ChemicalBook > CAS DataBase List > Trimetazidine N-oxide
Trimetazidine N-oxide
- Product Name
- Trimetazidine N-oxide
- CAS No.
- 1644530-89-1
- Chemical Name
- Trimetazidine N-oxide
- Synonyms
- Trimetazidine N-oxide;Trimetazidine N-Oxide HCl;Piperazine, 1-hydroxy-4-[(2,3,4-trimethoxyphenyl)methyl]-;Trimetazidine N-Oxide DiHCl/1-(2,3,4-Trimethoxybenzyl)piperazine 1-oxide dihydrochloride
- CBNumber
- CB93313180
- Molecular Formula
- C14H22N2O4
- Formula Weight
- 282.34
- MOL File
- 1644530-89-1.mol
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Trimetazidine N-oxide Property
- Boiling point:
- 397.1±42.0 °C(Predicted)
- Density
- 1.196±0.06 g/cm3(Predicted)
- pka
- 13.23±0.20(Predicted)
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Trimetazidine N-oxide Chemical Properties,Usage,Production
Uses
Trimetazidine-N-oxide is the major active metabolite of Trimetazidine. Trimetazidine is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM. Trimetazidine is an effective antianginal agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties.
References
[1] Sigmund G, et al. Doping control analysis of trimetazidine and characterization of major metabolites using mass spectrometric approaches. Drug Test Anal. 2014 Nov-Dec;6(11-12):1197-205. DOI:10.1002/dta.1680
Trimetazidine N-oxide Preparation Products And Raw materials
Raw materials
Preparation Products
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1644530-89-1, Trimetazidine N-oxideRelated Search:
2,3,4-Trimethoxybenzoic acid
Piperazine
4-DesMethoxy-4-broMo TriMethopriM
beta-(dimethylamino)-beta-ethylphenethyl alcohol
2-amino-5-[(3,4,5-trimethoxyphenyl)methyl]-1H-pyrimidin-4-one
2,4,6-TRIMETHOXYPHENYLACETIC ACID
1-[(2,4,6-TriMethoxyphenyl)Methyl]piperazine Hydrochloride
3-Iodobenzylamine hydrochloride
N-Methyl Trimetazidine Dihydrochloride
1-(3,4,5-TRIMETHOXY-BENZYL)-PIPERAZINE
1-Dimethylamino-2-phenylbutan-2-yl 3,4,5-trimethoxybenzoate
4-[(2,3,4-TriMethoxyphenyl)Methyl]-1-piperazinecarboxylic Acid Ethyl Ester
1,4-Bis(2,3,4-triMethoxybenzyl)piperazine
Trimethoprim Related Compound B (25 mg) (2,4-diaminopyrimidin-5-yl)(3,4,5-trimethoxyphenyl)methanone) (AS)
3-Anilino-2-(3,4,5-triMethoxybenzyl)acrylonitrile, (Mixture of cis/trans isoMers)
2,3,4-Trihydroxybenzaldehyde
3-Iodobenzyl bromide
TriMethopriM IMpurity C