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Trimetazidine N-oxide

Product Name
Trimetazidine N-oxide
CAS No.
1644530-89-1
Chemical Name
Trimetazidine N-oxide
Synonyms
Trimetazidine N-oxide;Trimetazidine N-Oxide HCl;Piperazine, 1-hydroxy-4-[(2,3,4-trimethoxyphenyl)methyl]-;Trimetazidine N-Oxide DiHCl/1-(2,3,4-Trimethoxybenzyl)piperazine 1-oxide dihydrochloride
CBNumber
CB93313180
Molecular Formula
C14H22N2O4
Formula Weight
282.34
MOL File
1644530-89-1.mol
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Trimetazidine N-oxide Property

Boiling point:
397.1±42.0 °C(Predicted)
Density 
1.196±0.06 g/cm3(Predicted)
pka
13.23±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

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Trimetazidine N-oxide Chemical Properties,Usage,Production

Uses

Trimetazidine-N-oxide is the major active metabolite of Trimetazidine. Trimetazidine is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM. Trimetazidine is an effective antianginal agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties.

References

[1] Sigmund G, et al. Doping control analysis of trimetazidine and characterization of major metabolites using mass spectrometric approaches. Drug Test Anal. 2014 Nov-Dec;6(11-12):1197-205. DOI:10.1002/dta.1680

Trimetazidine N-oxide Preparation Products And Raw materials

Raw materials

Preparation Products

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Trimetazidine N-oxide Suppliers

XinYao(Shenzhen) Biological Technology Co., Ltd.
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0755-89880280
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0755-89880280
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3004662104@qq.com
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China
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TargetMol Chemicals Inc.
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+1-781-999-5354; +17819995354
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marketing@targetmol.com
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United States
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Shanghai Botuo Biotechnology Co., LTD
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16621358918
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QQ:402135374
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botuopharma888@163.com
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China
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Guangzhou Juntang Technology Co., Ltd
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020-36607679 13502246435
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sales@dmstandards.com
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China
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10945
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RD International Technology Co., Limited
Tel
18024082417
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market@ubiochem.com
Country
China
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9835
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TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
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29247
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China National Standard Pharmaceutical Corporation Limited
Tel
+8615391658522
Email
overseasales@yongstandards.com
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China
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11922
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