3,5-BIS(4-NITROPHENOXY)BENZOIC ACID

Product Name: 3,5-BIS(4-NITROPHENOXY)BENZOIC ACID
CAS No.: 173550-33-9
Chemical Name: 3,5-BIS(4-NITROPHENOXY)BENZOIC ACID
Synonyms: NSC400980;NSC 400980;NSC-400980;3,5-BIS(4-NITROPHENOXY)BENZOIC ACID;Benzoic acid, 3,5-bis(4-nitrophenoxy)-;3,5-Bis(4-nitrophenoxy)benzoic Acid >3,5-BIS(4-NITROPHENOXY)BENZOIC ACID 98+%
CBNumber: CB9332982
Molecular Formula: C19H12N2O8
Formula Weight: 396.31
MOL File: 173550-33-9.mol

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3,5-BIS(4-NITROPHENOXY)BENZOIC ACID Property

Melting point:: 229.0 to 233.0 °C
Boiling point:: 577.7±50.0 °C(Predicted)
Density: 1.485±0.06 g/cm3(Predicted)
storage temp.: Store at +4°C
solubility: almost transparency in hot DMF
form: powder to crystal
pka: 3.63±0.10(Predicted)
color: Light orange to Yellow to Green

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Safety

HS Code: 2918.99.4700

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical

Product number: B2120
Product name: 3,5-Bis(4-nitrophenoxy)benzoic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $280
Updated: 2025/07/31

TRC

Product number: C643513
Product name: CompoundW
Packaging: 250mg
Price: $105
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB61753
Product name: 3,5-Bis(4-nitrophenoxy)benzoic Acid
Packaging: 500mg
Price: $40
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB61753
Product name: 3,5-Bis(4-nitrophenoxy)benzoic Acid
Packaging: 1g
Price: $67
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB61753
Product name: 3,5-Bis(4-nitrophenoxy)benzoic Acid
Packaging: 2g
Price: $116
Updated: 2021/12/16

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3,5-BIS(4-NITROPHENOXY)BENZOIC ACID Chemical Properties,Usage,Production

Uses

3,5-Bis(4-nitrophenoxy)benzoic acid is an inhibitor of γ-secretase. 3,5-Bis(4-nitrophenoxy)benzoic acid causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25). 3,5-Bis(4-nitrophenoxy)benzoic acid, as a marker for fetal hypothyroidism, is a 3,3’-diiodothyronine sulfate (T2S) cross-reactive material in maternal serum[1].

Definition

ChEBI: 3,5-bis(4-nitrophenoxy)benzoic acid is an aromatic ether.

Biological Activity

Inhibitor of γ -secretase; causes a decrease in the released levels of A β 42 and notch-1 A β -like peptide 25 (N β 25).

References

[1] Wu SY, et al. Compound W, a 3,3'-diiodothyronine sulfate cross-reactive substance in serum from pregnant women--a potential marker for fetal thyroid function. Pediatr Res. 2007;61(3):307-312. DOI:10.1203/pdr.0b013e318030d17d
[2] Ran Y, et al. Differential Inhibition of Signal Peptide Peptidase Family Members by Established γ-Secretase Inhibitors. PLoS One. 2015;10(6):e0128619. Published 2015 Jun 5. DOI:10.1371/journal.pone.0128619
[3] Greife A, et al. Canonical Notch signalling is inactive in urothelial carcinoma. BMC Cancer. 2014;14:628. Published 2014 Aug 29. DOI:10.1186/1471-2407-14-628

3,5-BIS(4-NITROPHENOXY)BENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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3,5-BIS(4-NITROPHENOXY)BENZOIC ACID Suppliers

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173550-33-9, 3,5-BIS(4-NITROPHENOXY)BENZOIC ACIDRelated Search:

1-METHOXY-3-(4-NITROPHENOXY) BENZENE 3-Phenoxybenzoic acid 3,5-BIS(4-NITROPHENOXY)BENZOIC ACID 3,5-BIS(4-AMINOPHENOXY)BENZOIC ACID 1,3-DIPHENOXYBENZENE 4-(3-METHOXYPHENOXY)ANILINE 1,3-Bis(4-aMinophenoxy)benzene AKOS BC-0783

3,5-BIS(4-NITROPHENOXY)BENZOIC ACID

3,5-BIS(4-NITROPHENOXY)BENZOIC ACID 98+%

3,5-Bis(4-nitrophenoxy)benzoic Acid &gt

NSC 400980

NSC400980

NSC-400980

Benzoic acid, 3,5-bis(4-nitrophenoxy)-

173550-33-9

C19H12N2O8

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