ChemicalBook > CAS DataBase List > m-PEG7-aldehyde

m-PEG7-aldehyde

Product Name
m-PEG7-aldehyde
CAS No.
1058691-77-2
Chemical Name
m-PEG7-aldehyde
Synonyms
mPEG7-CHO;MPEG7-ALD;mPEG7-pAld;MPEG7-CH2CH2CHO;m-PEG9-aldehyde;m-PEG7-aldehyde;M-PEG6-aldehyde;m-PEG6-CH2CH2CHO;4,7,10,13,16,19,22-Heptaoxatricosanal;3-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanal
CBNumber
CB93062585
Molecular Formula
C16H32O8
Formula Weight
352.42
MOL File
1058691-77-2.mol
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m-PEG7-aldehyde Property

solubility 
Soluble in Water, DMSO, DCM, DMF
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
P999633
Product name
m-PEG7-aldehyde
Packaging
5mg
Price
$45
Updated
2021/12/16
TRC
Product number
P999633
Product name
m-PEG7-aldehyde
Packaging
50mg
Price
$285
Updated
2021/12/16
BroadPharm
Product number
BP-22802
Product name
m-PEG7-aldehyde
Purity
95%
Packaging
100mg
Price
$270
Updated
2021/12/16
Apolloscientific
Product number
BIPG1576
Product name
m-PEG7-aldehyde
Packaging
100mg
Price
$526
Updated
2021/12/16
BroadPharm
Product number
BP-22802
Product name
m-PEG7-aldehyde
Purity
95%
Packaging
500mg
Price
$600
Updated
2021/12/16
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m-PEG7-aldehyde Chemical Properties,Usage,Production

Description

m-PEG7-aldehyde is a PEG reagent containing an aldehyde group. Aldehyde can react with hydrazide and aminooxy groups for labeling and crosslinking carbonyls.

Biological Activity

M-PEG7-aldehyde is a non-cleavable ADC linker for antibody drug conjugate (ADC) synthesis,it is also a PEG-based PROTAC linker, which can be used for PROTAC synthesis.

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

target

Non-cleavable

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PEGs

m-PEG7-aldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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1058691-77-2, m-PEG7-aldehydeRelated Search:


  • m-PEG7-aldehyde
  • MPEG7-ALD
  • mPEG7-CHO
  • m-PEG9-aldehyde
  • MPEG7-CH2CH2CHO
  • mPEG7-pAld
  • m-PEG6-CH2CH2CHO
  • 4,7,10,13,16,19,22-Heptaoxatricosanal
  • M-PEG6-aldehyde
  • 3-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanal
  • 1058691-77-2
  • peg