ChemicalBook > CAS DataBase List > 1-(2-Amino-5-hydroxyphenyl)propan-1-one
1-(2-Amino-5-hydroxyphenyl)propan-1-one
- Product Name
- 1-(2-Amino-5-hydroxyphenyl)propan-1-one
- CAS No.
- 35364-15-9
- Chemical Name
- 1-(2-Amino-5-hydroxyphenyl)propan-1-one
- Synonyms
- aminoketone;2-Amino-5-Hydroxy propiophenone;2'-amino-5'-hydroxypropiophenone;1-(2-Amino-5-hydroxyphenyl)-1-propanone;1-propanone,1-(2-amino-5-hydroxyhenyl)-;1-(2-Amino-5-hydroxyphenyl)propan-1-one;1-Propanone, 1-(2-amino-5-hydroxyphenyl)-
- CBNumber
- CB93070610
- Molecular Formula
- C9H11NO2
- Formula Weight
- 165.19
- MOL File
- 35364-15-9.mol
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1-(2-Amino-5-hydroxyphenyl)propan-1-one Property
- Melting point:
- 144.5-144.9 °C
- Boiling point:
- 363.9±32.0 °C(Predicted)
- Density
- 1.195±0.06 g/cm3(Predicted)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 9.35±0.18(Predicted)
- color
- Light Yellow to Brown
- Stability:
- Hygroscopic
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N-Bromosuccinimide Price
TRC
- Product number
- A611480
- Product name
- 1-(2-Amino-5-hydroxyphenyl)propan-1-one
- Packaging
- 2.5g
- Price
- $1295
- Updated
- 2021/12/16
AK Scientific
- Product number
- 5920CS
- Product name
- 1-(2-Amino-5-hydroxyphenyl)propan-1-one
- Packaging
- 25mg
- Price
- $252
- Updated
- 2021/12/16
AK Scientific
- Product number
- 5920CS
- Product name
- 1-(2-Amino-5-hydroxyphenyl)propan-1-one
- Packaging
- 250mg
- Price
- $455
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0291115
- Product name
- 2-AMINO-5-HYDROXYPROPIOPHENONE
- Purity
- 95.00%
- Packaging
- 0.5G
- Price
- $726
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0291115
- Product name
- 2-AMINO-5-HYDROXYPROPIOPHENONE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $808.5
- Updated
- 2021/12/16
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1-(2-Amino-5-hydroxyphenyl)propan-1-one Chemical Properties,Usage,Production
Uses
1-(2-Amino-5-hydroxyphenyl)propan-1-one is a useful synthetic intermediate. It is used in the asymmetrical synthesis of (S)-4-ethyl-6,7,8,10- tetrahydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione, a key intermediate for synthesis of irinotecan and other camptothecin analogs. It is also used in the synthesis of E-?ring-?modified (RS)?-?camptothecin analogs as antitumor agents.
Preparation
Obtained by UV-irradiation of 3-ethyl-2,1-benzisoxazole in 66% sulfuric acid for 90 min at 80–90°
Also prepared from 2-nitro-5-hydroxybenzaldehyde (five steps) or from p-anisidine.
1-(2-Amino-5-hydroxyphenyl)propan-1-one Preparation Products And Raw materials
Raw materials
Preparation Products
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