ChemicalBook > CAS DataBase List > Methyl 2-amino-3-chlorobenzoate

Methyl 2-amino-3-chlorobenzoate

Application

Product Name: Methyl 2-amino-3-chlorobenzoate
CAS No.: 77820-58-7
Chemical Name: Methyl 2-amino-3-chlorobenzoate
Synonyms: 2-amino-3-chloroben;Methyl 3-chloroanthranilate;2-amino-3-chlorobenzate ester;METHYL 2-AMINO-3-CHLOROBENZOATE;METHYL 3-CHLORO-2-AMINOBENZOATE;2-Amino-3-chlorbenzoesuremethylester;3-CHLOROANTHRANILIC ACID, METHYL ESTER;2-Amino-3-ChlorobenzonicAcidMethylEster;2-AMINO-3-CHLORO-BENZOIC ACID METHYL ESTER;Benzoic acid, 2-amino-3-chloro-, methyl ester
CBNumber: CB9324266
Molecular Formula: C8H8ClNO2
Formula Weight: 185.61
MOL File: 77820-58-7.mol

Less

Methyl 2-amino-3-chlorobenzoate Property

Melting point:: 35-37°C
Boiling point:: 273.8±20.0 °C(Predicted)
Density: 1.311±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: powder to lump
pka: 0.25±0.10(Predicted)
color: White to Light yellow
InChI: InChI=1S/C8H8ClNO2/c1-12-8(11)5-3-2-4-6(9)7(5)10/h2-4H,10H2,1H3
InChIKey: MSXSZFYRADEEJA-UHFFFAOYSA-N
SMILES: C(OC)(=O)C1=CC=CC(Cl)=C1N
CAS DataBase Reference: 77820-58-7(CAS DataBase Reference)
EPA Substance Registry System: Benzoic acid, 2-amino-3-chloro-, methyl ester (77820-58-7)

Less

Safety

Hazard Codes: Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36/37/39
HS Code: 2922390090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: M3074
Product name: Methyl 2-Amino-3-chlorobenzoate
Purity: >98.0%(GC)
Packaging: 1g
Price: $20
Updated: 2025/07/31

TCI Chemical

Product number: M3074
Product name: Methyl 2-Amino-3-chlorobenzoate
Purity: >98.0%(GC)
Packaging: 5g
Price: $80
Updated: 2025/07/31

TRC

Product number: M331238
Product name: Methyl 2-Amino-3-chlorobenzoate
Packaging: 250mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 076127
Product name: Methyl 2-amino-3-chlorobenzoate
Purity: 95+%
Packaging: 100g
Price: $559
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H58-5-89
Product name: Methyl 2-Amino-3-chlorobenzoate
Packaging: 1g
Price: $612
Updated: 2021/12/16

Less

Methyl 2-amino-3-chlorobenzoate Chemical Properties,Usage,Production

Application

Methyl 2-amino-3-chlorobenzoate is an important pharmaceutical and chemical intermediate. It is a key intermediate in the synthesis of the triazolidinesulfonamide herbicide chlorpyrifos and is used in the synthesis of many pesticides.

Chemical Properties

off-white crystalline powder

Synthesis

42087-81-0

77820-58-7

The general procedure for the synthesis of methyl 2-amino-3-chlorobenzoate from methyl 2-nitro-3-chlorobenzoate was as follows: iron powder (1.94 g, 34.8 mmol) was added to an ethanol/acetic acid (100 mL/100 mL) solution of methyl 3-chloro-2-nitrobenzoate (2.5 g, 11.6 mmol) at room temperature. Subsequently, the suspension was refluxed for 2 h under nitrogen protection. After completion of the reaction, it was cooled to room temperature and the solvent was partially removed by rotary evaporator. The resulting residue was partitioned between water/ethyl acetate (200 mL/300 mL). The organic phase was separated and washed sequentially with 1N aqueous sodium hydroxide (50 mL), brine (50 mL), dried over anhydrous magnesium sulfate, and concentrated by rotary evaporator to afford the target product, methyl 2-amino-3-chlorobenzoate, as a tan oily substance (1.7 g, 79% yield), which was converted to a waxy solid upon standing. The crude product was pure enough to be used in subsequent steps without further purification. The product was confirmed by 1H NMR (400 MHz, CDCl3): δ 3.86 (s, 3H), 6.25 (s, 2H), 6.57 (t, J = 7.93 Hz, 1H), 7.39 (dd, J = 7.81, 1.51 Hz, 1H), 7.79 (dd, J = 8.06, 1.51 Hz, 1H). Mass spectrometry analysis showed a molecular ion peak of 185.95 (MH+) and a calculated value of 185.02 for C8H8ClNO2.

Toxics Screening Level

The ITSL for Methyl 2-amino-3-chlorobenzoate is 7 μg/m3 based on an annual averaging time.

