ChemicalBook > CAS DataBase List > Cbz-N-amido-PEG2-acid

Cbz-N-amido-PEG2-acid

Product Name
Cbz-N-amido-PEG2-acid
CAS No.
1347750-76-8
Chemical Name
Cbz-N-amido-PEG2-acid
Synonyms
CBZ-AEEP;CBZ-NH-PEG2-COOH;CBZ-NH-PEG2-acid;Cbz-NH-PEG2-C2-acid;Cbz-N-amido-PEG2-acid;CBZ-N-AMIDO-PEG2-COOH;CBZ-NH-PEG2-propionic acid;4,7,12-Trioxa-10-azatridecanoic acid, 11-oxo-13-phenyl-;3-[2-[2-(benzyloxycarbonylamino)ethoxy]ethoxy]propanoic acid;3-[2-[2-(benzyloxycarbonylamino)ethoxy]ethoxy]propanoic acid - [B82413]
CBNumber
CB93062459
Molecular Formula
C15H21NO6
Formula Weight
311.33
MOL File
1347750-76-8.mol
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Cbz-N-amido-PEG2-acid Property

storage temp. 
2-8°C
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
C227220
Product name
Cbz-N-Amido-PEG2-Acid
Packaging
10mg
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
179892
Product name
3-[2-(2-Benzyloxycarbonylamino-ethoxy)-ethoxy]-propionic acid
Purity
95%
Packaging
5g
Price
$1073
Updated
2021/12/16
Apolloscientific
Product number
BIPG1361
Product name
Cbz-N-amido-PEG2-acid
Packaging
250mg
Price
$109
Updated
2021/12/16
BroadPharm
Product number
BP-22313
Product name
Cbz-N-amido-PEG2-acid
Purity
98%
Packaging
500mg
Price
$180
Updated
2021/12/16
Apolloscientific
Product number
BIPG1361
Product name
Cbz-N-amido-PEG2-acid
Packaging
500mg
Price
$203
Updated
2021/12/16
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Cbz-N-amido-PEG2-acid Chemical Properties,Usage,Production

Description

Cbz-N-amido-PEG2-acid is a PEG linker containing a CBZ-protected amino group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The protected amine can be deprotected by acidic conditions.

Uses

Cbz-NH-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Cbz-N-amido-PEG2-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Cbz-N-amido-PEG2-acid manufacturers

LAURENT
Product
CBZ-NH-PEG2-CH2CH2COOH 1347750-76-8
Price
US $413.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2025-11-25
XIAMEN SINOPEG BIOTECH CO., LTD.
Product
3-oxo-1-phenyl-2,7,10-trioxa-4-azatridecan-13-oic acid 1347750-76-8
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2025-09-12

1347750-76-8, Cbz-N-amido-PEG2-acidRelated Search:


  • Cbz-N-amido-PEG2-acid
  • CBZ-NH-PEG2-propionic acid
  • CBZ-AEEP
  • CBZ-N-AMIDO-PEG2-COOH
  • CBZ-NH-PEG2-COOH
  • Cbz-NH-PEG2-C2-acid
  • 4,7,12-Trioxa-10-azatridecanoic acid, 11-oxo-13-phenyl-
  • CBZ-NH-PEG2-acid
  • CbzNH-PEG2-CH2CH2COOH/4,7,12-Trioxa-10-azatridecanoic acid, 11-oxo-13-phenyl-
  • 3-[2-[2-(benzyloxycarbonylamino)ethoxy]ethoxy]propanoic acid
  • 3-[2-[2-(benzyloxycarbonylamino)ethoxy]ethoxy]propanoic acid - [B82413]
  • 1347750-76-8
  • peg