ChemicalBook > CAS DataBase List > IMIDAZO[1,2-B]PYRIDAZINE, 6-CHLORO-2-METHYL-

IMIDAZO[1,2-B]PYRIDAZINE, 6-CHLORO-2-METHYL-

Product Name
IMIDAZO[1,2-B]PYRIDAZINE, 6-CHLORO-2-METHYL-
CAS No.
14793-00-1
Chemical Name
IMIDAZO[1,2-B]PYRIDAZINE, 6-CHLORO-2-METHYL-
Synonyms
6-chloro-2-Methyl-iMidazopyridazine;2-Methyl-6-chloroiMidazo[1,2-b]pyridazine;6-CHLORO-2-METHYLIMIDAZO[1,2-B]PYRIDAZINE;IMIDAZO[1,2-B]PYRIDAZINE, 6-CHLORO-2-METHYL-;6-chloro-2-methylimidazo[1,2-b]pyridazine 97%;6-chloro-2-Methly-iMidazo [1, 2-b] pyridazine
CBNumber
CB9322464
Molecular Formula
C7H6ClN3
Formula Weight
167.6
MOL File
14793-00-1.mol
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IMIDAZO[1,2-B]PYRIDAZINE, 6-CHLORO-2-METHYL- Property

Density 
1.43
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
4.70±0.30(Predicted)
Appearance
White to off-white Solid
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC
Product number
C602140
Product name
6-Chloro-2-methylimidazo[1,2-b]pyridazine
Packaging
100mg
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC139441
Product name
6-Chloro-2-methylimidazo[1,2-b]pyridazine
Packaging
2g
Price
$85
Updated
2021/12/16
Matrix Scientific
Product number
119025
Product name
6-Chloro-2-methylimidazo[1,2-b]pyridazine
Purity
95+%
Packaging
250mg
Price
$202
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-5-GJ
Product name
6-Chloro-2-methylimidazo[1,2-b]pyridazine
Purity
97%
Packaging
1g
Price
$224
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC139441
Product name
6-Chloro-2-methylimidazo[1,2-b]pyridazine
Packaging
5G
Price
$362
Updated
2021/12/16
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IMIDAZO[1,2-B]PYRIDAZINE, 6-CHLORO-2-METHYL- Chemical Properties,Usage,Production

Synthesis

5469-69-2

78-95-5

14793-00-1

The general procedure for the synthesis of 6-chloro-2-methylimidazo[1,2-b]pyridazine from 3-amino-6-chloropyridazine and chloroacetone is as follows: to a solution of ethanol (15 mL) containing 6-chloropyridazin-3-amine (2.35 g, 18.1 mmol, 1.0 equiv.) was added sequentially 1-chloro-2-propanone (2.92 mL, 36.3 mmol, 2.0 equiv.) and triethylamine (2.53 mL, 18.1 mmol, 1.0 equiv). The reaction mixture was heated at 150 °C for 30 min and quenched with water upon completion of the reaction. The crude product was purified by column chromatography using a hexane solution of 30% ethyl acetate as eluent, resulting in 2.43 g of brown solid product in 80% yield.

References

[1] Patent: US2014/256733, 2014, A1. Location in patent: Paragraph 0266-0268
[2] Journal of Heterocyclic Chemistry, 1993, vol. 30, # 5, p. 1365 - 1372
[3] Patent: WO2016/97347, 2016, A1. Location in patent: Page/Page column 113
[4] Organic Process Research and Development, 2013, vol. 17, # 2, p. 273 - 281
[5] Patent: WO2009/60197, 2009, A1. Location in patent: Page/Page column 103

IMIDAZO[1,2-B]PYRIDAZINE, 6-CHLORO-2-METHYL- Preparation Products And Raw materials

Raw materials

Preparation Products

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IMIDAZO[1,2-B]PYRIDAZINE, 6-CHLORO-2-METHYL- Suppliers

A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from IMIDAZO[1,2-B]PYRIDAZINE, 6-CHLORO-2-METHYL- manufacturers

Shanghai Rlavie Technology Co ltd
Product
2-Methyl-6-chloroiMidazo[1,2-b]pyridazine 14793-00-1
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
98%minHPLC
Supply Ability
10kgs/month
Release date
2021-11-09
Career Henan Chemical Co
Product
IMIDAZO[1,2-B]PYRIDAZINE, 6-CHLORO-2-METHYL- 14793-00-1
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
200KG
Release date
2018-12-23