2,3,4-Trihydroxybenzaldehyde

Product Name: 2,3,4-Trihydroxybenzaldehyde
CAS No.: 2144-08-3
Chemical Name: 2,3,4-Trihydroxybenzaldehyde
Synonyms: 2,3,4-Trihydroxybenazldehyde;2,3,4-THB;NSC 22595;PYROGALLOLALDEHYDE;2,3,4-TrihydroxybenzaL;Pyrogallolcarboxaldehyde;,3,4-Trihydroxybenzaldehyd;PYROGALLOL-4-CARBOXALDEHYDE;2,3,4-Trihdroxybenzaldehyde;2,3,4-TRIHYDROXYBENZALDEHYDE
CBNumber: CB1396755
Molecular Formula: C7H6O4
Formula Weight: 154.12
MOL File: 2144-08-3.mol

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2,3,4-Trihydroxybenzaldehyde Property

Melting point:: 159-161 °C (lit.)
Boiling point:: 237.46°C (rough estimate)
Density: 1.3725 (rough estimate)
refractive index: 1.6400 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: DMSO, Methanol
form: Powder
pka: 7.41±0.23(Predicted)
color: Light brown to beige-brown
Water Solubility: 1.541g/L at 25℃
Sensitive: Air Sensitive
BRN: 2328658
LogP: 1.25
CAS DataBase Reference: 2144-08-3(CAS DataBase Reference)
EPA Substance Registry System: Benzaldehyde, 2,3,4-trihydroxy- (2144-08-3)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39-36
WGK Germany: 2
RTECS: CU8439800
TSCA: Yes
HS Code: 29124990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 260843
Product name: 2,3,4-Trihydroxybenzaldehyde
Purity: 98%
Packaging: 5g
Price: $67.2
Updated: 2024/03/01

TCI Chemical

Product number: T2158
Product name: 2,3,4-Trihydroxybenzaldehyde
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $30
Updated: 2024/03/01

TCI Chemical

Product number: T2158
Product name: 2,3,4-Trihydroxybenzaldehyde
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $87
Updated: 2024/03/01

Alfa Aesar

Product number: A13745
Product name: 2,3,4-Trihydroxybenzaldehyde, 98%
Packaging: 5g
Price: $42.65
Updated: 2024/03/01

Alfa Aesar

Product number: A13745
Product name: 2,3,4-Trihydroxybenzaldehyde, 98%
Packaging: 25g
Price: $177
Updated: 2024/03/01

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2,3,4-Trihydroxybenzaldehyde Chemical Properties,Usage,Production

Description

2,3, 4-trihydroxybenzaldehyde is an essential intermediate of the antiparkinson drug benserazide, which is a peripheral dopa decarboxylase inhibitor, usually benserazide: the L-dopa is prepared into a compound preparation at a ratio of 1:4, and has a remarkable effect of treating the Parkinson's disease.

Chemical Properties

light brown to beige-brown powder

Uses

2,3,4-Trihydroxybenzaldehyde is a phenolic benzaldehyde with antibacterial activity.

Uses

2,3,4-Trihydroxybenzaldehyde has been used in the preparation of 1,5-dimethyl-2-phenyl-4-[(1E)-(2,3,4-trihydroxybenzylidene)amino]-1H-pyrazol-3(2H)-one.

General Description

Antimicrobial activity of carbohydrazone derived from 2,3,4-trihydroxybenzaldehyde against bacteria and fungi has been investigated. 2,3,4-trihydroxybenzaldehyde forms Schiff bases via [1+1] condensation with anthranilic acid.

Synthesis

The method for synthesizing 2,3, 4-trihydroxybenzaldehyde is shown as follows.
This method takes pyrogallol as an initial raw material. It comprises three steps of phenolic hydroxyl protection, formylation, and deprotection: protecting two adjacent phenolic hydroxyl groups in the pyrogallol to obtain 4-hydroxybenzo[d][1,3]dioxol-2-one, then performing formylation to obtain 7-hydroxy-2-oxobenzo[d][1,3]dioxole-4-carbaldehyde, and finally removing a protecting group to get a target 2,3,4-trihydroxybenzaldehyde.