References

[1] Patent: US2006/94707, 2006, A1. Location in patent: Page/Page column 64
[2] Patent: US2007/259850, 2007, A1. Location in patent: Page/Page column 99
[3] Bioorganic and Medicinal Chemistry, 1999, vol. 7, # 8, p. 1743 - 1754

Methyl 2-amino-3-chlorobenzoate Preparation Products And Raw materials

Raw materials

Preparation Products

Less

Methyl 2-amino-3-chlorobenzoate Suppliers

Americas 1 China 188 Europe 3 France 1 Germany 2 India 4 Japan 1 Ukraine 1 United Kingdom 10 United States 23 Global 234

Shanghai Kaisai Chemical Co., Ltd

Tel: 021-33516722 13701817765
Fax: 021-33516776
Email: kaisaichem@163.com
Country: China
ProdList: 4610
Advantage: 58

MedicalChem(Yancheng)Manuf.Co.,Ltd

Tel: +86-515-84383180
Fax: +86-515-84383182
Email: sales@medicalchem.com
Country: China
ProdList: 80
Advantage: 69

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

TAIYUAN RHF CO.,LTD.

Tel: +86 351 7031519
Fax: +86 351 7031519
Email: sales@RHFChem.com
Country: China
ProdList: 2338
Advantage: 56

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 2807
Advantage: 65

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

Shangchem Co., Ltd.

Tel: +86-21-68182121
Fax: +86-21-68182121
Country: China
ProdList: 882
Advantage: 52

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Shanghai Harvest Chemical Industrial Co., Ltd.

Tel: 021-31038972,31038973 17321035817
Fax: +86-21-51385350
Email: sales@harvest-chem.com
Country: China
ProdList: 2816
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Shanghai Ennopharm Co., Ltd.

Tel: +86 (21) 6435-5022
Country: China
ProdList: 4267
Advantage: 65

skychemical Co.Ltd

Tel: 021-20958197 20965099
Fax: 021-20960837
Email: sales@skychemical.com
Country: China
ProdList: 1183
Advantage: 57

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 6387
Advantage: 52

Wuhan Haizheng Industry & Trade Development Co. Ltd

Tel: 027-8866 0053/88660577/88660578
Fax: 027-8899 1911
Country: China
ProdList: 1073
Advantage: 55

Shanghai Topbiochem Technology Co., Ltd

Tel: +86-21-60341587
Fax: +86-21-61294319
Email: sales@topbiochem.com
Country: China
ProdList: 6175
Advantage: 58

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9546
Advantage: 55

Chem-Stone Co.,Ltd.

Tel: 020-82185713,82185709 13418171485
Fax: 020-82185696
Email: sales@chem-stone.com
Country: China
ProdList: 744
Advantage: 56

Aloespharm Co., Ltd.

Tel: 021-20960837
Fax: 021-20960837
Email: market@aloespharm.com
Country: China
ProdList: 1302
Advantage: 55

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9979
Advantage: 55

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Country: China
ProdList: 2930
Advantage: 58

Tianjin Anhao Biological Technology Co., Ltd.

Tel
Email: sales@ahpharmatech.com
Country: China
ProdList: 5734
Advantage: 55

SHANGHAI BANGCHENG CHEMICAL Co.,Ltd.

Tel: 021-69106960 13701823733
Fax: 021-69106780
Email: 13701823733@163.com
Country: China
ProdList: 4641
Advantage: 60

Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9793
Advantage: 50

Shanghai Yongye Biotechnology Co., Ltd.

Tel: 86-021-61559134 15921386130
Fax: 021-55068248
Email: 3423497944@qq.com
Country: China
ProdList: 8144
Advantage: 55

Shanghai Synteam Biochem CO.,ltd

Tel: +86-021-58380978 13482386415
Fax: 021-58380978
Email: info@systeambc.com
Country: China
ProdList: 896
Advantage: 50

Beijing Xinsavi Chemical Technology Co., Ltd.

Tel: 010-56218822 13717722232
Fax: 010-56218800
Email: xinsavichem@163.com
Country: China
ProdList: 3201
Advantage: 56

Beijing Holiyang Chemical Co. Ltd.

Tel: 13718199399
Fax: QQ : 206661479
Email: holiyangchem@163.com
Country: China
ProdList: 3280
Advantage: 56

Shanghai YouPeng Chemical Co. Ltd.

Tel: 021-69005955 13701776567
Fax: 021-69005775
Email: youpengchem@163.com
Country: China
ProdList: 4161
Advantage: 56

Sichuan Hainuowei Technology Co. Ltd.

Tel: 13708085536 13708085536
Fax: QQ : 121102042
Email: hanovichem@163.com
Country: China
ProdList: 3282
Advantage: 56

Shanghai TongYuan Chemical Co., Ltd.

Tel: 021-021-69182866 13701855675
Fax: 021-69182022
Email: tongyuanchem@126.com
Country: China
ProdList: 4193
Advantage: 58

Beijing HuaYangZhicheng Technology Co., Ltd.

