Description Source Background
ChemicalBook > CAS DataBase List > MGC34647

MGC34647

Description Source Background
Product Name
MGC34647
Chemical Name
MGC34647
Synonyms
IL34;IL-34;C16orf77;MGC34647;IL-34 human;Monoclonal Anti-IL34 antibody produced in mouse
CBNumber
CB92912874
Formula Weight
0
MOL File
Mol file
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MGC34647 Property

storage temp. 
-20°C
form 
lyophilized
biological source
mouse
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Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26
WGK Germany 
WGK 1
Storage Class
10 - Combustible liquids
Hazard Classifications
Eye Irrit. 2
STOT SE 3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SAB5300136
Product name
Monoclonal Anti-IL34 antibody produced in mouse
Purity
clone 1D12, ascites fluid
Packaging
100 μL
Price
$580
Updated
2026/04/30
Usbiological
Product number
356797
Product name
IL34
Packaging
48Tests
Price
$588
Updated
2021/12/16
Usbiological
Product number
472402
Product name
IL-34
Packaging
96Tests
Price
$731
Updated
2021/12/16
Biorbyt Ltd
Product number
orb599951
Product name
IL34
Packaging
10μg
Price
$290.7
Updated
2021/12/16
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MGC34647 Chemical Properties,Usage,Production

Uses

IL-34 is a ligand for colony-stimulating factor-1 receptor (CSF1R), which also binds to CSF-1. It specifically binds CD14+ monocytes, promotes survival and proliferation of human peripheral blood monocytes, and stimulates macrophage colony formation by human bone marrow cells. IL-34, like human CSF-1 stimulates phosphorylation of MAPK1/ERK2 and MAPK3/ERK1.

Biological Activity

IL-34 is a homodimeric cytokine th at is expressed in a range of tissues including spleen, heart, brain, liver, kidney, lung, ovary, thymus, testis, small intestine, prostate and colon. Recombinant human IL-34 is a 52.5 kDa homodimeric glycoprotein consisting of 460 amino acid residues, including a C-terminal His-Tag.

Description

IL34 Human Recombinant produced in CHO cells is a glycosylated homodimeric polypeptide chain containing 228 amino acids and having a total molecular mass of 26kDa.
IL34 is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.

Source

CHO cells

Background

Interleukin 34 (IL34) is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor and is a part of a group of cytokines called interleukins. IL34 increases growth or survival of immune cells known as monocytes. IL34 protein obtains its activity by binding the Colony stimulating factor 1 receptor. Interleukin 34 has also a potential part in viral infection, the adaptive immune response and bone marrow cell proliferation. Furthermore, IL34 plays an important role in innate immunity and in inflammatory processes.

MGC34647 Preparation Products And Raw materials

Raw materials

Preparation Products

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MGC34647 Suppliers

Biolab Reagents
Tel
027-65279366 18108604356
Email
products@biolabreagent.com
Country
China
ProdList
9866
Advantage
58
Wuhan Peptide Core Biotechnology Co., Ltd
Tel
027-65317797 13667154760
Email
1096814016@qq.com
Country
China
ProdList
10711
Advantage
58
ACROBiosystems
Tel
13121935750
Email
jiaxin.zhao@acrobiosystems.com
Country
China
ProdList
1431
Advantage
58
CUSABIO TECHNOLOGY LLC
Tel
027-87196173
Email
cusabio@163.com
Country
China
ProdList
6066
Advantage
58
Enzo Biochem Inc
Tel
Enzo Biochem Inc. 13797054060
Email
Enzoname@qq.com
Country
China
ProdList
6174
Advantage
58
Merck KGaA
Tel
21-20338288
Email
ordercn@merckgroup.com
Country
China
ProdList
6038
Advantage
58
Beijing Biosynthesis Biotechnology Co Ltd
Tel
400-9019800
Email
sales@bioss.com.cn
Country
China
ProdList
6273
Advantage
58
Adooq Bioscience LLC
Tel
400-025-6535
Email
sales@adooq.cn
Country
China
ProdList
6215
Advantage
58
ProSpec Tany TechnoGene Ltd
Tel
972-8947-1175
Email
info@prospecbio.com
Country
China
ProdList
6874
Advantage
58
Shanghai Yubo Biotechnology Co., Ltd
Tel
021-60514606 18321282235
Email
sale1@shybsw.net
Country
China
ProdList
8062
Advantage
58

MGC34647Related Search:


  • Monoclonal Anti-IL34 antibody produced in mouse
  • IL-34
  • C16orf77
  • IL34
  • MGC34647
  • IL-34 human