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2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER

Product Name
2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER
CAS No.
118-57-0
Chemical Name
2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER
Synonyms
SALOPHEN;Asalphen;Phenestal;Cetosalol;Phenetsal;acetaminosalol;p-Acetamidophenyl salicylate;4-acetamidophenyl salicylate;4-Acetaminophenyl salicylate;ACETYL-P-AMINOPHENYLSALICYLATE
CBNumber
CB9322358
Molecular Formula
C15H13NO4
Formula Weight
271.27
MOL File
118-57-0.mol
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2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER Property

Melting point:
187°
Stability:
Stable. Incompatible with strong oxidizing agents.
LogP
2.562 (est)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S598038
Product name
4-ACETAMIDOPHENYL SALICYLATE
Purity
AldrichCPR
Packaging
250MG
Price
$179
Updated
2024/03/01
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2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER Chemical Properties,Usage,Production

Chemical Properties

solid

Originator

Acetaminosal ,ZYF Pharm Chemical

Uses

Analgesic; antipyretic.

Definition

ChEBI: Acetaminosalol is a carbonyl compound.

Manufacturing Process

2 Methods of producing of acetyl salicylic acid ester of N-acetyl-paminophenol:
1. 65.0 g of N-acetyl-p-aminophenol were slurried with 400 ml of water and cooled to 10°C. 125 ml of 20% sodium hydroxide were slowly added to the mixture with stirring, the temperature being maintained 10°-15°C. To the solution obtained, 75.0 g of acetyl salicylic chloride were added with vigorous stirring over a period of 0.5 h, the solution being maintained at a temperature of about 10°C. Towards the end of the reaction the pH was checked and adjusted to greater than 10 by the addition of a small amount of 20% sodium hydroxide. After all the acid chloride had been added, vigorous stirring was continued for 0.5 h during which time the crude product separated out. The acetyl salicylic acid ester of N-acetyl-p-aminophenol was filtered off, washed thoroughly with water and recrystallised from ethanol.
2. 65.0 g of sodium N-acetyl-p-aminophenol were slurried with 500.0 g of dry benzene and 80.0 g of acetyl salicylic chloride added. The mixture was heated under reflux for 4 h and filtered hot. The excess benzene was removed under vacuum and the crude acetyl salicylic acid ester of N-acetyl-p-aminophenol crystallized from ethanol.

brand name

Acephen (G & W); Infants’ Feverall (Actavis); Injectapap (Ortho-McNeil); Neopap (Polymedica); Tylenol (McNeil).

Therapeutic Function

Analgesic, Antineuralgic, Antirheumatic, Antipyretic

2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER Suppliers

SynAsst Chemical.
Tel
021-60343070
Fax
021-35122006
Country
China
ProdList
12740
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Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
22784
Advantage
58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
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58
Shandong WorldSun Biological Technology Co., Ltd.
Tel
0531-88723173 18596073690
Email
1047208234@qq.com
Country
China
ProdList
4682
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Shaanxi Dideu Medichem Co. Ltd
Tel
029-61856358 15229202216
Fax
029-88380327
Email
1020@dideu.com
Country
China
ProdList
10011
Advantage
58
LGC Science (Shanghai) Ltd.
Tel
17717235263
Email
cindy.yang@lgcgroup.com
Country
China
ProdList
15583
Advantage
58
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View Lastest Price from 2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER manufacturers

Dideu Industries Group Limited
Product
2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER 118-57-0
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-06-16

118-57-0, 2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTERRelated Search:


  • SALOPHEN
  • ACETYL-P-AMINOPHENYLSALICYLATE
  • 2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER
  • 4-acetamidophenyl salicylate
  • acetaminosalol
  • p-Acetamidophenyl salicylate
  • Phenetsal
  • Asalphen
  • Cetosalol
  • Phenestal
  • Salicylic acid 4-(acetylamino)phenyl
  • Salicylic acid 4-(acetylamino)phenyl ester
  • (4-acetamidophenyl) 2-hydroxybenzoate
  • 2-hydroxybenzoic acid (4-acetamidophenyl) ester
  • 4-Acetaminophenyl salicylate
  • Benzoic acid, 2-hydroxy-, 4-(acetylamino)phenyl ester
  • 2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER USP/EP/BP
  • 118-57-0
  • C6H4OHCOOC6H4NHCOCH3