ChemicalBook > CAS DataBase List > 2-((E)-5-((Z)-3-methyl-4-phenylbut-3-enylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid

2-((E)-5-((Z)-3-methyl-4-phenylbut-3-enylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid

Product Name
2-((E)-5-((Z)-3-methyl-4-phenylbut-3-enylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid
CAS No.
682775-70-8
Chemical Name
2-((E)-5-((Z)-3-methyl-4-phenylbut-3-enylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid
Synonyms
Epalrestat Methyl Ester;Naphthoic Acid Impurity 24;CGICFPQGDMJAMH-YGOOLXEZSA-N;Epalrestat (Z,Z)-Isomer Methyl Ester;2-((E)-5-((Z)-3-methyl-4-phenylbut-3-enylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid;3-Thiazolidineacetic acid, 5-(2-methyl-3-phenyl-2-propen-1-ylidene)-4-oxo-2-thioxo-, methyl ester
CBNumber
CB93353531
Molecular Formula
C16H15NO3S2
Formula Weight
333.43
MOL File
682775-70-8.mol
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2-((E)-5-((Z)-3-methyl-4-phenylbut-3-enylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid Property

Boiling point:
472.1±55.0 °C(Predicted)
Density 
1.34±0.1 g/cm3(Predicted)
solubility 
DMSO (Slightly), Ethyl Acetate (Slightly)
form 
Solid
pka
-3.51±0.20(Predicted)
color 
Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
E565310
Product name
(Z,Z)-EpalrestatMethylEster
Packaging
1mg
Price
$130
Updated
2021/12/16
TRC
Product number
E565310
Product name
(Z,Z)-EpalrestatMethylEster
Packaging
25mg
Price
$1465
Updated
2021/12/16
TRC
Product number
E565305
Product name
(E,Z)-EpalrestatMethylEster
Packaging
100mg
Price
$2605
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0004788
Product name
2-((Z)-5-((Z)-2-METHYL-3-PHENYLALLYLIDENE)-4-OXO-2-THIOXOTHIAZOLIDIN-3-YL)ACETIC METHYL ESTER
Purity
95.00%
Packaging
5MG
Price
$450.31
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
MTB0002487
Product name
(E,Z)-5-(2-METHYL-3-PHENYL-2-PROPEN-1-YLIDENE)-4-OXO-2-THIOXO-3-THIAZOLIDINEACETIC ACID METHYL ESTER
Purity
95.00%
Packaging
5MG
Price
$451.21
Updated
2021/12/16
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2-((E)-5-((Z)-3-methyl-4-phenylbut-3-enylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid Chemical Properties,Usage,Production

Uses

(Z,Z)-Epalrestat Methyl Ester is a stereoisomer of Epalrestat (E565300), an aldose reductase inhibitor. Used in the treatment of diabetic neuropathy.

2-((E)-5-((Z)-3-methyl-4-phenylbut-3-enylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-((E)-5-((Z)-3-methyl-4-phenylbut-3-enylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid Suppliers

China 18 India 1 Global 19

682775-70-8, 2-((E)-5-((Z)-3-methyl-4-phenylbut-3-enylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acidRelated Search:

3-Thiazolidineacetic acid, 5-[(2E)-2-methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-, (5E)- (Z,Z)-5-(2-Methyl-3-phenyl-propenylidene)-4-oxo-2-thioxo-3-thiazolidineacetic Acid 3-Thiazolidineaceticacid, 4-oxo-2-thioxo-, ethyl ester (2,4-DIOXO-1,3-THIAZOLIDIN-3-YL)ACETIC ACID (Z)-2-methyl-3-phenylacrylaldehyde Epalrestat 2-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]acetic acid (Z)-2-(5-benzylidene-4-oxo-2-thioxothiazolidin-3-yl)acetic acid 4-oxo-5-[(2E)-3-phenyl-2-propen-1-ylidene]-2-thioxo-, (5Z)- 3-Thiazolidineacetic acid, 4-oxo-2-thioxo-, methyl ester 3-Thiazolidineacetic acid, 5-[(2Z)-2-methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-, (5E)- Epalrestat Impurity 4

  • 2-((E)-5-((Z)-3-methyl-4-phenylbut-3-enylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid
  • CGICFPQGDMJAMH-YGOOLXEZSA-N
  • 3-Thiazolidineacetic acid, 5-(2-methyl-3-phenyl-2-propen-1-ylidene)-4-oxo-2-thioxo-, methyl ester
  • Epalrestat Methyl Ester
  • Epalrestat (Z,Z)-Isomer Methyl Ester
  • Naphthoic Acid Impurity 24
  • 682775-70-8