ChemicalBook > CAS DataBase List > 2,3,4-Trihydroxybenzaldehyde

2,3,4-Trihydroxybenzaldehyde

Product Name
2,3,4-Trihydroxybenzaldehyde
CAS No.
2144-08-3
Chemical Name
2,3,4-Trihydroxybenzaldehyde
Synonyms
2,3,4-Trihydroxybenazldehyde;2,3,4-THB;NSC 22595;PYROGALLOLALDEHYDE;2,3,4-TrihydroxybenzaL;Pyrogallolcarboxaldehyde;,3,4-Trihydroxybenzaldehyd;PYROGALLOL-4-CARBOXALDEHYDE;2,3,4-Trihdroxybenzaldehyde;2,3,4-TRIHYDROXYBENZALDEHYDE
CBNumber
CB1396755
Molecular Formula
C7H6O4
Formula Weight
154.12
MOL File
2144-08-3.mol
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2,3,4-Trihydroxybenzaldehyde Property

Melting point:
159-161 °C (lit.)
Boiling point:
237.46°C (rough estimate)
Density 
1.3725 (rough estimate)
refractive index 
1.6400 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO, Methanol
form 
Powder
pka
7.41±0.23(Predicted)
color 
Light brown to beige-brown
Water Solubility 
1.541g/L at 25℃
Sensitive 
Air Sensitive
BRN 
2328658
LogP
1.25
CAS DataBase Reference
2144-08-3(CAS DataBase Reference)
EPA Substance Registry System
Benzaldehyde, 2,3,4-trihydroxy- (2144-08-3)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-36
WGK Germany 
2
RTECS 
CU8439800
TSCA 
Yes
HS Code 
29124990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
260843
Product name
2,3,4-Trihydroxybenzaldehyde
Purity
98%
Packaging
5g
Price
$67.2
Updated
2024/03/01
TCI Chemical
Product number
T2158
Product name
2,3,4-Trihydroxybenzaldehyde
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$30
Updated
2024/03/01
TCI Chemical
Product number
T2158
Product name
2,3,4-Trihydroxybenzaldehyde
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$87
Updated
2024/03/01
Alfa Aesar
Product number
A13745
Product name
2,3,4-Trihydroxybenzaldehyde, 98%
Packaging
5g
Price
$42.65
Updated
2024/03/01
Alfa Aesar
Product number
A13745
Product name
2,3,4-Trihydroxybenzaldehyde, 98%
Packaging
25g
Price
$177
Updated
2024/03/01
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2,3,4-Trihydroxybenzaldehyde Chemical Properties,Usage,Production

Description

2,3, 4-trihydroxybenzaldehyde is an essential intermediate of the antiparkinson drug benserazide, which is a peripheral dopa decarboxylase inhibitor, usually benserazide: the L-dopa is prepared into a compound preparation at a ratio of 1:4, and has a remarkable effect of treating the Parkinson's disease.

Chemical Properties

light brown to beige-brown powder

Uses

2,3,4-Trihydroxybenzaldehyde is a phenolic benzaldehyde with antibacterial activity.

Uses

2,3,4-Trihydroxybenzaldehyde has been used in the preparation of 1,5-dimethyl-2-phenyl-4-[(1E)-(2,3,4-trihydroxybenzylidene)amino]-1H-pyrazol-3(2H)-one.

General Description

Antimicrobial activity of carbohydrazone derived from 2,3,4-trihydroxybenzaldehyde against bacteria and fungi has been investigated. 2,3,4-trihydroxybenzaldehyde forms Schiff bases via [1+1] condensation with anthranilic acid.

Synthesis

The method for synthesizing 2,3, 4-trihydroxybenzaldehyde is shown as follows.
This method takes pyrogallol as an initial raw material. It comprises three steps of phenolic hydroxyl protection, formylation, and deprotection: protecting two adjacent phenolic hydroxyl groups in the pyrogallol to obtain 4-hydroxybenzo[d][1,3]dioxol-2-one, then performing formylation to obtain 7-hydroxy-2-oxobenzo[d][1,3]dioxole-4-carbaldehyde, and finally removing a protecting group to get a target 2,3,4-trihydroxybenzaldehyde.

