3-(BROMOMETHYL)TETRAHYDROFURAN
- Product Name
- 3-(BROMOMETHYL)TETRAHYDROFURAN
- CAS No.
- 165253-29-2
- Chemical Name
- 3-(BROMOMETHYL)TETRAHYDROFURAN
- Synonyms
- 3-(Bromomethyl)oxolane;3-(Bromomethyl)tetrahydro...;3-(BROMOMETHYL)TETRAHYDROFURAN;3-Tetrahydrofurylmethyl bromide;Furan, 3-(bromomethyl)tetrahydro-;Tetrahydro-3-furanylmethyl bromide;3-(bromomethyl)tetrahydrofuran(SALTDATA: FREE)
- CBNumber
- CB9306491
- Molecular Formula
- C5H9BrO
- Formula Weight
- 165.03
- MOL File
- 165253-29-2.mol
3-(BROMOMETHYL)TETRAHYDROFURAN Property
- Boiling point:
- 183℃
- Density
- 1.447
- refractive index
- n20/D1.494
- Flash point:
- 71℃
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- liquid
- color
- Clear, yellow
- InChI
- InChI=1S/C5H9BrO/c6-3-5-1-2-7-4-5/h5H,1-4H2
- InChIKey
- AXQYVOIYCYAVSW-UHFFFAOYSA-N
- SMILES
- O1CCC(CBr)C1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 736767
- Product name
- 3-(Bromomethyl)tetrahydrofuran
- Packaging
- 250mg
- Price
- $132
- Updated
- 2023/06/20
- Product number
- 068675
- Product name
- Tetrahydro-3-furanylmethyl bromide
- Purity
- >95%
- Packaging
- 500mg
- Price
- $103
- Updated
- 2021/12/16
- Product number
- 068675
- Product name
- Tetrahydro-3-furanylmethyl bromide
- Purity
- >95%
- Packaging
- 1g
- Price
- $159
- Updated
- 2021/12/16
- Product number
- 8390AA
- Product name
- 3-(Bromomethyl)tetrahydrofuran
- Packaging
- 100mg
- Price
- $242
- Updated
- 2021/12/16
- Product number
- 2H10-9-16
- Product name
- 3-(Bromomethyl)oxolane
- Packaging
- 1g
- Price
- $376
- Updated
- 2021/12/16
3-(BROMOMETHYL)TETRAHYDROFURAN Chemical Properties,Usage,Production
Uses
3-(Bromomethyl)oxolane is used as a reagent in the preparation of thiazoleurea derivatives for use as antitumor agents.
Synthesis
184849-49-8
165253-29-2
Step 2: Synthesis of 3-(bromomethyl)tetrahydrofuran Lithium bromide (13.6 g) was added to a solution of methyl methanesulfonate (tetrahydrofuran-3-yl) methyl ester (5.6 g) in acetone (80 mL). The reaction mixture was heated to reflux for 4 hours. Upon completion of the reaction, the solvent was removed by rotary evaporator under reduced pressure. The residue was subjected to liquid-liquid partitioning with dichloromethane and water. The organic phase was separated and dried with anhydrous magnesium sulfate. After filtration, the dichloromethane was removed by evaporation. The resulting residue was dissolved in a small amount of dichloromethane and purified by filtration through a short column of silica gel. Finally, the filtrate was concentrated to give the title compound 3-(bromomethyl)tetrahydrofuran. Yield: 3.9 g; TLC detection: Rf = 0.80 (silica gel plate, unfolding agent was cyclohexane/ethyl acetate, 1:1 volume ratio).
References
[1] Patent: WO2004/5293, 2004, A2. Location in patent: Page 69
[2] Patent: WO2006/23630, 2006, A2. Location in patent: Page/Page column 39; 65
[3] Patent: US2013/252937, 2013, A1. Location in patent: Paragraph 0432
[4] Patent: WO2013/144097, 2013, A1. Location in patent: Page/Page column 74
[5] Patent: WO2013/144098, 2013, A1. Location in patent: Page/Page column 111
3-(BROMOMETHYL)TETRAHYDROFURAN Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-(BROMOMETHYL)TETRAHYDROFURAN manufacturers
- Product
- 3-(BROMOMETHYL)TETRAHYDROFURAN 165253-29-2
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-03-28
- Product
- 3-(Bromomethyl)tetrahydrofuran 165253-29-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 500kg
- Release date
- 2018-08-16