ChemicalBook > CAS DataBase List > 2,3,4-Trimethoxybenzaldehyde

2,3,4-Trimethoxybenzaldehyde

Product Name
2,3,4-Trimethoxybenzaldehyde
CAS No.
2103-57-3
Chemical Name
2,3,4-Trimethoxybenzaldehyde
Synonyms
TriMetazidine EP IMpurity-C;Benzaldehyde, 2,3,4-trimethoxy-;2,3,4-TMB;AKOS BBS-00003174;2,3,4-TrimethoxybenzaL;Trimetazidine Impurity C;4-TriMethoxybenzaldehyde;trimetazidine impurity1139;2,3,4-Trimetoxybenzaldehyde;Trimetazidine intermediate
CBNumber
CB9260504
Molecular Formula
C10H12O4
Formula Weight
196.2
MOL File
2103-57-3.mol
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2,3,4-Trimethoxybenzaldehyde Property

Melting point:
38-40 °C(lit.)
Boiling point:
168-170 °C12 mm Hg(lit.)
Density 
1.2166 (rough estimate)
refractive index 
n20/D 1.5547(lit.)
Flash point:
>230 °F
storage temp. 
Inert atmosphere,2-8°C
solubility 
methanol: 0.1 g/mL, clear
form 
Crystals or Crystalline Powder
color 
White to light yellow
Sensitive 
Air Sensitive
BRN 
981091
InChI
InChI=1S/C10H12O4/c1-12-8-5-4-7(6-11)9(13-2)10(8)14-3/h4-6H,1-3H3
InChIKey
UCTUXUGXIFRVGX-UHFFFAOYSA-N
SMILES
C(=O)C1=CC=C(OC)C(OC)=C1OC
CAS DataBase Reference
2103-57-3(CAS DataBase Reference)
NIST Chemistry Reference
Benzaldehyde, 2,3,4-trimethoxy-(2103-57-3)
EPA Substance Registry System
Benzaldehyde, 2,3,4-trimethoxy- (2103-57-3)
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Safety

Hazard Codes 
Xi,C
Risk Statements 
36/37/38-34
Safety Statements 
22-24/25-45-36/37/39-27-26
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29124900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
152099
Product name
2,3,4-Trimethoxybenzaldehyde
Purity
99%
Packaging
10g
Price
$33.3
Updated
2024/03/01
Sigma-Aldrich
Product number
152099
Product name
2,3,4-Trimethoxybenzaldehyde
Purity
99%
Packaging
50g
Price
$108
Updated
2024/03/01
TCI Chemical
Product number
T1101
Product name
2,3,4-Trimethoxybenzaldehyde
Purity
>98.0%(GC)
Packaging
25g
Price
$66
Updated
2024/03/01
Alfa Aesar
Product number
A10609
Product name
2,3,4-Trimethoxybenzaldehyde, 98+%
Packaging
10g
Price
$28.65
Updated
2024/03/01
Alfa Aesar
Product number
A10609
Product name
2,3,4-Trimethoxybenzaldehyde, 98+%
Packaging
50g
Price
$102.65
Updated
2024/03/01
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2,3,4-Trimethoxybenzaldehyde Chemical Properties,Usage,Production

Description

2,3,4-Trimethoxybenzaldehyde is a white crystalline powder, and the chemical formula is C 10H 12O 4; the molecular weight is 196.2; the fusing point is 38-40 degrees, and is a kind of important medicine intermediate; it is mainly used in new type drug Ca2+ Synthesizing of channel blocker. The alternative cerebral arteries that are used for this medicine reduce the headache incidence, mainly for the preparation of the intermediate of trimetazidine.

Synthesis

A coking gallic acid is utilized as a raw material, and dimethyl sulfate is utilized as an alkylate reagent; under the condition of the existence of sodium hydroxide, methylation is performed through an O-alkylation reaction to obtain an intermediate 1, 2, 3-trimethoxybenzene. After that, the 1,2, 3-trimethoxybenzene and a Vilsmeier-Haack reagent are subjected to a formylation reaction to get the 2,3,4-Trimethoxybenzaldehyde.

Chemical Properties

white to light yellow crystals or cryst. powder

Uses

2,3,4-Trimethoxybenzaldehyde is a trimethoxylated aromatic aldehyde. 2,3,4-Trimethoxybenzaldehyde is an Impurity of the anti-anginal drug Trimetazidine (T795610).

Uses

2,3,4-Trimethoxybenzaldehyde was used to study the effects of 2,3,4-trimethoxybenzaldehyde on tubulin-dependent GTP hydrolysis.

2,3,4-Trimethoxybenzaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3,4-Trimethoxybenzaldehyde Suppliers

Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
Shanghai changwei industrial development co., LTD
Tel
13262956501
Email
cli@sunwayshanghai.com
Country
China
ProdList
298
Advantage
58
Shanghai Zhen Li Biological Technology Co., Ltd
Tel
021-16621358918; 18516310516
Fax
13045646768
Email
zhenlipharma888@163.com
Country
China
ProdList
1978
Advantage
58
WUFENG CHICHENG BIOTECH CO LTD
Tel
0717-5757168 13997700995
Email
wfcchem@126.com
Country
China
ProdList
15
Advantage
58
Beijing Wisdom Chemicals Co., Ltd.
Tel
010-59777827 13701052487
Email
sales1@wisdomchem.com
Country
China
ProdList
241
Advantage
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J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2341
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
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View Lastest Price from 2,3,4-Trimethoxybenzaldehyde manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
2,3,4-Trimethoxybenzaldehyde 2103-57-3
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000kg
Release date
2024-03-20
Hebei Dangtong Import and export Co LTD
Product
2,3,4-Trimethoxybenzaldehyde 2103-57-3
Price
US $86.00-76.00/kg
Min. Order
10kg
Purity
99.99%
Supply Ability
100Tons
Release date
2023-03-02
Zibo Hangyu Biotechnology Development Co., Ltd
Product
2,3,4-Trimethoxybenzaldehyde 2103-57-3
Price
US $80.00-800.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-10-31

2103-57-3, 2,3,4-TrimethoxybenzaldehydeRelated Search:


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  • 2103-57-3
  • 2103-57-31
  • Organic Building Blocks
  • ALDEHYDE
  • Aldehydes
  • Building Blocks
  • C10 to C21
  • Carbonyl Compounds
  • Aromatics, Impurities, Intermediates
  • BUILDING BLOCKS
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  • bc0001
  • 2103-57-3