2,3,4-Trihydroxybenzaldehyde Preparation Products And Raw materials

Raw materials

Gallic acid

Preparation Products

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2,3,4-Trihydroxybenzaldehyde Suppliers

Belgium 1 Canada 2 China 329 Europe 2 France 1 Germany 5 India 8 Japan 3 Slovakia 1 South Korea 1 Switzerland 2 The Netherlands 1 United Kingdom 11 United States 33 Global 400
ecochem international chemical broker
Tel
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Fax
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Email
export@ecochem.dk
Country
Europe
ProdList
6371
Advantage
66
kemikalieimport
Tel
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Fax
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Email
Sales@kemikalieimport.dk
Country
Europe
ProdList
6685
Advantage
47
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View Lastest Price from 2,3,4-Trihydroxybenzaldehyde manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
2,3,4-Trihydroxybenzaldehyde 2144-08-3
Price
US $0.00/kg
Min. Order
1kg
Purity
99.5%min
Supply Ability
2000kg
Release date
2022-11-24
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
2,3,4-Trihydroxybenzaldehyde 2144-08-3
Price
US $990.00-800.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-19
Hebei Weibang Biotechnology Co., Ltd
Product
2,3,4-Trihydroxybenzaldehyde 2144-08-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-31

2144-08-3, 2,3,4-TrihydroxybenzaldehydeRelated Search:

Protocatechualdehyde Salicylaldehyde Benzaldehyde 3-Hydroxybenzaldehyde 2,3,4-Trimethoxybenzaldehyde 4-Hydroxybenzaldehyde 2-(Trifluoromethyl)benzaldehyde 3-(Trifluoromethyl)benzaldehyde 2,3-Dihydroxybenzaldehyde p-Anisaldehyde 2,3,4-TRIMETHOXYPHENYLACETIC ACID TriMethopriM IMpurity C 3-Iodobenzyl bromide 3-Anilino-2-(3,4,5-triMethoxybenzyl)acrylonitrile, (Mixture of cis/trans isoMers) Trimethoprim Related Compound B (25 mg) (2,4-diaminopyrimidin-5-yl)(3,4,5-trimethoxyphenyl)methanone) (AS) 1,4-Bis(2,3,4-triMethoxybenzyl)piperazine 4-[(2,3,4-TriMethoxyphenyl)Methyl]-1-piperazinecarboxylic Acid Ethyl Ester 1-(3,4,5-TRIMETHOXY-BENZYL)-PIPERAZINE

  • 2,3,4-TrihydroxybenzaL
  • 2,3,4-TRIHYDROXYBENZALDEHYDE
  • 2,3,4-Trihydroxybenzaldehyde,98%
  • 2,3,4-TRIHYDROXYBENZALDEHYDE 98%
  • PYROGALLOLALDEHYDE
  • PYROGALLOL-4-CARBOXALDEHYDE
  • 2,3,4-Trihydroxybenazldehyde
  • 2,3,4-THB
  • Pyrogallolcarboxaldehyde
  • 2,3,4-Trihydroxybenzaldehyde,Pyrogallol-4-carboxaldehyde
  • 2,3,4-Trihydroxybenzaldehyde, 98% 5GR
  • 3,4-Dihydroxysalicylaldehyde
  • NSC 22595
  • Benzaldehyde,2,3,4-trihydroxy-
  • 2,3,4-Trihdroxybenzaldehyde
  • 2,3,4-Trihydroxybenzaldehyde ISO 9001：2015 REACH
  • TIANFU-CHEM - 2,3,4-Trihydroxybenzaldehyde
  • ,3,4-Trihydroxybenzaldehyd
  • 2144-08-3
  • 2144-04-3
  • 89-33-6
  • 2144-8-3
  • 2144-06-3
  • 2144-08-03
  • C7H6O4
  • ALDEHYDE
  • Organic Building Blocks
  • Aldehydes
  • Building Blocks
  • Carbonyl Compounds
  • C7
  • Aromatic Aldehydes & Derivatives (substituted)
  • Benzaldehyde
  • 2144-08-3