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Pseudocoptisine chloride

Product Name
Pseudocoptisine chloride
CAS No.
30044-78-1
Chemical Name
Pseudocoptisine chloride
Synonyms
Isocoptisine chloride;Pseudocoptisine chloride;Isocoptisine,anti-amnestic,Pseudocoptisine chloride,cytokines,anti-inflammatory,Pseudocoptisine,pro-inflammatory,RAW 264.7,Cholinesterase (ChE),inhibit,Inhibitor
CBNumber
CB93340603
Molecular Formula
C19H14ClNO4
Formula Weight
355.77
MOL File
30044-78-1.mol
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Pseudocoptisine chloride Property

storage temp. 
Store at -20°C
form 
Solid
color 
Yellow to brown
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0158969
Product name
Pseudocoptisinechloride
Purity
99.17%
Packaging
5mg
Price
$300
Updated
2021/12/16
ChemScene
Product number
CS-0158969
Product name
Pseudocoptisinechloride
Purity
99.17%
Packaging
10mg
Price
$480
Updated
2021/12/16
ChemScene
Product number
CS-0158969
Product name
Pseudocoptisinechloride
Purity
99.17%
Packaging
25mg
Price
$950
Updated
2021/12/16
ChemScene
Product number
CS-0158969
Product name
Pseudocoptisinechloride
Purity
99.17%
Packaging
50mg
Price
$1450
Updated
2021/12/16
ChemScene
Product number
CS-0158969
Product name
Pseudocoptisinechloride
Purity
99.17%
Packaging
100mg
Price
$2250
Updated
2021/12/16
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Pseudocoptisine chloride Chemical Properties,Usage,Production

Biological Activity

Pseudocoptisine (Isocoptisine) chloride is a quaternary alkaloid with benzylisoquinoline skeleton, was isolated from Corydalis Tuber. Pseudocoptisine chloride inhibits acetylcholinesterase (AChE) activity with an IC50 of 12.8 μM. Anti-inflammatory and anti-amnestic effects.

in vitro

Pseudocoptisine (0, 60, 90 μM; 1 hour) dose-dependently inhibited LPS-induced NO production in RAW264.7 cells.
Pseudocoptisine (30-90 μM; 1 hour; RAW264.7 cells) significantly reduces the LPS-induced TNF-α and IL-6 production and their mRNA expressions.
Pseudocoptisine acetate reduces levels of the pro-inflammatory mediators, such as, iNOS, COX-2, TNF-alpha, and IL-6 through the inhibition of NF-kappaB activation via the suppression of ERK and p38 phosphorylation in RAW 264.7 cells.

in vivo

The anti-amnesic activities of Pseudocoptisine in mice on the learning and memory impairments induced by scopolamine (1.0 mg/kg, ip) are examined. Pseudocoptisine (2.0 mg/kg, po) significantly reverses cognitive impairments in mice by passive avoidance test.

Pseudocoptisine chloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Pseudocoptisine chloride Suppliers

Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
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isunpharm@qq.com
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China
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4674
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Shijiazhuang Tancheng Biological Technology Co., Ltd
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0311-84309789 13833149888
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020-31155029 18902330969
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Hubei Wande Chemical Co., Ltd
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Tianmen Hengchang Chemical Co., Ltd
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TargetMol Chemicals Inc.
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Shanghai Yifei Biotechnology Co. , Ltd.
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Nanjing Shizhou Biology Technology Co.,Ltd
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RD International Technology Co., Limited
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market@ubiochem.com
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Cato Research Chemicals Inc.
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TLC Pharmaceutical Standards Ltd.
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Guangzhou CATO Research Chemicals Inc.
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Nantong HI-FUTURE Biology Co., Ltd.
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sales@chemhifuture.com
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3135
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Proteintech China
Tel
--
Fax
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Proteintech-CN@ptglab.com
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30044-78-1, Pseudocoptisine chlorideRelated Search:


  • Pseudocoptisine chloride
  • Isocoptisine chloride
  • Isocoptisine,anti-amnestic,Pseudocoptisine chloride,cytokines,anti-inflammatory,Pseudocoptisine,pro-inflammatory,RAW 264.7,Cholinesterase (ChE),inhibit,Inhibitor
  • 30044-78-1