m-PEG3-S-PEG4-propargyl
- Product Name
- m-PEG3-S-PEG4-propargyl
- CAS No.
- 2055040-85-0
- Chemical Name
- m-PEG3-S-PEG4-propargyl
- Synonyms
- m-PEG3-S-PEG4-propargyl;2,5,8,14,17,20,23-Heptaoxa-11-thiahexacos-25-yne
- CBNumber
- CB93163011
- Molecular Formula
- C18H34O7S
- Formula Weight
- 394.52
- MOL File
- 2055040-85-0.mol
m-PEG3-S-PEG4-propargyl Property
- Boiling point:
- 462.5±45.0 °C(Predicted)
- Density
- 1.072±0.06 g/cm3(Predicted)
N-Bromosuccinimide Price
- Product number
- BP-23166
- Product name
- m-PEG3-S-PEG4-propargyl
- Purity
- 98%
- Packaging
- 500mg
- Price
- $680
- Updated
- 2021/12/16
m-PEG3-S-PEG4-propargyl Chemical Properties,Usage,Production
Description
m-PEG3-S-PEG4-propargyl is a PEG linker containing a propargyl group. The propargyl groups can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
m-PEG3-S-PEG4-propargyl is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. m-PEG3-S-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005
m-PEG3-S-PEG4-propargyl Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from m-PEG3-S-PEG4-propargyl manufacturers
- Product
- m-PEG3-S-PEG4-propargyl 2055040-85-0
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >95.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-28