4-ISOPROPOXYBENZALDEHYDE

Product Name: 4-ISOPROPOXYBENZALDEHYDE
CAS No.: 18962-05-5
Chemical Name: 4-ISOPROPOXYBENZALDEHYDE
Synonyms: NSC 69072;AKOS 226-45;AKOS BC-2523;AKOS B000275;ALDH1A3-IN-3;ASISCHEM R42745;BUTTPARK 32\08-27;4-IsopropoxybenzaL;4-ISOPROPOXYBENZALDEHYDE;p-Isopropoxybenzaldehyde
CBNumber: CB9318261
Molecular Formula: C10H12O2
Formula Weight: 164.2
MOL File: 18962-05-5.mol

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4-ISOPROPOXYBENZALDEHYDE Property

Melting point:: 167 °C
Boiling point:: 108-110 °C (5 mmHg)
Density: 1.036
refractive index: 1.545-1.547
Flash point:: 108-110°C/5mm
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: clear liquid
color: Colorless to Light orange to Yellow
Sensitive: Air Sensitive
BRN: 742921
InChI: InChI=1S/C10H12O2/c1-8(2)12-10-5-3-9(7-11)4-6-10/h3-8H,1-2H3
InChIKey: WDANSDASCKBVKH-UHFFFAOYSA-N
SMILES: C(=O)C1=CC=C(OC(C)C)C=C1
CAS DataBase Reference: 18962-05-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 37/39-26-36
HazardClass: IRRITANT
HS Code: 2912490090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: I0949
Product name: 4-Isopropoxybenzaldehyde
Purity: >96.0%(GC)
Packaging: 5g
Price: $48
Updated: 2025/07/31

TCI Chemical

Product number: I0949
Product name: 4-Isopropoxybenzaldehyde
Purity: >96.0%(GC)
Packaging: 25g
Price: $167
Updated: 2025/07/31

TRC

Product number: I779023
Product name: 4-Isopropoxybenzaldehyde
Packaging: 250mg
Price: $45
Updated: 2021/12/16

AK Scientific

Product number: J52199
Product name: 4-Isopropoxybenzaldehyde
Packaging: 1g
Price: $10
Updated: 2021/12/16

Matrix Scientific

Product number: 028456
Product name: 4-Isopropoxybenzaldehyde
Purity: 95+%
Packaging: 5g
Price: $17
Updated: 2021/12/16

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4-ISOPROPOXYBENZALDEHYDE Chemical Properties,Usage,Production

Chemical Properties

clear colorless to yellow liquid

Uses

ALDH1A3-IN-3 (compound 16) is a potent inhibitor of ALDH1A3, with an IC50 of 0.26 μM. ALDH1A3-IN-3 is also a good ALDH3A1 substrate. ALDH1A3-IN-3 can be used for the research of prostate cancer[1].

Synthesis

75-30-9

123-08-0

18962-05-5

General procedure for the synthesis of 4-isopropoxybenzaldehyde from 2-iodopropane and p-hydroxybenzaldehyde: Referring to Example 3, to a 100 mL DMF solution containing 2 g (16.38 mmol) of p-hydroxybenzaldehyde was added sequentially 2.72 g (19.69 mmol) of K2CO3, 2.74 g (16.52 mmol) of KI, and 3.94 mL ( 39.38 mmol) 2-iodopropane and the reaction was carried out under argon protection. The reaction mixture was stirred at 80 °C overnight and subsequently concentrated. The concentrated residue was partitioned between CHCl3 and H2O to separate the organic and aqueous phases. The aqueous phase was further extracted with CHCl3 and after combining all the organic phases was dried and concentrated with MgSO4. The crude product was purified by silica gel column chromatography using a gradient polarity EtOAc/hexane mixed solvent as eluent, resulting in 2.08 g of oily 4-isopropoxybenzaldehyde in 77% yield. The structure of the product was confirmed by 1H-NMR (300 MHz, CDCl3, δTMS): 1.39 (d, J=6Hz, 6H), 4.67 (m, 1H), 6.96 (d, J=8.7Hz, 2H), 7.81 (d, J=8.7Hz, 2H), 9.87 (s, 1H).

IC 50

ALDH3; ALDH1

References

[1] Ibrahim AIM, et, al. Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer. J Med Chem. 2022 Mar 10;65(5):3833-3848. DOI:10.1021/acs.jmedchem.1c01367

4-ISOPROPOXYBENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-ISOPROPOXYBENZALDEHYDE Suppliers

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View Lastest Price from 4-ISOPROPOXYBENZALDEHYDE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-ISOPROPOXYBENZALDEHYDE 18962-05-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-ISOPROPOXYBENZALDEHYDE 18962-05-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: 4-(Isopropyloxy)benzaldehyde 18962-05-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200KG
Release date: 2020-01-09

18962-05-5, 4-ISOPROPOXYBENZALDEHYDERelated Search:

4-ISOPROPOXYBENZOIC ACID P-CYCLOHEXYLOXYBENZOIC ACID 2,2-DIMETHYLCHROMANE-6-CARBALDEHYDE 4-ISOPROPOXYBENZALDEHYDE Rotenone 4-(TERT-BUTOXY)BENZALDEHYDE 2-ISO-PROPOXYBENZALDEHYDE 4-(TERT-BUTOXY)BENZOIC ACID OSAJIN ISO-OSAJIN 2-(4-CARBOXYPHENOXY)-2-PIVALOYL-2',4'-DICHLOROACETANILIDE 4-ISO-PROPOXY-BENZOYL CHLORIDE 4-ISOPROPOXYBENZOIC ACID METHYL ESTER 3-CHLORO-5-ETHOXY-4-ISOPROPOXYBENZALDEHYDE 5-CHLORO-2-ISOPROPOXYBENZALDEHYDE 3-BROMO-4-ISOPROPOXYBENZALDEHYDE 3-ALLYL-5-ETHOXY-4-ISOPROPOXYBENZALDEHYDE 5-bromo-3-iodo-2-isopropoxybenzaldehyde

ASISCHEM R42745

BUTTPARK 32\08-27

4-ISOPROPOXYBENZALDEHYDE

AKOS B000275

AKOS 226-45

AKOS BC-2523

4-ISOPROPOXY-1-FORMYLBENZENE

4-Isopropoxybenzaldehyde,98%

4-isopropoxybenzaldehyde(SALTDATA: FREE)

4-(1-Methylethoxy)benzaldehyde

4-(Isopropyloxy)benzaldehyde

4-(Propan-2-yloxy)benzaldehyde

4-[(1-Methylethyl)oxy]benzaldehyde

NSC 69072

p-(Isopropyloxy)benzaldehyde

p-Isopropoxybenzaldehyde

4-IsopropoxybenzaL

4-Isopropoxybenzaldehyde &gt

Benzaldehyde, 4-(1-methylethoxy)-

ALDH1A3-IN-3

18962-05-5

18962-05-0

18963-05-5

ALDEHYDE

Aromatic Aldehydes & Derivatives (substituted)