ChemicalBook > CAS DataBase List > 4-[6-[(8-Cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carboxylic acid tert-butyl ester

4-[6-[(8-Cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carboxylic acid tert-butyl ester

Product Name
4-[6-[(8-Cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carboxylic acid tert-butyl ester
CAS No.
571189-65-6
Chemical Name
4-[6-[(8-Cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carboxylic acid tert-butyl ester
Synonyms
Palbociclib-009;Palbociclib Impurity 97;Palbociclib Impuirty-15;6-Desacetyl-N-Boc Palbociclib;Palbociclib Impurity 15Q: What is Palbociclib Impurity 15 Q: What is the CAS Number of Palbociclib Impurity 15;tert - butyl 4- ( 6 - ( ( 8 - cyclopentyl - 5 - methyl - 7 - oxo - 7,8 - dihydropyrido [ 2,3 - d ] pyrimidin - 2 - yl );4-[6-[(8-Cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carboxylic acid tert-butyl ester;1-Piperazinecarboxylic acid, 4-[6-[(8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-, 1,1-dimethylethyl ester;tert-Butyl 4-(6-((8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate? (Palbociclib Impurity);Palbociclib impurity 11/4-[6-[(8-Cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2- yl)amino]pyridin-3-yl]piperazine-1-carboxylic acid tert-butyl ester
CBNumber
CB93158750
Molecular Formula
C27H35N7O3
Formula Weight
505.61
MOL File
571189-65-6.mol
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4-[6-[(8-Cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carboxylic acid tert-butyl ester Property

Melting point:
>209°C (dec.)
Boiling point:
691.5±65.0 °C(Predicted)
Density 
1.284±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator, Under inert atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly, Heated), Dichloromethane
pka
5.24±0.10(Predicted)
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D288713
Product name
6-Desacetyl-N-BocPalbociclib
Packaging
1mg
Price
$165
Updated
2021/12/16
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4-[6-[(8-Cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carboxylic acid tert-butyl ester Chemical Properties,Usage,Production

Uses

6-Desacetyl N-Boc Palbociclib is an impurity of Palbociclib (P139900),(also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.

4-[6-[(8-Cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carboxylic acid tert-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[6-[(8-Cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carboxylic acid tert-butyl ester Suppliers

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571189-65-6, 4-[6-[(8-Cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carboxylic acid tert-butyl esterRelated Search:


  • 4-[6-[(8-Cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carboxylic acid tert-butyl ester
  • Palbociclib-009
  • Palbociclib impurity 11/4-[6-[(8-Cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2- yl)amino]pyridin-3-yl]piperazine-1-carboxylic acid tert-butyl ester
  • 1-Piperazinecarboxylic acid, 4-[6-[(8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-, 1,1-dimethylethyl ester
  • 6-Desacetyl-N-Boc Palbociclib
  • tert-Butyl 4-(6-((8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate? (Palbociclib Impurity)
  • Palbociclib Impurity 97
  • Palbociclib Impurity 15Q: What is Palbociclib Impurity 15 Q: What is the CAS Number of Palbociclib Impurity 15
  • Palbociclib Impuirty-15
  • tert - butyl 4- ( 6 - ( ( 8 - cyclopentyl - 5 - methyl - 7 - oxo - 7,8 - dihydropyrido [ 2,3 - d ] pyrimidin - 2 - yl )
  • 571189-65-6
  • C27H35N7O3