LM22B-10
- Product Name
- LM22B-10
- CAS No.
- 342777-54-2
- Chemical Name
- LM22B-10
- Synonyms
- LM22B-10;2,2',2',2'''-[[(4-Chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakisethanol;Ethanol, 2,2',2'',2'''-[[(4-chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakis-;2,2',2'',2'''-((((4-Chlorophenyl)methylene)bis(4,1-phenylene))bis(azanetriyl))tetrakis(ethan-1-ol);2-[[4-[[4-[BIS-(2-HYDROXYETHYL)-AMINO]-PHENYL]-(4-CHLORO-PHENYL)-METHYL]-PHENYL]-(2-HYDROXY-ETHYL)-AMINO]-ETHANOL;inhibit,Trk Receptor,Akt,LM-22B-10,LM22B-10,LM22B 10,Tropomyosin related kinase receptor,ERK,PKB,Inhibitor,Protein kinase B,Extracellular signal regulated kinases
- CBNumber
- CB93356163
- Molecular Formula
- C27H33ClN2O4
- Formula Weight
- 485.01
- MOL File
- 342777-54-2.mol
LM22B-10 Property
- Boiling point:
- 718.9±60.0 °C(Predicted)
- Density
- 1.287±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
- form
- A crystalline solid
- pka
- 14.00±0.10(Predicted)
- color
- Light green to green
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SML2461
- Product name
- LM22B-10
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $102
- Updated
- 2024/03/01
- Product number
- SML2461
- Product name
- LM22B-10
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $411
- Updated
- 2024/03/01
- Product number
- 29037
- Product name
- LM22B-10
- Packaging
- 5mg
- Price
- $93
- Updated
- 2024/03/01
- Product number
- 29037
- Product name
- LM22B-10
- Packaging
- 25mg
- Price
- $365
- Updated
- 2024/03/01
- Product number
- 29037
- Product name
- LM22B-10
- Packaging
- 10mg
- Price
- $166
- Updated
- 2024/03/01
LM22B-10 Chemical Properties,Usage,Production
Uses
LM22B-10 is a TrkB and TrkC agonist. Exhibits neurotrophic activity (EC50 = 200-300 nM), improves survival and increases neurite outgrowth in hippocampal cells in vitro. Exhibits no significant activity in a screen of 57 other receptors and transporters. Inhibits binding of BDNF and neurotrophin-3 to TrkB and TrkC, respectively. Active in vivo and brain penetrant.
storage
Store at -20°C
LM22B-10 Preparation Products And Raw materials
Raw materials
Preparation Products
LM22B-10 Suppliers
- Tel
- --
- Fax
- --
- customerservice@tocris.co.uk
- Country
- United Kingdom
- ProdList
- 5726
- Advantage
- 77