LYN-1604

Product Name: LYN-1604
CAS No.: 2088939-99-3
Chemical Name: LYN-1604
Synonyms: CS-2635;CS-2610;LYN-1604;LYN-1604 Hcl;LYN-1604 2HCl;LYN1604;LYN 1604;LYN-1604;LYN 1604;LYN1604;1-(4-(2-(2,4-Dichlorophenyl)-2-(naphthalen-2-ylmethoxy)ethyl)piperazin-1-yl)-2-(diisobutylamino)ethanone , LYN-1604;Ethanone, 2-[bis(2-methylpropyl)amino]-1-[4-[2-(2,4-dichlorophenyl)-2-(2-naphthalenylmethoxy)ethyl]-1-piperazinyl]-
CBNumber: CB93353955
Molecular Formula: C33H43Cl2N3O2
Formula Weight: 584.62
MOL File: 2088939-99-3.mol

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LYN-1604 Property

Boiling point:: 670.9±55.0 °C(Predicted)
Density: 1.168±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
form: A crystalline solid
pka: 8.03±0.50(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 24007
Product name: LYN-1604
Purity: ≥98%
Packaging: 1mg
Price: $81
Updated: 2024/03/01

Cayman Chemical

Product number: 24007
Product name: LYN-1604
Purity: ≥98%
Packaging: 5mg
Price: $317
Updated: 2024/03/01

Cayman Chemical

Product number: 24007
Product name: LYN-1604
Purity: ≥98%
Packaging: 10mg
Price: $593
Updated: 2024/03/01

AK Scientific

Product number: 2413EL
Product name: CID131801113
Packaging: 1mg
Price: $187
Updated: 2021/12/16

CSNpharm

Product number: CSN21387
Product name: LYN-1604
Packaging: 10mg
Price: $237
Updated: 2021/12/16

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LYN-1604 Chemical Properties,Usage,Production

Description

LYN-1604 is an activator of unc-51-like kinase 1 (ULK1; EC₅₀ = 18.94 nM). It increases Beclin 1, LC3-II, and total LC3 protein levels and reduces levels of p62 in human MDA-MB-231 triple-negative breast cancer (TNBC) cells in a concentration-dependent manner, indicating an increase in autophagy. It also increases the cleavage of the pro-apoptotic protein caspase-3. LYN-1604 decreases the viability of MDA-MB-231 cells in vitro (IC₅₀ = 1.66 μM), an effect that can be reversed by the autophagy inhibitor 3-methyladenine (3-MA; ). LYN-1604 (25, 50, and 100 mg/kg) reduces tumor growth in an MDA-MB-231 mouse xenograft model.

LYN-1604 Preparation Products And Raw materials

Raw materials

Preparation Products

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LYN-1604 Suppliers

China 46 United States 6 Global 52

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4575
Advantage: 55

Shanghaizehan biopharma technology co., Ltd.

Tel: 021-61350663 13052117465
Fax: 021-61350662
Email: sales@zehanbiopharma.com
Country: China
ProdList: 1004
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Shanghai Rechem science Co., Ltd.

Tel: 21-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2986
Advantage: 58

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 7295
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 29785
Advantage: 68

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

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View Lastest Price from LYN-1604 manufacturers

Career Henan Chemica Co

Product: LYN-1604 2088939-99-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: MIn98%HPLC/LC
Supply Ability: 100KGS
Release date: 2020-10-29

2088939-99-3, LYN-1604Related Search:

LYN-1604

LYN-1604 Hcl

CS-2610

CS-2635

LYN-1604;LYN 1604;LYN1604

LYN1604;LYN 1604

Ethanone, 2-[bis(2-methylpropyl)amino]-1-[4-[2-(2,4-dichlorophenyl)-2-(2-naphthalenylmethoxy)ethyl]-1-piperazinyl]-

LYN-1604 2HCl

1-(4-(2-(2,4-Dichlorophenyl)-2-(naphthalen-2-ylmethoxy)ethyl)piperazin-1-yl)-2-(diisobutylamino)ethanone , LYN-1604

2088939-99-3

C33H43Cl2N3O2