Tel: 13716033033
Fax: 010-56276266
Email: hanchochem@163.com
Country: China
ProdList: 2960
Advantage: 50

Shanghai LanRun Chemical Co., Ltd.

Tel: 021-69515658 ; 69515628 13701998368
Fax: 021-69515998
Email: longrunchem@163.com
Country: China
ProdList: 3786
Advantage: 50

Shanghai Rolead Chemical Technology Co., Ltd.

Tel: 021-69992220 13701886816
Fax: 021-69992237
Email: roleadchem@163.com
Country: China
ProdList: 4613
Advantage: 50

Shanghai Kangtuo Chemical Co., Ltd.

Tel: 021-69185552 13701777608
Fax: 021-69186006
Email: kangtuochem@163.com
Country: China
ProdList: 4232
Advantage: 55

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

Hubei Jusheng Technology Co.,Ltd

Tel: 027-59599241 18871490274
Fax: 027-59599241
Email: 1400878000@qq.com
Country: China
ProdList: 9858
Advantage: 58

Jiangsu Mingchem Corporation

Tel: 0519-85170101
Fax: 0519-85170505
Email: sales@mingchem.com
Country: China
ProdList: 608
Advantage: 55

Changzhou Anxuan Chemical, Co., Ltd.

Tel: 13912302692 13912302692;
Fax: 0519-88064678
Email: sales@anxuanchem.com
Country: China
ProdList: 4828
Advantage: 58

Chengdu Research Accelerators Technology Co., Ltd.

Tel: 028-64353063
Fax: 028-64353063 QQ:784253935
Email: reacchemical@163.com
Country: China
ProdList: 5253
Advantage: 58

Chengdu JingXin Technology Co., Ltd.

Tel: 028-85005297 13980656781
Fax: 028-85005529
Email: jingxin73730@163.com
Country: China
ProdList: 3280
Advantage: 50

skychemical Co.Ltd

Tel: 021-20960837,QQ1332204249
Fax: 021-20960837
Email: sales@skychemical.com
Country: China
ProdList: 3341
Advantage: 55

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Email: sales@chemwill.com
Country: China
ProdList: 1974
Advantage: 58

ShangHai Siyan Biological Technology Co., Ltd.

Tel: 021-50908862，442785678，326799392 18721037013
Fax: 021-50908862
Email: siyansales@126.com
Country: China
ProdList: 9627
Advantage: 58

Shanghai Haozhixiang Biotechnology Co., Ltd

Tel: 526763801 13301653310
Fax: +86-21-51619052
Email: 526763801@qq.com
Country: China
ProdList: 9274
Advantage: 55

Henan CoreyChem Co., Ltd

Tel: 0371-86658258
Fax: 0371-60996044
Email: info@coreychem.com
Country: China
ProdList: 10453
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shanghai XiZhi Chemical Co., Ltd.

Tel: 021-69005855 13701817869
Fax: 021-69005955
Email: xizhichem@163.com
Country: China
ProdList: 3339
Advantage: 55

Less

View Lastest Price from Methyl 2-amino-3-chlorobenzoate manufacturers

HANGZHOU HAILAN CHEMICAL CO.,LTD.

Product: Methyl 2-amino-3-chlorobenzoate 77820-58-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 20tons
Release date: 2025-08-21

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: Methyl 2-amino-3-chlorobenzoate 77820-58-7
Price: US $3.00-9.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2025-06-21

Qingdao RENAS Polymer Material Co., Ltd.

Product: 2-Amino-3-Chlorobenzoic Acid Methyl Ester 77820-58-7
Price: US $0.00/kg
Min. Order: 20kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2024-08-26

77820-58-7, Methyl 2-amino-3-chlorobenzoateRelated Search:

Basic Violet 1 Methyl 2-bromobenzoate Methyl salicylate Glycine Methyl formate Tribenuron methyl Methylparaben Methyl acrylate Methyl benzoate Methyl carbamate Methyl anthranilate Kresoxim-methyl Methanol METSULFURON METHYL Methyl (2-amino-5-bromo-3-chlorophenyl)methanol Ambroxol Imp.O Ambroxol Impurity 19

2-AMINO-3-CHLORO-BENZOIC ACID METHYL ESTER

METHYL 3-CHLORO-2-AMINOBENZOATE

METHYL 2-AMINO-3-CHLOROBENZOATE

2-amino-3-chlorobenzate ester

2-Amino-3-ChlorobenzonicAcidMethylEster

2-Amino-3-chlorbenzoesuremethylester

3-CHLOROANTHRANILIC ACID, METHYL ESTER

Benzoic acid, 2-amino-3-chloro-, methyl ester

Methyl 3-chloroanthranilate

3-Chloroanthranilic acid methyl ester (COOCH3=1)

2-amino-3-chloroben

77820-58-7

820-58-7

C8H8CINO2

Aromatic Esters

Organic acids

FINE Chemical & INTERMEDIATES

K00001