2,3,4-Trihydroxybenzaldehyde Preparation Products And Raw materials

Raw materials

Gallic acid

Preparation Products

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2,3,4-Trihydroxybenzaldehyde Suppliers

Belgium 1 Canada 2 China 325 Europe 2 France 1 Germany 5 India 8 Japan 3 Slovakia 1 South Korea 1 Switzerland 2 The Netherlands 1 United Kingdom 11 United States 32 Global 395

HSDK（Nanjing）Pharma Tech Co.，Ltd.

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Alfa Aesar

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View Lastest Price from 2,3,4-Trihydroxybenzaldehyde manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 2,3,4-Trihydroxybenzaldehyde 2144-08-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99.5%min
Supply Ability: 2000kg
Release date: 2022-11-24

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

Product: 2,3,4-Trihydroxybenzaldehyde 2144-08-3
Price: US $990.00-800.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000
Release date: 2024-08-19

Hebei Weibang Biotechnology Co., Ltd

Product: 2,3,4-Trihydroxybenzaldehyde 2144-08-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-31

2144-08-3, 2,3,4-TrihydroxybenzaldehydeRelated Search:

Protocatechualdehyde Salicylaldehyde Benzaldehyde 3-Hydroxybenzaldehyde 2,3,4-Trimethoxybenzaldehyde 4-Hydroxybenzaldehyde 2-(Trifluoromethyl)benzaldehyde 3-(Trifluoromethyl)benzaldehyde 2,3-Dihydroxybenzaldehyde p-Anisaldehyde 2,3,4-TRIMETHOXYPHENYLACETIC ACID TriMethopriM IMpurity C 3-Iodobenzyl bromide 3-Anilino-2-(3,4,5-triMethoxybenzyl)acrylonitrile, (Mixture of cis/trans isoMers) Trimethoprim Related Compound B (25 mg) (2,4-diaminopyrimidin-5-yl)(3,4,5-trimethoxyphenyl)methanone) (AS) 1,4-Bis(2,3,4-triMethoxybenzyl)piperazine 4-[(2,3,4-TriMethoxyphenyl)Methyl]-1-piperazinecarboxylic Acid Ethyl Ester 1-(3,4,5-TRIMETHOXY-BENZYL)-PIPERAZINE

2,3,4-TrihydroxybenzaL

2,3,4-TRIHYDROXYBENZALDEHYDE

2,3,4-Trihydroxybenzaldehyde,98%

2,3,4-TRIHYDROXYBENZALDEHYDE 98%

PYROGALLOLALDEHYDE

PYROGALLOL-4-CARBOXALDEHYDE

2,3,4-Trihydroxybenazldehyde

2,3,4-THB

Pyrogallolcarboxaldehyde

2,3,4-Trihydroxybenzaldehyde,Pyrogallol-4-carboxaldehyde

2,3,4-Trihydroxybenzaldehyde, 98% 5GR

3,4-Dihydroxysalicylaldehyde

NSC 22595

Benzaldehyde,2,3,4-trihydroxy-

2,3,4-Trihdroxybenzaldehyde

2,3,4-Trihydroxybenzaldehyde ISO 9001：2015 REACH

TIANFU-CHEM - 2,3,4-Trihydroxybenzaldehyde

,3,4-Trihydroxybenzaldehyd

2144-08-3

2144-04-3

89-33-6

2144-8-3

2144-06-3

2144-08-03

C7H6O4

ALDEHYDE

Organic Building Blocks

Aldehydes

Building Blocks

Carbonyl Compounds

C7

Aromatic Aldehydes & Derivatives (substituted)

Benzaldehyde

2144-08-3