIRIDINE
- Product Name
- 3-PHENYL-2-(PHENYLSULFONYL)-1,2-OXAZIRIDINE
- CAS No.
- 63160-13-4
- Chemical Name
- 3-PHENYL-2-(PHENYLSULFONYL)-1,2-OXAZIRIDINE
- Synonyms
- Davis Oxaziridine;2-(benzenesulfonyl)-3-phenyloxaziridine;2-OXAZIRIDINE;3-PHENYL-2-(PHENYLSULFONYL)-1;N-(Phenylsulfonyl)phenyloxaziridine;3-Phenyl-N-phenylsulfonyloxaziridine;Oxaziridine, 3-phenyl-2-(phenylsulfonyl;3-PHENYL-2-(PHENYLSULFONYL)-1,2-OXAZIRIDINE;trans-2-(Phenylsulfonyl)-3-phenyloxyaziridine;TRANS-2-(PHENYL SULFONYL)-3-PHENYL OXAZIRIDINE
- CBNumber
- CB9287428
- Molecular Formula
- C13H11NO3S
- Formula Weight
- 261.3
- MOL File
- 63160-13-4.mol
3-PHENYL-2-(PHENYLSULFONYL)-1,2-OXAZIRIDINE Property
- Melting point:
- 96-97 °C
- Boiling point:
- 394.4±45.0 °C(Predicted)
- Density
- 1.398±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Sonicated)
- form
- Solid
- pka
- -13.47±0.40(Predicted)
- color
- White to Off-White
Safety
- HS Code
- 2935909099
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D194900
- Product name
- DavisOxaziridine
- Packaging
- 1g
- Price
- $180
- Updated
- 2021/12/16
- Product number
- 8663-1-23
- Product name
- 3-Phenyl-2-(phenylsulfonyl)-1,2-oxaziridine
- Purity
- 96%
- Packaging
- 250mg
- Price
- $195
- Updated
- 2021/12/16
- Product number
- P5853
- Product name
- 3-Phenyl-2-(phenylsulfonyl)-1,2-oxaziridine
- Purity
- 95%
- Packaging
- 25g
- Price
- $280
- Updated
- 2021/12/16
- Product number
- P5853
- Product name
- 3-Phenyl-2-(phenylsulfonyl)-1,2-oxaziridine
- Purity
- 95%
- Packaging
- 250mg
- Price
- $20
- Updated
- 2021/12/16
- Product number
- P5853
- Product name
- 3-Phenyl-2-(phenylsulfonyl)-1,2-oxaziridine
- Purity
- 95%
- Packaging
- 1g
- Price
- $40
- Updated
- 2021/12/16
3-PHENYL-2-(PHENYLSULFONYL)-1,2-OXAZIRIDINE Chemical Properties,Usage,Production
Uses
Davis Oxaziridine is an oxidizing agent used in the preparation of wide variety of pharmaceutical compounds.
Uses
3-Phenyl-2-(phenylsulfonyl)-1,2-oxaziridine, is an oxidizing agent used in the preparation of wide variety of pharmaceutical compounds.
Preparation
3-PHENYL-2-(PHENYLSULFONYL)-1,2-OXAZIRIDINE can be readily prepared on a 100 g scale in 88% yield via
oxidation of N-benzylidenebenzenesulfonamide with buffered m-Chloroperbenzoic Acid or more
conveniently with Potassium Monoperoxysulfate (Oxone). This Baeyer-Villiger type of oxidation of
sulfonimine affords only the trans-oxaziridine. A number of other (±)-trans-2-(arylsulfonyl)-3-
aryloxaziridines (2) can also be prepared by these methods.
General Description
3-PHENYL-2-(PHENYLSULFONYL)-1,2-OXAZIRIDINE is a neutral, aprotic, electrophilic oxidizing agent for the chemoselective oxidation of many nucleophilic substrates[1].
storage
3-Phenyl-2-(phenylsulfonyl)-1,2-oxaziridine can be stored in a brown bottle in the refrigerator for years without noticeable decomposition. Storage at rt for long periods of time, however, is potentially hazardous.[2] The nitro-substituted oxaziridines (2) are more thermally stable and are recommended for reactions at elevated temperatures.
References
1. (a) Davis, F. A.; Sherppard, A. C. T 1989, 45, 5703. (b) Davis, F. A.; Chen, B.-C. CRV 1992, 92, 912.
2. Vishwakarma, L. C.; Stringer, O. D.; Davis, F. A. OS 1988, 66, 203.
3-PHENYL-2-(PHENYLSULFONYL)-1,2-OXAZIRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
3-PHENYL-2-(PHENYLSULFONYL)-1,2-OXAZIRIDINE Suppliers
- Tel
- --
- Fax
- --
- sales@galchimia.com
- Country
- Spain
- ProdList
- 66
- Advantage
- 60
View Lastest Price from 3-PHENYL-2-(PHENYLSULFONYL)-1,2-OXAZIRIDINE manufacturers
- Product
- 3-PHENYL-2-(PHENYLSULFONYL)-1,2-OXAZIRIDINE 63160-13-4
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98.00%
- Supply Ability
- 20tons
- Release date
- 2023-09-07
- Product
- 3-PHENYL-2-(PHENYLSULFONYL)-1,2-OXAZIRIDINE 63160-13-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98% HPLC
- Supply Ability
- 10 tons/month
- Release date
- 2020-01-07