ChemicalBook > CAS DataBase List > N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamide

N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamide

Product Name
N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamide
CAS No.
1580000-17-4
Chemical Name
N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamide
Synonyms
OS-3-106;OS-3-106 >=98% (HPLC);OS-3-106, 10 mM in DMSO;N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamide;Benzamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-4-(4-thiazolyl)-;N-{4-[4-(2-Methoxyphenyl)-1-piperazinyl]butyl}-4-(1,3-thiazol-4-yl)benzamide;Inhibitor,inhibit,Dopamine Receptor,HEK 293 cells,self-administration,arylamide phenylpiperazine,OS 3 106,psychostimulant addiction,cocaine,sucrose,OS3106
CBNumber
CB92973107
Molecular Formula
C25H30N4O2S
Formula Weight
450.6
MOL File
1580000-17-4.mol
More
Less

N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamide Property

Boiling point:
671.3±55.0 °C(Predicted)
Density 
1.185±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
form 
Solid
pka
14.22±0.46(Predicted)
color 
Off-white to light yellow
More
Less

Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

DC Chemicals
Product number
DC43080
Product name
OS-3-106
Purity
>98%
Packaging
250mg
Price
$950
Updated
2021/12/16
More
Less

N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamide Chemical Properties,Usage,Production

Uses

OS-3-106 is a potent, BBB-penetrated and selective dopamine D3 receptor (D3R) agonist. OS-3-106 binds with high affinity (Ki = 0.2 nM) at the D3R. OS-3-106 can be used for psychoactivator addiction research[1].

IC 50

D3 Receptor: 0.2 nM (Ki); D2 Receptor

References

[1] Cheung TH, et al. Reduction of cocaine self-administration and D3 receptor-mediated behavior by two novel dopamine D3 receptor-selective partial agonists, OS-3-106 and WW-III-55. J Pharmacol Exp Ther. 2013 Nov;347(2):410-23. DOI:10.1124/jpet.112.202911

N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamide Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamide Suppliers

CHINA 31 United Kingdom 1 United States 3 Global 35
Pharmacodia (Beijing) Co.,Ltd
Tel
+86-400-851-9921
Fax
+86-10-82826195
Email
sales@pharmacodia.com
Country
China
ProdList
2317
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
ShangHai Biochempartner Co.,Ltd
Tel
17754423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
Advantage
62
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Lynnchem
Tel
86-(0)29-85992781 17792393971
Email
info@lynnchem.com
Country
China
ProdList
4587
Advantage
58
Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4381
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32159
Advantage
58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9409
Advantage
58
Changzhou Chenhong Biotechnology Co., Ltd.
Tel
0519-85788828 13775037613
Email
sales@chemrenpharm.com
Country
China
ProdList
3600
Advantage
58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd
Tel
15317229551
Fax
QQ:3607245178
Email
15151849396@163.com
Country
China
ProdList
998
Advantage
58

1580000-17-4, N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamideRelated Search:


  • N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-4-(thiazol-4-yl)benzamide
  • OS-3-106
  • Benzamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-4-(4-thiazolyl)-
  • N-{4-[4-(2-Methoxyphenyl)-1-piperazinyl]butyl}-4-(1,3-thiazol-4-yl)benzamide
  • OS-3-106 >=98% (HPLC)
  • Inhibitor,inhibit,Dopamine Receptor,HEK 293 cells,self-administration,arylamide phenylpiperazine,OS 3 106,psychostimulant addiction,cocaine,sucrose,OS3106
  • OS-3-106, 10 mM in DMSO
  • 1580000-17-4