ChemicalBook > CAS DataBase List > 4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate

4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate

Product Name
4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate
CAS No.
202189-76-2
Chemical Name
4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate
Synonyms
Bilastine ITS-1;*Mesna Impurity 16;Bilastine impurity C;Bilastine Impurity 03;Pilastine impurity 21;Bilastine ITS-1,Bilastine intermediate;2-[4-[1-(4,4-Dimethyl-5H-Oxazol-2-Yl)-1- Methyl-Ethyl]Phenyl;4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate;2-[4-[1-(4,4-dimethyl-5H-oxazol-2-yl)-1-methyl-ethyl]phenyl]ethyl 4-methylbenzenesulfonate;4-(2-((4,4-dimethyl-4,5-dihydroxyoxazol-2-yl)propan-2yl)phenethyl-4-methylbenzenesulfonate
CBNumber
CB93076733
Molecular Formula
C23H29NO4S
Formula Weight
415.55
MOL File
202189-76-2.mol
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4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate Property

Boiling point:
545.1±45.0 °C(Predicted)
Density 
1.14±0.1 g/cm3(Predicted)
vapor pressure 
0Pa at 25℃
storage temp. 
2-8°C
solubility 
soluble in Dichloromethane;
pka
5.78±0.70(Predicted)
Water Solubility 
5.717μg/L at 25℃
InChI
InChI=1S/C23H29NO4S/c1-17-6-12-20(13-7-17)29(25,26)28-15-14-18-8-10-19(11-9-18)23(4,5)21-24-22(2,3)16-27-21/h6-13H,14-16H2,1-5H3
InChIKey
BGUOPDZOVDIWLE-UHFFFAOYSA-N
SMILES
C(C1C=CC(CCOS(C2C=CC(C)=CC=2)(=O)=O)=CC=1)(C1OCC(C)(C)N=1)(C)C
LogP
6.6
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific
Product number
8683BB
Product name
4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl4-methylbenzenesulfonate
Packaging
5g
Price
$165
Updated
2021/12/16
Ambeed
Product number
A176690
Product name
4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl4-methylbenzenesulfonate
Purity
97%
Packaging
250mg
Price
$10
Updated
2021/12/16
Ambeed
Product number
A176690
Product name
4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl4-methylbenzenesulfonate
Purity
97%
Packaging
5g
Price
$78
Updated
2021/12/16
Alichem
Product number
202189762
Product name
4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl4-methylbenzenesulfonate
Packaging
5g
Price
$176
Updated
2021/12/16
Crysdot
Product number
CD11169316
Product name
4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl4-methylbenzenesulfonate
Purity
97%
Packaging
10g
Price
$257
Updated
2021/12/16
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4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate Chemical Properties,Usage,Production

Uses

4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate (or Benzeneethanol, 4-[1-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-1-methylethyl]-, 4-methylbenzenesulfonate (ester)) is an intermediate used in the synthesis of Bilastine-d6 (B385002), which is labelled Bilastine. It is a novel, nonsedating H1-antihistamine developed for symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria.

4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate Suppliers

Anhui Dexinjia Biopharm Co., Ltd
Tel
0531-82375892 15562613975
Email
3416953599@qq.com
Country
China
ProdList
309
Advantage
58
Shanghai Joiny Pharmaceutical Co.,Ltd.
Tel
13681955282
Email
gyd@joiny-pharma.com
Country
China
ProdList
216
Advantage
58
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Shanghai Boc Chemical Co.,Ltd
Tel
021-34975603-808 18721111801
Fax
+86-21-34975602-805
Email
sales@bocpharma.com
Country
China
ProdList
997
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64
Changzhou Wanyao Biotechnology Co., Ltd.
Tel
0519-89185693 15312551983
Fax
0519-89185693
Email
2410037592@qq.com
Country
China
ProdList
299
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55
Beijing Comparison Pharmaceutical Technology Co., Ltd
Tel
010-010-52878169 15801002657
Email
sales@bjcomparison.com
Country
China
ProdList
5004
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58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
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60
Porse Fine Chemical Co.,LTD
Tel
20-66003216 18666003216
Fax
+86-20-28069063
Email
info@porsefinechemical.com
Country
China
ProdList
2353
Advantage
62
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18070
Advantage
56
Shanghai Send Pharmaceutical Technology Co., Ltd.
Tel
021-58088081 Q3382968513
Fax
QQ3382968513
Email
hailey@shsendpharm.com
Country
China
ProdList
3129
Advantage
55
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View Lastest Price from 4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate manufacturers

Anhui Dexinjia Biopharm Co., Ltd
Product
Benzeneethanol, 4-[1-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-1-methylethyl]-, 4-methylbenzenesulfonate (ester) 202189-76-2
Price
US $500.00-8000.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000kg per month
Release date
2023-03-23
Shanghai Joiny Pharmaceutical Co.,LTD
Product
2-[4-[1-(4,4-dimethyl-5H-oxazol-2-yl)-1 methyl-ethyl] phenyl]ethyl 4-methylbenzenesulfonate 202189-76-2
Price
US $0.00/kg
Min. Order
1kg
Purity
96%
Supply Ability
200kg
Release date
2022-12-13
Career Henan Chemical Co
Product
Benzeneethanol, 4-[1-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-1-methylethyl]-, 4-methylbenzenesulfonate (ester) 202189-76-2
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-01-09

202189-76-2, 4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonateRelated Search:


  • Benzeneethanol, 4-[1-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-1-methylethyl]-, 4-methylbenzenesulfonate (ester)
  • 4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate
  • 2-[4-[1-(4,4-dimethyl-5H-oxazol-2-yl)-1-methyl-ethyl]phenyl]ethyl 4-methylbenzenesulfonate
  • Bilastine impurity C
  • 2-[4-[1-(4,4-Dimethyl-5H-Oxazol-2-Yl)-1- Methyl-Ethyl]Phenyl
  • Benzeneethanol, 4-[1-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-1-methylethyl]-, 1-(4-methylbenzenesulfonate)
  • 4 - (2 - (4,4-dimethyl-4,5-dihydroxazol-2-yl) propyl-2-yl) phenylethyl 4-methylbenzene sulfonate
  • 4-(2-((4,4-dimethyl-4,5-dihydroxyoxazol-2-yl)propan-2yl)phenethyl-4-methylbenzenesulfonate
  • 2-{4-[2-(4,4-dimethyl-4,5-dihydro-1,3-oxazol-2-yl)propan-2-yl]phenyl}ethyl 4-methylbenzene-1-sulfonate
  • Bilastine ITS-1
  • Bilastine ITS-1,Bilastine intermediate
  • 2-(4-(2-(4-(1-(2-hydroxyethyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)ethyl)phenyl)-2-methylpropanoic acid hydrochloride
  • 2-(4-[1-(4,4-Dimethyl-4,5-dihydro-oxazol-2-yl)-1-methyl-ethyl]-phenyl)-ethyl toluene-4-sulfonate
  • *Mesna Impurity 16
  • Bilastine Impurity 03
  • Pilastine impurity 21
  • 202189-76-2